JP2023507118A5 - - Google Patents
Info
- Publication number
- JP2023507118A5 JP2023507118A5 JP2022536616A JP2022536616A JP2023507118A5 JP 2023507118 A5 JP2023507118 A5 JP 2023507118A5 JP 2022536616 A JP2022536616 A JP 2022536616A JP 2022536616 A JP2022536616 A JP 2022536616A JP 2023507118 A5 JP2023507118 A5 JP 2023507118A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- stem cells
- function
- loss
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962950063P | 2019-12-18 | 2019-12-18 | |
| US62/950,063 | 2019-12-18 | ||
| US202063025735P | 2020-05-15 | 2020-05-15 | |
| US63/025,735 | 2020-05-15 | ||
| US202063115592P | 2020-11-18 | 2020-11-18 | |
| US63/115,592 | 2020-11-18 | ||
| PCT/US2020/066256 WO2021127594A1 (en) | 2019-12-18 | 2020-12-18 | Engineered cells for therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023507118A JP2023507118A (ja) | 2023-02-21 |
| JP2023507118A5 true JP2023507118A5 (https=) | 2023-12-25 |
Family
ID=76478017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022536616A Pending JP2023507118A (ja) | 2019-12-18 | 2020-12-18 | 治療のための操作された細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230053028A1 (https=) |
| EP (1) | EP4076479A4 (https=) |
| JP (1) | JP2023507118A (https=) |
| KR (1) | KR20220119063A (https=) |
| CN (1) | CN114929250A (https=) |
| AU (1) | AU2020405203A1 (https=) |
| CA (1) | CA3164660A1 (https=) |
| IL (1) | IL293946A (https=) |
| WO (1) | WO2021127594A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120174005A (zh) | 2019-02-13 | 2025-06-20 | 比姆医疗股份有限公司 | 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞 |
| EP4034138A4 (en) | 2019-09-27 | 2024-07-31 | Beam Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS |
| CA3196831A1 (en) | 2020-09-25 | 2022-03-31 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| KR20230118887A (ko) | 2020-12-03 | 2023-08-14 | 센츄리 쎄라퓨틱스 인코포레이티드 | 유전자 조작 세포 및 이의 용도 |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| WO2023108107A2 (en) * | 2021-12-10 | 2023-06-15 | Beam Therapeutics Inc. | Modified immune cells and methods of using the same |
| CN117384853B (zh) * | 2022-07-11 | 2025-12-19 | 士泽生物医药（苏州）有限公司 | 一种表达pvr的通用型细胞及其制备方法 |
| AU2023356353A1 (en) * | 2022-10-05 | 2025-05-08 | Garuda Therapeutics, Inc. | Modified hematopoietic stem cells and progenies thereof |
| WO2025166325A1 (en) * | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025238593A1 (en) * | 2024-05-16 | 2025-11-20 | Fondazione Istituto Italiano Di Tecnologia | DESIGN OF SYNTHETIC miRNAS TO RESTORE THE CORRECT GENE DOSAGE OF GENES ASSOCIATED WITH T LYMPHOCYTE EXHAUSTION |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US20030073623A1 (en) * | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| US9233926B2 (en) * | 2008-09-17 | 2016-01-12 | Sanford-Burnham Medical Research Institute | Compounds for stem cell differentiation |
| EP3495497B1 (en) * | 2011-04-28 | 2021-03-24 | Life Technologies Corporation | Methods and compositions for multiplex pcr |
| KR20260004568A (ko) * | 2016-04-19 | 2026-01-08 | 더 브로드 인스티튜트, 인코퍼레이티드 | 신규한 crispr 효소 및 시스템 |
| AU2017347854B2 (en) * | 2016-10-27 | 2022-12-08 | Intima Bioscience, Inc. | Viral methods of T cell therapy |
| EP3612210A4 (en) * | 2017-04-19 | 2021-01-27 | Board Of Regents, The University Of Texas System | MANIPULATED ANTIGEN RECEPTORS EXPRESSING IMMUNE CELLS |
| BR112020006601A2 (pt) * | 2017-10-02 | 2020-12-08 | Genedit Inc. | Rna guia de cpf1 modificado |
| WO2019089884A2 (en) * | 2017-11-01 | 2019-05-09 | Editas Medicine, Inc. | Methods, compositions and components for crispr-cas9 editing of tgfbr2 in t cells for immunotherapy |
| KR102907245B1 (ko) * | 2018-03-14 | 2026-01-05 | 에디타스 메디신, 인코포레이티드 | 혈색소병증 치료를 위한 시스템 및 방법 |
| EP3790562A4 (en) * | 2018-05-11 | 2022-01-12 | The Regents of the University of California | MODIFICATION OF IMMUNE CELLS TO INCREASE ACTIVITY |
| MX2021006208A (es) * | 2018-11-28 | 2021-10-01 | Univ Texas | Edición por multiplexación del genoma de células inmunitarias para mejorar la funcionalidad y resistencia al entorno supresor. |
-
2020
- 2020-12-18 IL IL293946A patent/IL293946A/en unknown
- 2020-12-18 CN CN202080091509.5A patent/CN114929250A/zh active Pending
- 2020-12-18 AU AU2020405203A patent/AU2020405203A1/en active Pending
- 2020-12-18 JP JP2022536616A patent/JP2023507118A/ja active Pending
- 2020-12-18 CA CA3164660A patent/CA3164660A1/en active Pending
- 2020-12-18 WO PCT/US2020/066256 patent/WO2021127594A1/en not_active Ceased
- 2020-12-18 US US17/786,753 patent/US20230053028A1/en active Pending
- 2020-12-18 KR KR1020227023757A patent/KR20220119063A/ko active Pending
- 2020-12-18 EP EP20902223.5A patent/EP4076479A4/en active Pending
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