JP2023502780A - 腫瘍浸潤リンパ球の活性化及び増殖方法 - Google Patents
腫瘍浸潤リンパ球の活性化及び増殖方法 Download PDFInfo
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025133444A JP2025159098A (ja) | 2019-11-25 | 2025-08-08 | 腫瘍浸潤リンパ球の活性化及び増殖方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962940035P | 2019-11-25 | 2019-11-25 | |
| US62/940,035 | 2019-11-25 | ||
| US202063081539P | 2020-09-22 | 2020-09-22 | |
| US63/081,539 | 2020-09-22 | ||
| PCT/US2020/062094 WO2021108455A1 (en) | 2019-11-25 | 2020-11-24 | Methods for activation and expansion of tumor infiltrating lymphocytes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025133444A Division JP2025159098A (ja) | 2019-11-25 | 2025-08-08 | 腫瘍浸潤リンパ球の活性化及び増殖方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023502780A true JP2023502780A (ja) | 2023-01-25 |
| JPWO2021108455A5 JPWO2021108455A5 (https=) | 2023-12-01 |
| JP2023502780A5 JP2023502780A5 (https=) | 2023-12-01 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022530237A Withdrawn JP2023502780A (ja) | 2019-11-25 | 2020-11-24 | 腫瘍浸潤リンパ球の活性化及び増殖方法 |
| JP2025133444A Pending JP2025159098A (ja) | 2019-11-25 | 2025-08-08 | 腫瘍浸潤リンパ球の活性化及び増殖方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025133444A Pending JP2025159098A (ja) | 2019-11-25 | 2025-08-08 | 腫瘍浸潤リンパ球の活性化及び増殖方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240376428A1 (https=) |
| EP (1) | EP4065233A4 (https=) |
| JP (2) | JP2023502780A (https=) |
| KR (1) | KR20220119038A (https=) |
| CN (1) | CN115003387A (https=) |
| AU (1) | AU2020392094A1 (https=) |
| CA (1) | CA3162272A1 (https=) |
| WO (1) | WO2021108455A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020232691B2 (en) | 2019-03-05 | 2023-06-29 | Nkarta, Inc. | CD19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| US12365871B2 (en) | 2020-04-28 | 2025-07-22 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| WO2021252804A1 (en) | 2020-06-12 | 2021-12-16 | Nkarta, Inc. | Genetically modified natural killer cells for cd70-directed cancer immunotherapy |
| CN114901805B (zh) | 2020-11-19 | 2023-07-25 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的培养方法及其用途 |
| CN117616115A (zh) * | 2021-08-03 | 2024-02-27 | 苏州沙砾生物科技有限公司 | 一种修饰的肿瘤浸润淋巴细胞及其用途 |
| WO2023039410A1 (en) * | 2021-09-08 | 2023-03-16 | KSQ Therapeutics, Inc. | Lymphocyte potency assay |
| CN118414422A (zh) * | 2021-12-30 | 2024-07-30 | 苏州沙砾生物科技有限公司 | 一种修饰的肿瘤浸润淋巴细胞及其用途 |
| WO2023138598A1 (zh) * | 2022-01-19 | 2023-07-27 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞在疾病治疗中的用途 |
| EP4471128A4 (en) * | 2022-01-29 | 2026-03-04 | Suzhou Grit Biotechnology Co Ltd | Modified tumor infiltrating lymphocyte and use thereof |
| CA3254363A1 (en) * | 2022-03-07 | 2023-09-14 | Nkarta, Inc. | Multiplex gene-edited cells for CD70-led cancer immunotherapy |
| CN117417894A (zh) * | 2023-09-15 | 2024-01-19 | 毕诺济(上海)生物技术有限公司 | 敲除Roquin-1和/或Regnase-1基因的肿瘤浸润淋巴细胞及其应用 |
| WO2025092690A1 (zh) * | 2023-10-30 | 2025-05-08 | 苏州沙砾生物科技有限公司 | 一种修饰的细胞及其用途 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008522951A (ja) * | 2004-07-19 | 2008-07-03 | ベイラー・カレツジ・オブ・メデイシン | サイトカインシグナル伝達調節物質の調節および免疫療法のための応用 |
| WO2010098429A1 (ja) * | 2009-02-27 | 2010-09-02 | 国立大学法人大阪大学 | 免疫アジュバント組成物、及びその利用 |
| JP2015533493A (ja) * | 2012-09-25 | 2015-11-26 | ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 可動性ナノマトリックスによるt細胞のポリクローナル刺激方法 |
| JP2017524348A (ja) * | 2014-06-10 | 2017-08-31 | モナッシュ ユニバーシティ | 養子細胞移入のためのptpn2阻害を用いた白血球の産生方法 |
| JP2017528133A (ja) * | 2014-09-04 | 2017-09-28 | ステムセル テクノロジーズ インコーポレーティッド | T細胞またはnk細胞を活性化および増加させるための、可溶性抗体複合体 |
| CN108753718A (zh) * | 2018-06-20 | 2018-11-06 | 淮安诺康生物科技有限公司 | 肿瘤浸润淋巴细胞til的体外扩增方法 |
| WO2018209115A1 (en) * | 2017-05-10 | 2018-11-15 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof |
| WO2019178421A1 (en) * | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| WO2019178420A1 (en) * | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| JP2019531744A (ja) * | 2016-10-31 | 2019-11-07 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球拡大培養用の改変人工抗原提示細胞 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3197849A1 (en) * | 2014-12-29 | 2016-07-07 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| SG11201708516YA (en) * | 2015-04-17 | 2017-11-29 | David Maxwell Barrett | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
| WO2017087784A1 (en) * | 2015-11-18 | 2017-05-26 | Duke University | Tumor infiltrating lymphocytes for treatment of cancer |
-
2020
- 2020-11-24 KR KR1020227021333A patent/KR20220119038A/ko active Pending
- 2020-11-24 US US17/779,458 patent/US20240376428A1/en active Pending
- 2020-11-24 EP EP20892396.1A patent/EP4065233A4/en active Pending
- 2020-11-24 JP JP2022530237A patent/JP2023502780A/ja not_active Withdrawn
- 2020-11-24 WO PCT/US2020/062094 patent/WO2021108455A1/en not_active Ceased
- 2020-11-24 CN CN202080093941.8A patent/CN115003387A/zh active Pending
- 2020-11-24 AU AU2020392094A patent/AU2020392094A1/en active Pending
- 2020-11-24 CA CA3162272A patent/CA3162272A1/en active Pending
-
2025
- 2025-08-08 JP JP2025133444A patent/JP2025159098A/ja active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008522951A (ja) * | 2004-07-19 | 2008-07-03 | ベイラー・カレツジ・オブ・メデイシン | サイトカインシグナル伝達調節物質の調節および免疫療法のための応用 |
| WO2010098429A1 (ja) * | 2009-02-27 | 2010-09-02 | 国立大学法人大阪大学 | 免疫アジュバント組成物、及びその利用 |
| JP2015533493A (ja) * | 2012-09-25 | 2015-11-26 | ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 可動性ナノマトリックスによるt細胞のポリクローナル刺激方法 |
| JP2017524348A (ja) * | 2014-06-10 | 2017-08-31 | モナッシュ ユニバーシティ | 養子細胞移入のためのptpn2阻害を用いた白血球の産生方法 |
| JP2017528133A (ja) * | 2014-09-04 | 2017-09-28 | ステムセル テクノロジーズ インコーポレーティッド | T細胞またはnk細胞を活性化および増加させるための、可溶性抗体複合体 |
| JP2019531744A (ja) * | 2016-10-31 | 2019-11-07 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球拡大培養用の改変人工抗原提示細胞 |
| WO2018209115A1 (en) * | 2017-05-10 | 2018-11-15 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof |
| WO2019178421A1 (en) * | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| WO2019178420A1 (en) * | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| CN108753718A (zh) * | 2018-06-20 | 2018-11-06 | 淮安诺康生物科技有限公司 | 肿瘤浸润淋巴细胞til的体外扩增方法 |
Non-Patent Citations (4)
| Title |
|---|
| BIANCA HEEMSKERK ET AL., CANCER IMMUNOLOGY RESEARCH, vol. 7 (2_Supplement): B016, JPN6024044020, 1 February 2019 (2019-02-01), ISSN: 0005569907 * |
| MARCEL J. FLENS ET AL., CANCER IMMUNOLOGY IMMUNOTHERAPY, vol. 37, JPN6024044019, 1993, pages 323 - 328, ISSN: 0005569906 * |
| MARIE-ANDREE FORGET ET AL., FRONTIERS IN IMMUNOLOGY, vol. Vol. 8, Article 908, JPN6024044017, 2017, pages 1 - 8, ISSN: 0005569905 * |
| QUNRUI YE ET AL., JOURNAL OF TRANSLATIONAL MEDICINE, vol. 9:131, JPN6024044015, 2011, pages 1 - 13, ISSN: 0005569904 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA3162272A1 (en) | 2021-06-03 |
| AU2020392094A1 (en) | 2022-06-23 |
| WO2021108455A1 (en) | 2021-06-03 |
| US20240376428A1 (en) | 2024-11-14 |
| EP4065233A1 (en) | 2022-10-05 |
| EP4065233A4 (en) | 2024-07-10 |
| JP2025159098A (ja) | 2025-10-17 |
| KR20220119038A (ko) | 2022-08-26 |
| CN115003387A (zh) | 2022-09-02 |
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