|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US7413537B2
(en)
|
1989-09-01 |
2008-08-19 |
Dyax Corp. |
Directed evolution of disulfide-bonded micro-proteins
|
|
DK1621554T4
(da)
|
1992-08-21 |
2012-12-17 |
Univ Bruxelles |
Immunoglobuliner blottet for lette kæder
|
|
ES2162863T3
(es)
|
1993-04-29 |
2002-01-16 |
Unilever Nv |
Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
|
|
FR2708622B1
(fr)
|
1993-08-02 |
1997-04-18 |
Raymond Hamers |
Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides.
|
|
EP0739981A1
(en)
|
1995-04-25 |
1996-10-30 |
Vrije Universiteit Brussel |
Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
|
|
US6113898A
(en)
|
1995-06-07 |
2000-09-05 |
Idec Pharmaceuticals Corporation |
Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
ES2294799T3
(es)
|
1996-06-27 |
2008-04-01 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. |
Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana.
|
|
AU3596599A
(en)
|
1998-01-26 |
1999-08-09 |
Unilever Plc |
Method for producing antibody fragments
|
|
EP1141711A1
(en)
|
1999-01-05 |
2001-10-10 |
Unilever Plc |
Binding of antibody fragments to solid supports
|
|
DK1144616T4
(da)
|
1999-01-19 |
2009-03-30 |
Unilever Nv |
Fremgangsmåde til fremstilling af antistoffragmenter
|
|
HK1048138B
(zh)
|
1999-04-15 |
2009-06-12 |
荷兰克鲁塞尔公司 |
用编码腺病毒e1蛋白的序列在人体细胞中生产重组蛋白
|
|
CA2370351A1
(en)
|
1999-04-22 |
2000-11-02 |
Unilever Plc |
Inhibition of viral infection using monovalent antigen-binding proteins
|
|
ATE421976T1
(de)
|
1999-05-18 |
2009-02-15 |
Dyax Corp |
Fab fragmentbibliotheken und verfahren für deren verwendung
|
|
US6479280B1
(en)
|
1999-09-24 |
2002-11-12 |
Vlaams Interuniversitair Institutuut Voor Biotechnologie Vzw |
Recombinant phages capable of entering host cells via specific interaction with an artificial receptor
|
|
ES2331051T3
(es)
|
1999-11-29 |
2009-12-21 |
Bac Ip B.V. |
Inmovilizacion de moleculas de union de antigenos de un dominio.
|
|
WO2001040310A2
(en)
|
1999-11-29 |
2001-06-07 |
Unilever Plc |
Immobilisation of proteins using a polypeptide segment
|
|
ES2324280T3
(es)
|
2000-03-14 |
2009-08-04 |
Unilever N.V. |
Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos.
|
|
US20030190598A1
(en)
|
2000-05-26 |
2003-10-09 |
Jasmid Tanha |
Single-domain antigen-binding antibody fragments derived from llama antibodies
|
|
US7083784B2
(en)
|
2000-12-12 |
2006-08-01 |
Medimmune, Inc. |
Molecules with extended half-lives, compositions and uses thereof
|
|
ATE513854T1
(de)
|
2000-12-13 |
2011-07-15 |
Bac Ip B V |
Proteinraster aus variablen domänen der schweren immunoglobulinkette von kamelen
|
|
US20060073141A1
(en)
|
2001-06-28 |
2006-04-06 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
|
JP4213586B2
(ja)
|
2001-09-13 |
2009-01-21 |
株式会社抗体研究所 |
ラクダ抗体ライブラリーの作製方法
|
|
JP2005289809A
(ja)
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
|
EP1456410A2
(en)
|
2001-12-11 |
2004-09-15 |
AlgoNomics N.V. |
Method for displaying loops from immunoglobulin domains in different contexts
|
|
EP1456237A2
(en)
|
2001-12-21 |
2004-09-15 |
Vlaams Interuniversitair Instituut voor Biotechnologie vzw. |
Method for cloning of variable domain sequences
|
|
CA2471645A1
(en)
|
2002-01-03 |
2003-07-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Immunoconjugates useful for treatment of tumours
|
|
WO2004041863A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against interferon- gamma and uses therefor
|
|
EP1558645B1
(en)
|
2002-11-08 |
2011-07-27 |
Ablynx N.V. |
Stabilized single domain antibodies in pharmaceutical composition adapted for inhalation
|
|
JP2006517789A
(ja)
|
2003-01-10 |
2006-08-03 |
アブリンクス エン.ヴェー. |
治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用
|
|
EP1656128A4
(en)
|
2003-08-12 |
2007-02-28 |
William M Yarbrough |
SINGLE ACNE TREATMENT AND METHOD OF USE
|
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
US8044019B2
(en)
|
2005-10-28 |
2011-10-25 |
Mitsubishi Tanabe Pharma Corporation |
Cell penetrating peptide
|
|
WO2009021548A1
(en)
|
2007-08-10 |
2009-02-19 |
Wacker Chemie Ag |
Expression of full length igg and secretion into the culture medium of prokaryotic cells
|
|
WO2009147368A1
(en)
|
2008-06-04 |
2009-12-10 |
Medical Research Council |
Peptides
|
|
GB2476681B
(en)
|
2010-01-04 |
2012-04-04 |
Argen X Bv |
Humanized camelid VH, VK and VL immunoglobulin domains
|
|
US8372951B2
(en)
|
2010-05-14 |
2013-02-12 |
National Tsing Hua University |
Cell penetrating peptides for intracellular delivery
|
|
GB201106395D0
(en)
*
|
2011-04-14 |
2011-06-01 |
Hubrecht Inst |
Compounds
|
|
US8614194B1
(en)
|
2012-07-25 |
2013-12-24 |
Kaohsiung Medical University |
Anionic cell penetrating peptide and its use for intracellular delivery
|