AU2020392094A1 - Methods for activation and expansion of tumor infiltrating lymphocytes - Google Patents
Methods for activation and expansion of tumor infiltrating lymphocytes Download PDFInfo
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| US12365871B2 (en) | 2020-04-28 | 2025-07-22 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| WO2021252804A1 (en) | 2020-06-12 | 2021-12-16 | Nkarta, Inc. | Genetically modified natural killer cells for cd70-directed cancer immunotherapy |
| CN114901805B (zh) | 2020-11-19 | 2023-07-25 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞的培养方法及其用途 |
| CN117616115A (zh) * | 2021-08-03 | 2024-02-27 | 苏州沙砾生物科技有限公司 | 一种修饰的肿瘤浸润淋巴细胞及其用途 |
| WO2023039410A1 (en) * | 2021-09-08 | 2023-03-16 | KSQ Therapeutics, Inc. | Lymphocyte potency assay |
| CN118414422A (zh) * | 2021-12-30 | 2024-07-30 | 苏州沙砾生物科技有限公司 | 一种修饰的肿瘤浸润淋巴细胞及其用途 |
| WO2023138598A1 (zh) * | 2022-01-19 | 2023-07-27 | 苏州沙砾生物科技有限公司 | 肿瘤浸润淋巴细胞在疾病治疗中的用途 |
| EP4471128A4 (en) * | 2022-01-29 | 2026-03-04 | Suzhou Grit Biotechnology Co Ltd | Modified tumor infiltrating lymphocyte and use thereof |
| CA3254363A1 (en) * | 2022-03-07 | 2023-09-14 | Nkarta, Inc. | Multiplex gene-edited cells for CD70-led cancer immunotherapy |
| CN117417894A (zh) * | 2023-09-15 | 2024-01-19 | 毕诺济(上海)生物技术有限公司 | 敲除Roquin-1和/或Regnase-1基因的肿瘤浸润淋巴细胞及其应用 |
| WO2025092690A1 (zh) * | 2023-10-30 | 2025-05-08 | 苏州沙砾生物科技有限公司 | 一种修饰的细胞及其用途 |
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| EP2711418B1 (en) * | 2012-09-25 | 2017-08-23 | Miltenyi Biotec GmbH | Method for polyclonal stimulation of T cells by flexible nanomatrices |
| WO2015188228A1 (en) * | 2014-06-10 | 2015-12-17 | Monash University | Method of producing leukocytes using ptpn2 inhibition for adoptive cell transfer |
| BR112017004270B1 (pt) * | 2014-09-04 | 2023-03-07 | Stemcell Technologies Inc | Método de ativação de células t ou células nk |
| CA3197849A1 (en) * | 2014-12-29 | 2016-07-07 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| SG11201708516YA (en) * | 2015-04-17 | 2017-11-29 | David Maxwell Barrett | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
| WO2017087784A1 (en) * | 2015-11-18 | 2017-05-26 | Duke University | Tumor infiltrating lymphocytes for treatment of cancer |
| TWI788307B (zh) * | 2016-10-31 | 2023-01-01 | 美商艾歐凡斯生物治療公司 | 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞 |
| US11261428B2 (en) * | 2018-03-15 | 2022-03-01 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
| US20200224161A1 (en) * | 2017-05-10 | 2020-07-16 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof |
| KR20200130826A (ko) * | 2018-03-15 | 2020-11-20 | 케이에스큐 세러퓨틱스 인코포레이티드 | 개선된 면역요법을 위한 유전자-조절 조성물 및 방법 |
| CN108753718A (zh) * | 2018-06-20 | 2018-11-06 | 淮安诺康生物科技有限公司 | 肿瘤浸润淋巴细胞til的体外扩增方法 |
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