JP2019523653A5 - - Google Patents
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- JP2019523653A5 JP2019523653A5 JP2019514173A JP2019514173A JP2019523653A5 JP 2019523653 A5 JP2019523653 A5 JP 2019523653A5 JP 2019514173 A JP2019514173 A JP 2019514173A JP 2019514173 A JP2019514173 A JP 2019514173A JP 2019523653 A5 JP2019523653 A5 JP 2019523653A5
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- Prior art keywords
- seq
- antibody
- heavy chain
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2016/083653 | 2016-05-27 | ||
| PCT/CN2016/083653 WO2017201731A1 (en) | 2016-05-27 | 2016-05-27 | Antibodies, composition and kits comprising same, and methods of use thereof |
| PCT/CN2017/086280 WO2017202387A1 (en) | 2016-05-27 | 2017-05-27 | Antibodies, composition and kits comprising same, and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523653A JP2019523653A (ja) | 2019-08-29 |
| JP2019523653A5 true JP2019523653A5 (https=) | 2020-07-09 |
| JP7210026B2 JP7210026B2 (ja) | 2023-01-23 |
Family
ID=60410923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514173A Active JP7210026B2 (ja) | 2016-05-27 | 2017-05-27 | 抗体、抗体を含む組成物およびキット、ならびにそれらの使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11192946B2 (https=) |
| EP (1) | EP3464346A4 (https=) |
| JP (1) | JP7210026B2 (https=) |
| KR (1) | KR102540512B1 (https=) |
| CN (1) | CN109563155B (https=) |
| AU (1) | AU2017269526B2 (https=) |
| CA (1) | CA3025217A1 (https=) |
| WO (2) | WO2017201731A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017201731A1 (en) | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
| RU2020121415A (ru) * | 2017-11-30 | 2021-12-30 | Био-Тера Солюшнз, Лтд. | Жидкий препарат гуманизированного антитела для лечения заболеваний, опосредованных ил-6 |
| CN119662544A (zh) | 2018-03-14 | 2025-03-21 | 湖南思为康医药有限公司 | 用于降低毒性的免疫细胞修饰以及其在过继细胞疗法中的用途 |
| WO2019241216A1 (en) * | 2018-06-14 | 2019-12-19 | Bioatla, Llc | Multi-specific antibody constructs |
| CN113677356A (zh) * | 2019-01-07 | 2021-11-19 | 湖南思为康医药有限公司 | 用于降低毒性的共表达嵌合抗原受体和il-6拮抗剂的修饰免疫细胞及其在过继细胞疗法中的用途 |
| CN113710229B (zh) | 2019-02-25 | 2026-01-06 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| CN113316587B (zh) * | 2019-05-20 | 2024-03-26 | 南通壹宸生物医药科技有限公司 | 一种双特异性分子及其制备与用途 |
| WO2021164107A1 (zh) * | 2020-02-19 | 2021-08-26 | 中国科学技术大学 | Il-6受体抗体的新用途 |
| CN116261448A (zh) * | 2020-08-19 | 2023-06-13 | 百奥泰生物制药股份有限公司 | 用于治疗il-6相关疾病的包含高浓度人源化抗体的液体制剂 |
| CN118632873A (zh) * | 2022-11-07 | 2024-09-10 | 北京伟德杰生物科技有限公司 | 双特异性抗体及其应用 |
| CN118591566A (zh) * | 2022-11-07 | 2024-09-03 | 北京伟德杰生物科技有限公司 | 双功能融合蛋白及其应用 |
| CN120818056A (zh) * | 2024-04-15 | 2025-10-21 | 北京伟德杰生物科技有限公司 | 抗白介素6受体的抗体及其应用 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| WO1990006952A1 (fr) | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Facteur de stimulation de colonies de granulocytes modifies chimiquement |
| US5270202A (en) | 1989-11-03 | 1993-12-14 | Syamal Raychaudhuri | Anti-idiotypic antibodies to human melanoma-associated proteoglycan antigen |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| CU22615A1 (es) | 1994-06-30 | 2000-02-10 | Centro Inmunologia Molecular | Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos |
| US5795737A (en) | 1994-09-19 | 1998-08-18 | The General Hospital Corporation | High level expression of proteins |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| EP1490494A1 (en) | 2002-04-01 | 2004-12-29 | Walter Reed Army Institute of Research | Method of designing synthetic nucleic acid sequences for optimal protein expression in a host cell |
| WO2005090405A1 (ja) | 2004-03-24 | 2005-09-29 | Chugai Seiyaku Kabushiki Kaisha | インターロイキン－６受容体に対するヒト型化抗体のサブタイプ |
| CN104761637B (zh) | 2006-03-31 | 2021-10-15 | 中外制药株式会社 | 调控抗体血液动力学的方法 |
| JP5307708B2 (ja) | 2006-06-02 | 2013-10-02 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | ヒトｉｌ−６受容体に対する高親和性抗体 |
| WO2008000632A1 (en) | 2006-06-29 | 2008-01-03 | Dsm Ip Assets B.V. | A method for achieving improved polypeptide expression |
| ES2595638T3 (es) | 2007-09-26 | 2017-01-02 | Chugai Seiyaku Kabushiki Kaisha | Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR |
| MX2010003329A (es) * | 2007-09-26 | 2010-04-27 | Chugai Pharmaceutical Co Ltd | Anticuerpo anti-receptor de il-6. |
| TWI440469B (zh) * | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| MX342810B (es) * | 2011-03-03 | 2016-10-13 | Apexigen Inc | Anticuerpos del receptor anti-interleucina-6 (anti-il-6) y sus metodos de uso. |
| US9487590B2 (en) * | 2012-09-25 | 2016-11-08 | Cytomx Therapeutics, Inc. | Activatable antibodies that bind interleukin-6 receptor and methods of use thereof |
| WO2017201731A1 (en) | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
-
2016
- 2016-05-27 WO PCT/CN2016/083653 patent/WO2017201731A1/en not_active Ceased
-
2017
- 2017-05-27 KR KR1020187037865A patent/KR102540512B1/ko active Active
- 2017-05-27 JP JP2019514173A patent/JP7210026B2/ja active Active
- 2017-05-27 WO PCT/CN2017/086280 patent/WO2017202387A1/en not_active Ceased
- 2017-05-27 AU AU2017269526A patent/AU2017269526B2/en active Active
- 2017-05-27 CA CA3025217A patent/CA3025217A1/en active Pending
- 2017-05-27 EP EP17802233.1A patent/EP3464346A4/en active Pending
- 2017-05-27 CN CN201780046893.5A patent/CN109563155B/zh active Active
-
2018
- 2018-11-26 US US16/200,512 patent/US11192946B2/en active Active
-
2021
- 2021-11-04 US US17/519,069 patent/US12006362B2/en active Active
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