JP2023507118A - 治療のための操作された細胞 - Google Patents

治療のための操作された細胞 Download PDF

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JP2023507118A
JP2023507118A JP2022536616A JP2022536616A JP2023507118A JP 2023507118 A JP2023507118 A JP 2023507118A JP 2022536616 A JP2022536616 A JP 2022536616A JP 2022536616 A JP2022536616 A JP 2022536616A JP 2023507118 A JP2023507118 A JP 2023507118A
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cell
receptor
cells
rna
loss
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JP2023507118A5 (https=
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ジー グラント ウェルステッド
ジョン イル ムーン
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エディタス・メディシン、インコーポレイテッド
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JP2022536616A 2019-12-18 2020-12-18 治療のための操作された細胞 Pending JP2023507118A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962950063P 2019-12-18 2019-12-18
US62/950,063 2019-12-18
US202063025735P 2020-05-15 2020-05-15
US63/025,735 2020-05-15
US202063115592P 2020-11-18 2020-11-18
US63/115,592 2020-11-18
PCT/US2020/066256 WO2021127594A1 (en) 2019-12-18 2020-12-18 Engineered cells for therapy

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JP2023507118A true JP2023507118A (ja) 2023-02-21
JP2023507118A5 JP2023507118A5 (https=) 2023-12-25

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US (1) US20230053028A1 (https=)
EP (1) EP4076479A4 (https=)
JP (1) JP2023507118A (https=)
KR (1) KR20220119063A (https=)
CN (1) CN114929250A (https=)
AU (1) AU2020405203A1 (https=)
CA (1) CA3164660A1 (https=)
IL (1) IL293946A (https=)
WO (1) WO2021127594A1 (https=)

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CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
CA3196831A1 (en) 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
KR20230118887A (ko) 2020-12-03 2023-08-14 센츄리 쎄라퓨틱스 인코포레이티드 유전자 조작 세포 및 이의 용도
AR124414A1 (es) 2020-12-18 2023-03-22 Century Therapeutics Inc Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
WO2023108107A2 (en) * 2021-12-10 2023-06-15 Beam Therapeutics Inc. Modified immune cells and methods of using the same
CN117384853B (zh) * 2022-07-11 2025-12-19 士泽生物医药（苏州）有限公司 一种表达pvr的通用型细胞及其制备方法
AU2023356353A1 (en) * 2022-10-05 2025-05-08 Garuda Therapeutics, Inc. Modified hematopoietic stem cells and progenies thereof
WO2025166325A1 (en) * 2024-02-02 2025-08-07 Editas Medicine, Inc. MODIFIED GUIDE RNAs
WO2025238593A1 (en) * 2024-05-16 2025-11-20 Fondazione Istituto Italiano Di Tecnologia DESIGN OF SYNTHETIC miRNAS TO RESTORE THE CORRECT GENE DOSAGE OF GENES ASSOCIATED WITH T LYMPHOCYTE EXHAUSTION

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IL293946A (en) 2022-08-01
EP4076479A1 (en) 2022-10-26
CA3164660A1 (en) 2021-06-24
WO2021127594A1 (en) 2021-06-24
EP4076479A4 (en) 2024-05-22
AU2020405203A1 (en) 2022-07-14
US20230053028A1 (en) 2023-02-16
KR20220119063A (ko) 2022-08-26

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