JP2023501956A5 - - Google Patents
Info
- Publication number
- JP2023501956A5 JP2023501956A5 JP2022525376A JP2022525376A JP2023501956A5 JP 2023501956 A5 JP2023501956 A5 JP 2023501956A5 JP 2022525376 A JP2022525376 A JP 2022525376A JP 2022525376 A JP2022525376 A JP 2022525376A JP 2023501956 A5 JP2023501956 A5 JP 2023501956A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridine
- pyrazole
- triazolo
- isopropyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962929299P | 2019-11-01 | 2019-11-01 | |
| US62/929,299 | 2019-11-01 | ||
| PCT/US2020/058081 WO2021087181A1 (en) | 2019-11-01 | 2020-10-30 | Substituted pyrazole compounds as toll receptor inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023501956A JP2023501956A (ja) | 2023-01-20 |
| JP2023501956A5 true JP2023501956A5 (enExample) | 2023-11-07 |
| JP7652772B2 JP7652772B2 (ja) | 2025-03-27 |
Family
ID=73544353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022525376A Active JP7652772B2 (ja) | 2019-11-01 | 2020-10-30 | 置換ピラゾール化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230117470A1 (enExample) |
| EP (1) | EP4051388A1 (enExample) |
| JP (1) | JP7652772B2 (enExample) |
| KR (1) | KR20220097434A (enExample) |
| CN (1) | CN114929345B (enExample) |
| WO (1) | WO2021087181A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230171469A (ko) | 2021-04-16 | 2023-12-20 | 길리애드 사이언시즈, 인코포레이티드 | 티에노피롤 화합물 |
| EP4398989A1 (en) | 2021-09-10 | 2024-07-17 | Gilead Sciences, Inc. | Thienopyrrole compounds |
| EP4436975A1 (en) * | 2021-11-23 | 2024-10-02 | Genentech, Inc. | Spirocyclic cyclic modulators of cholesterol biosynthesis and their use for promoting remyelination |
| WO2025261449A1 (zh) * | 2024-06-19 | 2025-12-26 | 浙江扬厉医药技术有限公司 | 一种parp1抑制剂吡啶酰胺类化合物、中间体及其制备方法 |
| WO2026002036A1 (zh) * | 2024-06-26 | 2026-01-02 | 北京双鹤润创科技有限公司 | 一种化合物及其用途 |
| CN119684287A (zh) * | 2024-12-18 | 2025-03-25 | 烟台新药创制山东省实验室 | 4-(3-(哌啶-4-基)-1H-吡唑-5-基)-1H-吡咯[2,3-b]吡啶衍生物及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1971594A2 (en) * | 2005-11-21 | 2008-09-24 | Biogen Idec MA Inc. | Substituted pyrazalones |
| EP2304366A2 (en) * | 2008-05-30 | 2011-04-06 | Foster Wheeler Energia Oy | Method of and system for generating power by oxyfuel combustion |
| CA2738929A1 (en) * | 2008-10-17 | 2010-04-22 | Boehringer Ingelheim International Gmbh | Heteroaryl substituted indole compounds useful as mmp-13 inhibitors |
| MX2011005221A (es) * | 2008-11-21 | 2011-08-03 | Raqualia Pharma Inc | Nuevo derivado de la pirazol-3-carboxamida que tiene actividad de antagonista del receptor de 5-ht2b. |
| JP2012102018A (ja) * | 2009-03-03 | 2012-05-31 | Astellas Pharma Inc | アミド化合物 |
| CA2878792A1 (en) * | 2012-07-12 | 2014-01-16 | Chiesi Farmaceutici S.P.A. | Inhibition of enzymes |
| US9550778B2 (en) * | 2014-10-03 | 2017-01-24 | Vanderbilt University | Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5 |
| KR102434226B1 (ko) * | 2016-06-30 | 2022-08-19 | 한미약품 주식회사 | Alk5 억제제로서의 신규 피라졸 유도체 및 이의 용도 |
| CN110869360B (zh) * | 2017-07-12 | 2023-12-15 | 百时美施贵宝公司 | 作为rock抑制剂的苯乙酰胺类 |
| FI3728252T3 (fi) * | 2017-12-18 | 2023-10-18 | Bristol Myers Squibb Co | 4-atsaindoliyhdisteitä |
| JP7313354B2 (ja) * | 2017-12-19 | 2023-07-24 | ブリストル－マイヤーズ スクイブ カンパニー | Ｔｌｒ阻害剤として有用なアミド置換されたインドール化合物 |
| WO2019136147A1 (en) * | 2018-01-03 | 2019-07-11 | The Board Of Trustees Of The University Of Illinois | Toll-like receptor signaling inhibitors |
-
2020
- 2020-10-30 JP JP2022525376A patent/JP7652772B2/ja active Active
- 2020-10-30 KR KR1020227018003A patent/KR20220097434A/ko active Pending
- 2020-10-30 CN CN202080091908.1A patent/CN114929345B/zh active Active
- 2020-10-30 EP EP20811872.9A patent/EP4051388A1/en active Pending
- 2020-10-30 US US17/773,425 patent/US20230117470A1/en active Pending
- 2020-10-30 WO PCT/US2020/058081 patent/WO2021087181A1/en not_active Ceased
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