JP2023501443A5 - - Google Patents

Info

Publication number
JP2023501443A5
JP2023501443A5 JP2022526463A JP2022526463A JP2023501443A5 JP 2023501443 A5 JP2023501443 A5 JP 2023501443A5 JP 2022526463 A JP2022526463 A JP 2022526463A JP 2022526463 A JP2022526463 A JP 2022526463A JP 2023501443 A5 JP2023501443 A5 JP 2023501443A5
Authority
JP
Japan
Prior art keywords
cell
cell culture
decreasing
increasing
molecular properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022526463A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023501443A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/059818 external-priority patent/WO2021096850A1/en
Publication of JP2023501443A publication Critical patent/JP2023501443A/ja
Publication of JP2023501443A5 publication Critical patent/JP2023501443A5/ja
Priority to JP2025234526A priority Critical patent/JP2026041907A/ja
Pending legal-status Critical Current

Links

JP2022526463A 2019-11-11 2020-11-10 自動化された細胞処理のための品質制御方法 Pending JP2023501443A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025234526A JP2026041907A (ja) 2019-11-11 2025-12-05 自動化された細胞処理のための品質制御方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962933575P 2019-11-11 2019-11-11
US62/933,575 2019-11-11
PCT/US2020/059818 WO2021096850A1 (en) 2019-11-11 2020-11-10 Quality control methods for automated cell processing

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025234526A Division JP2026041907A (ja) 2019-11-11 2025-12-05 自動化された細胞処理のための品質制御方法

Publications (2)

Publication Number Publication Date
JP2023501443A JP2023501443A (ja) 2023-01-18
JP2023501443A5 true JP2023501443A5 (enExample) 2023-11-20

Family

ID=75908887

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022526463A Pending JP2023501443A (ja) 2019-11-11 2020-11-10 自動化された細胞処理のための品質制御方法
JP2025234526A Pending JP2026041907A (ja) 2019-11-11 2025-12-05 自動化された細胞処理のための品質制御方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025234526A Pending JP2026041907A (ja) 2019-11-11 2025-12-05 自動化された細胞処理のための品質制御方法

Country Status (8)

Country Link
US (2) US12163146B2 (enExample)
EP (1) EP4058563A4 (enExample)
JP (2) JP2023501443A (enExample)
KR (1) KR20220097457A (enExample)
CN (1) CN114667341A (enExample)
CA (1) CA3159567A1 (enExample)
IL (1) IL292846A (enExample)
WO (1) WO2021096850A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12252678B2 (en) 2021-12-01 2025-03-18 Microfluidx Ltd Systems and methods for bioprocessing
US20250215382A1 (en) * 2023-12-31 2025-07-03 Trenchant BioSystems, Inc. Functionally closed cell processing system

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356794A (en) 1970-11-20 1974-06-12 Defence Secratary Of State For Apparatus and method for the production of a single cell suspen sion from tissue
IL68218A (en) 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
IL82746A (en) 1986-06-06 1994-10-07 Genentech Inc Process for producing biologically active tissue-type plasminogen activator
US5041138A (en) 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US6022742A (en) 1986-11-26 2000-02-08 Kopf; Henry B. Culture device and method
US5081036A (en) 1987-01-23 1992-01-14 Hoffmann-La Roche Inc. Method and apparatus for cell culture
EP0345588A1 (de) 1988-06-03 1989-12-13 Gesellschaft für Biotechnologische Forschung mbH (GBF) Verfahren und Anordnung zur Regelung eines biologischen Wachstumsprozesses
CA2000181A1 (en) 1988-10-14 1990-04-14 Chung-Faye Chao Process for producing cultured epidermal sheet, product and method of use
JPH02119772A (ja) 1988-10-29 1990-05-07 Shimadzu Corp 細胞培養装置
US4939151A (en) 1988-10-31 1990-07-03 Baxter International Inc. Adherent cell culture flask
US5240854A (en) 1989-06-05 1993-08-31 Berry Eric S Continuous high-density cell culture system
DE4021123A1 (de) 1989-10-07 1991-04-11 Sartorius Gmbh Fuer den laborbetrieb bestimmte vorrichtung zur behandlung fluessiger medien
WO1991005849A1 (en) 1989-10-10 1991-05-02 Aquasearch, Inc. Process and apparatus for the production of photosynthetic microbes
GB9010356D0 (en) 1990-05-09 1990-06-27 Ciba Geigy Ag Maturation of hemopoietic cells
CA2115140A1 (en) 1991-08-07 1993-02-18 Lola M. Reid Proliferation of hepatocyte precursors
JPH0654678A (ja) 1992-08-07 1994-03-01 Chuo Setsubi Eng Kk 微生物の自動流加培養法
DE4306661C2 (de) 1993-03-03 1995-04-20 Michael Dipl Biol Sittinger Verfahren zum Herstellen eines Implantates aus Zellkulturen
JP3453161B2 (ja) 1993-03-18 2003-10-06 宇宙開発事業団 液体培養ユニット
US5424209A (en) 1993-03-19 1995-06-13 Kearney; George P. Automated cell culture and testing system
US5478479A (en) 1994-05-20 1995-12-26 Haemonetics Corporation Two-stage cell wash process controlled by optical sensor
US5549134A (en) 1994-05-27 1996-08-27 Marcvalve Corporation Diaphragm valve
JP3549949B2 (ja) 1994-06-17 2004-08-04 山陽電子工業株式会社 低酸素培養器
US6297046B1 (en) 1994-10-28 2001-10-02 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US5792603A (en) 1995-04-27 1998-08-11 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts
US6121042A (en) 1995-04-27 2000-09-19 Advanced Tissue Sciences, Inc. Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs
US5846828A (en) 1995-06-07 1998-12-08 Advanced Tissue Sciences Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing tissue, synthetic, or mechanical heart valves orvalve segments
AU5931896A (en) 1995-06-07 1996-12-30 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs
US5728581A (en) 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
US6238908B1 (en) 1995-06-07 2001-05-29 Aastrom Biosciences, Inc. Apparatus and method for maintaining and growth biological cells
US6096532A (en) 1995-06-07 2000-08-01 Aastrom Biosciences, Inc. Processor apparatus for use in a system for maintaining and growing biological cells
US6228635B1 (en) 1995-06-07 2001-05-08 Aastrom Bioscience, Inc. Portable cell growth cassette for use in maintaining and growing biological cells
ES2162081T3 (es) 1995-06-07 2001-12-16 Aastrom Biosciences Inc Aparato y procedimiento para el mantenimiento y crecimiento de celulas biologicas.
US5688687A (en) 1995-06-07 1997-11-18 Aastrom Biosciences, Inc. Bioreactor for mammalian cell growth and maintenance
US5985653A (en) 1995-06-07 1999-11-16 Aastrom Biosciences, Inc. Incubator apparatus for use in a system for maintaining and growing biological cells
NZ315995A (en) 1995-09-01 1999-09-29 Millenium Biologix Inc Artificial sintered composition comprising stabilised calcium phosphate phases capable of supporting bone cell activity
DE69633189T2 (de) 1995-10-06 2005-08-11 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Fester Träger zur Verwendung in der Zellkultivierung, insbesondere für die Kultivierung von Leberzellen, Bioreaktor, welcher den festen Träger enthält, und die Verwendung davon in einem biologisch-künstlichen Lebersystem
AU1059997A (en) 1995-11-08 1997-05-29 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control
US5842477A (en) 1996-02-21 1998-12-01 Advanced Tissue Sciences, Inc. Method for repairing cartilage
US5827729A (en) 1996-04-23 1998-10-27 Advanced Tissue Sciences Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
ATE186235T1 (de) 1996-04-24 1999-11-15 Claude Fell Zelltrennungsvorrichtung für biologische flüssigkeiten wie blut
US6008010A (en) 1996-11-01 1999-12-28 University Of Pittsburgh Method and apparatus for holding cells
US6399375B2 (en) 1997-01-08 2002-06-04 Demtek A/S Method and apparatus for culturing cells and tissues
US5928936A (en) 1997-04-09 1999-07-27 Huntington Medical Research Institutes Cell culture container that self-seals after cannula penetration made of porous sheets
US5786207A (en) 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
US5922604A (en) 1997-06-05 1999-07-13 Gene Tec Corporation Thin reaction chambers for containing and handling liquid microvolumes
WO1999015629A1 (en) 1997-09-25 1999-04-01 Cytomatrix, Llc Methods and devices for the long-term culture of hematopoietic progenitor cells
EP1064353B1 (en) 1998-03-18 2002-11-06 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
US5882929A (en) 1998-04-07 1999-03-16 Tissue Engineering, Inc. Methods and apparatus for the conditioning of cartilage replacement tissue
US5989913A (en) 1998-07-02 1999-11-23 Charles Daniel Anderson Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using the same
MXPA01007820A (es) 1999-02-04 2003-06-19 Technion Res & Dev Foundation Metodo y aparato para mantenimiento y expansion de celulas de tallo hemopoyeticas y/o celulas progenitoras.
WO2001000783A2 (en) 1999-06-25 2001-01-04 Advanced Tissue Sciences, Inc. Monitorable three-dimensional scaffolds and tissue culture systems
US6632651B1 (en) 1999-07-06 2003-10-14 Ramot At Tel Aviv University Ltd. Tissue maintenance system that applies rhythmic pulses of pressure
US6402941B1 (en) 2000-02-07 2002-06-11 Wastewater Biological Solutions, Corp Apparatus for biological treatment of environmental contaminants and waste
JP3865354B2 (ja) 2000-03-02 2007-01-10 高木産業株式会社 細胞又は組織の培養方法
JP4402249B2 (ja) 2000-03-31 2010-01-20 正仁 田谷 細胞培養方法、細胞培養装置及び記録媒体
GB0009960D0 (en) 2000-04-25 2000-06-14 Oncoprobe Limited Electrochemical sensing
US7585323B2 (en) 2000-05-05 2009-09-08 Medlden, Llc In vitro mechanical loading of musculoskeletal tissues
US6485963B1 (en) 2000-06-02 2002-11-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof
US6673532B2 (en) 2000-08-14 2004-01-06 University Of Maryland, Baltimore County Bioreactor and bioprocessing technique
US6864084B2 (en) 2000-08-18 2005-03-08 Levitronix Llc Bioreactor and method for fluidly suspending a product
EP1325110A4 (en) 2000-10-02 2009-03-25 Thomas F Cannon AUTOMATED BIOCULTURE AND BIOCULTURAL EXPERIENCE SYSTEM
US20020146817A1 (en) 2000-10-02 2002-10-10 Cannon Thomas F. Automated bioculture and bioculture experiments system
DE10049437A1 (de) 2000-10-06 2002-04-25 Fraunhofer Ges Forschung Bioreaktor für die Kultivierung von Mikroorganismen sowie Verfahren zur Herstellung desselben
US7198940B2 (en) 2000-10-25 2007-04-03 Shot Hardware Optimization Technology, Inc. Bioreactor apparatus and cell culturing system
EP1355860A1 (en) 2001-01-09 2003-10-29 Wastewater Biological Solutions Corp. Apparatus and method for biological treatment of environmental contaminants and waste
FR2824071B1 (fr) 2001-04-26 2003-08-01 Cell Tissue Progress Dispositif de culture cellulaire et tissulaire a regulation thermique
US20050130297A1 (en) 2001-04-26 2005-06-16 Societe Nouvelle Cell Tissue Progress Cell and tissue culture device with temperature regulation
US7169578B2 (en) 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US6673595B2 (en) 2001-08-27 2004-01-06 Biocrystal, Ltd Automated cell management system for growth and manipulation of cultured cells
GB0121986D0 (en) 2001-09-11 2001-10-31 Isis Innovation Method and structure for growing living organic tissue
US7348175B2 (en) 2002-03-15 2008-03-25 St3 Development Corporation Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products
US8492140B2 (en) 2002-04-08 2013-07-23 Octane Biotech Inc. Automated tissue engineering system
US20030215935A1 (en) 2002-05-14 2003-11-20 Coon David James Apparatus and method for isolating living cells from an encapsulated organ tissue sample
EP1649056A1 (en) 2003-07-02 2006-04-26 Caliper Life Sciences, Inc. Methods for amplifying and detecting nucleic acids in microfluidic devices under continuous and non-continuous flow conditions.
EP2997134B1 (en) 2013-05-14 2020-06-24 Board of Regents, The University of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
KR20240164967A (ko) 2014-02-04 2024-11-21 카이트 파마 인코포레이티드 B 세포 악성종양 및 다른 암을 치료하는데 유용한 자가 t 세포 및 그의 조성물의 생산 방법
IL292038B2 (en) 2014-04-23 2024-12-01 Juno Therapeutics Inc Methods for enriching or producing immune cell populations for adoptive therapy
JP6661544B2 (ja) * 2014-04-24 2020-03-11 ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング 遺伝子改変したt細胞の自動生成法
CN106456670B (zh) 2014-04-25 2020-01-07 蓝鸟生物公司 制备过继性细胞疗法的改善方法
EP3217989B1 (en) 2014-10-31 2022-01-05 The Trustees of the University of Pennsylvania Compositions and methods of stimulating and expanding t cells
JP6740234B2 (ja) 2014-11-05 2020-08-12 ジュノー セラピューティクス インコーポレイテッド 形質導入および細胞プロセシングのための方法
RU2751362C2 (ru) 2014-12-29 2021-07-13 Новартис Аг Способы получения экспрессирующих химерный антигенный рецептор клеток
US10350245B2 (en) 2015-01-21 2019-07-16 Fred Hutchinson Cancer Research Center Point-of-care and/or portable platform for gene therapy
US11608511B2 (en) 2015-04-13 2023-03-21 Maxcyte, Inc. Methods for modifying genomic DNA
GB201508752D0 (en) 2015-05-21 2015-07-01 Mason Christopher And Veraitch Farlan S Cell culture device, system and methods of use thereof
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
CN109923204A (zh) 2016-07-21 2019-06-21 塞尔艾德 用于细胞的自动化独立并行批量处理的方法和装置
CA3034452A1 (en) 2016-08-21 2018-03-01 Adva Biotechnology Ltd. Bioreactor and methods of use thereof
EP3571294A1 (en) 2017-01-18 2019-11-27 F1 Oncology, Inc. Methods of transducing and expanding immune cells and uses thereof
US12054733B2 (en) 2017-06-16 2024-08-06 Lonza Ltd Universal self-regulating mammalian cell line platform for the production of biologics
MX2019015505A (es) * 2017-06-30 2020-07-28 Inscripta Inc Metodos, modulos, instrumentos y sistemas de procesamiento de celulas automatizados.
KR102546681B1 (ko) * 2017-09-01 2023-06-22 론차 콜로그네 게엠베하 엔드-투-엔드 세포 요법의 자동화
EP3841193A1 (en) 2018-08-21 2021-06-30 Lonza Ltd. A process for creating reference data for predicting concentrations of quality attributes

Similar Documents

Publication Publication Date Title
KR102768263B1 (ko) Nk 세포 형질도입 방법
JP2025031794A5 (enExample)
JP2023060000A (ja) レトロウイルスおよびレンチウイルスベクター
ES2973087T3 (es) Proteína de fusión para la utilización en el tratamiento de la enfermedad EHIC
IL315340A (en) End-to-end cell therapy automation
US11421287B2 (en) Methods for assessing the presence or absence of replication competent virus
CN104788573B (zh) 嵌合抗原受体hCD19scFv-CD8α-CD28-CD3ζ及其用途
CN110818803B (zh) 分泌表达il15ra-il15融合蛋白、ccl21趋化因子的嵌合抗原受体-t细胞及应用
CN109504660B (zh) 一种第四代car-t细胞及其构建方法和应用
US20170145106A1 (en) Chimeric antigen receptor hCD87-CAR and applications thereof
JP2022526372A (ja) HvG疾患の処置における使用のためのCAR
CN115925948B (zh) 一种抗cd22纳米抗体及其应用
JP2022191501A (ja) 多能性幹細胞からヘルパーt細胞を製造する方法
CN113121676A (zh) 一种靶向巨细胞病毒抗原的特异性t细胞受体及其应用
JP2025066794A (ja) 遺伝子改変自己t細胞を製造するためのプロセス
CN111484559A (zh) 第三代nkg2d嵌合抗原受体t或nk细胞的构建及应用
CN112391349A (zh) 滋养层细胞株及其制备方法和体外诱导扩增nk细胞的方法
CN111983218A (zh) 一种用于检测活细胞-活细胞表面受体-配体相互作用的试剂盒
CN117143823B (zh) 一种基于tcr单链可变区的靶向ras(g12v)的嵌合抗原受体记忆nk细胞的研制及其应用
JP2023501443A (ja) 自動化された細胞処理のための品質制御方法
CN117447604A (zh) 靶向c-Met的嵌合抗原受体及应用
JP2023530419A5 (enExample)
Muñoz et al. Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells
CN113736810A (zh) 构建体、载体、蛋白、细胞、制备方法、产品及应用
CN117069856B (zh) 双特异性抗体及应用、组合物、激活和扩增t细胞的方法