JP2023500875A5 - - Google Patents

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Publication number
JP2023500875A5
JP2023500875A5 JP2022525715A JP2022525715A JP2023500875A5 JP 2023500875 A5 JP2023500875 A5 JP 2023500875A5 JP 2022525715 A JP2022525715 A JP 2022525715A JP 2022525715 A JP2022525715 A JP 2022525715A JP 2023500875 A5 JP2023500875 A5 JP 2023500875A5
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JP
Japan
Prior art keywords
seq
antibody
cancer
drug conjugate
amino acid
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Granted
Application number
JP2022525715A
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English (en)
Japanese (ja)
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JP7657213B2 (ja
JP2023500875A (ja
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Priority claimed from PCT/IB2020/000917 external-priority patent/WO2021090062A1/en
Publication of JP2023500875A publication Critical patent/JP2023500875A/ja
Publication of JP2023500875A5 publication Critical patent/JP2023500875A5/ja
Application granted granted Critical
Publication of JP7657213B2 publication Critical patent/JP7657213B2/ja
Active legal-status Critical Current
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JP2022525715A 2019-11-07 2020-11-06 抗メソテリンエリブリン抗体-薬物コンジュゲート及び使用方法 Active JP7657213B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962932373P 2019-11-07 2019-11-07
US62/932,373 2019-11-07
PCT/IB2020/000917 WO2021090062A1 (en) 2019-11-07 2020-11-06 Anti-mesothelin eribulin antibody-drug conjugates and methods of use

Publications (3)

Publication Number Publication Date
JP2023500875A JP2023500875A (ja) 2023-01-11
JP2023500875A5 true JP2023500875A5 (https=) 2023-11-08
JP7657213B2 JP7657213B2 (ja) 2025-04-04

Family

ID=73943294

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022525715A Active JP7657213B2 (ja) 2019-11-07 2020-11-06 抗メソテリンエリブリン抗体-薬物コンジュゲート及び使用方法

Country Status (17)

Country Link
US (2) US11572414B2 (https=)
EP (1) EP4055053A1 (https=)
JP (1) JP7657213B2 (https=)
KR (1) KR20220095197A (https=)
CN (1) CN114729042B (https=)
AU (1) AU2020380603A1 (https=)
BR (1) BR112022008756A2 (https=)
CA (1) CA3159541A1 (https=)
CO (1) CO2022007924A2 (https=)
IL (1) IL291643A (https=)
JO (1) JOP20220070A1 (https=)
MX (1) MX2022005221A (https=)
MY (1) MY209745A (https=)
PE (1) PE20230467A1 (https=)
PH (1) PH12022551036A1 (https=)
TW (1) TWI877249B (https=)
WO (1) WO2021090062A1 (https=)

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Publication number Priority date Publication date Assignee Title
EP3801523B1 (en) 2018-06-01 2024-09-11 Eisai R&D Management Co., Ltd. Splicing modulators
CN119405832A (zh) 2018-06-01 2025-02-11 卫材R&D管理有限公司 剪接调节抗体-药物缀合物及其使用方法
SG11202102419VA (en) 2018-12-13 2021-04-29 Eisai R&D Man Co Ltd Herboxidiene splicing modulator antibody-drug conjugates and methods of use
WO2021090062A1 (en) 2019-11-07 2021-05-14 Eisai R&D Management Co., Ltd. Anti-mesothelin eribulin antibody-drug conjugates and methods of use
AU2021284401A1 (en) 2020-06-05 2023-01-05 Eisai R&D Management Co., Ltd. Anti-BCMA antibody-drug conjugates and methods of use
CA3225975A1 (en) * 2021-07-22 2023-01-26 Shanghai Senhui Medicine Co., Ltd. Drug conjugate of eribulin derivative
WO2023016488A1 (zh) * 2021-08-13 2023-02-16 昆山新蕴达生物科技有限公司 一种基于微管抑制剂的抗体偶联药物
JP2024533356A (ja) * 2021-09-16 2024-09-12 チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド 抗her3抗体薬物複合体及びその組成物並びに用途
TW202321296A (zh) 2021-10-06 2023-06-01 美商鏈接免疫療法公司 抗間皮素抗原結合分子及其用途
TW202518024A (zh) 2023-10-13 2025-05-01 日商衛材R&D企管股份有限公司 抗體-藥物軛合物代謝物
US20260048137A1 (en) * 2024-08-16 2026-02-19 Ardeagen Corporation Anti-mesothelin antibody conjugates and methods of use thereof

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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4880078A (en) 1987-06-29 1989-11-14 Honda Giken Kogyo Kabushiki Kaisha Exhaust muffler
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CA2109528A1 (en) 1991-05-01 1992-11-02 Gregory A. Prince A method for treating infectious respiratory diseases
US5934272A (en) 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US6019968A (en) 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
ATE508733T1 (de) 1996-03-04 2011-05-15 Penn State Res Found Materialien und verfahren zur steigerung der zellulären internalisierung
US5855913A (en) 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
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JP4454151B2 (ja) 1998-06-17 2010-04-21 エーザイ・アール・アンド・ディー・マネジメント株式会社 大環状類似体及びそれらの使用並びに調製方法
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CN104955845B (zh) * 2012-09-27 2018-11-16 美国政府(由卫生和人类服务部的部长所代表) 间皮素抗体和引起有效的抗肿瘤活性的方法
US10294304B2 (en) * 2015-04-13 2019-05-21 Pfizer Inc. Chimeric antigen receptors targeting B-cell maturation antigen
SMT202000633T1 (it) 2015-06-19 2021-01-05 Eisai R&D Man Co Ltd Immunoglobuline coniugate a cys80
UA124622C2 (uk) 2015-12-18 2021-10-20 ЕЙСАЙ Ар ЕНД Ді МЕНЕДЖМЕНТ КО., ЛТД. Кон'юговані імуноглобуліни з c-кінцевим лізином
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PE20231050A1 (es) * 2016-03-02 2023-07-11 Eisai Randd Man Co Ltd Conjugados de anticuerpo y farmaco basados en eribulina y metodos para su uso
CN119405832A (zh) 2018-06-01 2025-02-11 卫材R&D管理有限公司 剪接调节抗体-药物缀合物及其使用方法
SG11202102419VA (en) 2018-12-13 2021-04-29 Eisai R&D Man Co Ltd Herboxidiene splicing modulator antibody-drug conjugates and methods of use
WO2021090062A1 (en) 2019-11-07 2021-05-14 Eisai R&D Management Co., Ltd. Anti-mesothelin eribulin antibody-drug conjugates and methods of use
JP7821733B2 (ja) 2020-01-22 2026-02-27 上海森輝医薬有限公司 エリブリン誘導体の薬物複合体、その調製方法及びその医薬的応用
AU2021284401A1 (en) 2020-06-05 2023-01-05 Eisai R&D Management Co., Ltd. Anti-BCMA antibody-drug conjugates and methods of use

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