JP2023106433A5 - - Google Patents

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Publication number
JP2023106433A5
JP2023106433A5 JP2023075458A JP2023075458A JP2023106433A5 JP 2023106433 A5 JP2023106433 A5 JP 2023106433A5 JP 2023075458 A JP2023075458 A JP 2023075458A JP 2023075458 A JP2023075458 A JP 2023075458A JP 2023106433 A5 JP2023106433 A5 JP 2023106433A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023075458A
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English (en)
Japanese (ja)
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JP2023106433A (ja
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Publication date
Priority claimed from JP2020505208A external-priority patent/JP2020529410A/ja
Application filed filed Critical
Publication of JP2023106433A publication Critical patent/JP2023106433A/ja
Publication of JP2023106433A5 publication Critical patent/JP2023106433A5/ja
Priority to JP2025092507A priority Critical patent/JP2025131681A/ja
Pending legal-status Critical Current

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JP2023075458A 2017-07-31 2023-05-01 Nkg2d、cd16及びflt3と結合するタンパク質 Pending JP2023106433A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025092507A JP2025131681A (ja) 2017-07-31 2025-06-03 Nkg2d、cd16及びflt3と結合するタンパク質

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762539421P 2017-07-31 2017-07-31
US62/539,421 2017-07-31
JP2020505208A JP2020529410A (ja) 2017-07-31 2018-07-31 Nkg2d、cd16及びflt3と結合するタンパク質

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020505208A Division JP2020529410A (ja) 2017-07-31 2018-07-31 Nkg2d、cd16及びflt3と結合するタンパク質

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025092507A Division JP2025131681A (ja) 2017-07-31 2025-06-03 Nkg2d、cd16及びflt3と結合するタンパク質

Publications (2)

Publication Number Publication Date
JP2023106433A JP2023106433A (ja) 2023-08-01
JP2023106433A5 true JP2023106433A5 (https=) 2023-12-01

Family

ID=65233032

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020505208A Pending JP2020529410A (ja) 2017-07-31 2018-07-31 Nkg2d、cd16及びflt3と結合するタンパク質
JP2023075458A Pending JP2023106433A (ja) 2017-07-31 2023-05-01 Nkg2d、cd16及びflt3と結合するタンパク質
JP2025092507A Pending JP2025131681A (ja) 2017-07-31 2025-06-03 Nkg2d、cd16及びflt3と結合するタンパク質

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020505208A Pending JP2020529410A (ja) 2017-07-31 2018-07-31 Nkg2d、cd16及びflt3と結合するタンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025092507A Pending JP2025131681A (ja) 2017-07-31 2025-06-03 Nkg2d、cd16及びflt3と結合するタンパク質

Country Status (15)

Country Link
US (1) US20200165344A1 (https=)
EP (1) EP3661554A4 (https=)
JP (3) JP2020529410A (https=)
KR (2) KR20200033302A (https=)
CN (1) CN111132698A (https=)
AU (2) AU2018309712A1 (https=)
BR (1) BR112020001972A2 (https=)
CA (1) CA3070986A1 (https=)
CO (1) CO2020001981A2 (https=)
EA (1) EA202090387A1 (https=)
IL (1) IL272374A (https=)
MA (1) MA49769A (https=)
MX (1) MX2020001257A (https=)
SG (1) SG11202000632QA (https=)
WO (1) WO2019028027A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018219887B2 (en) 2017-02-08 2024-08-15 Dragonfly Therapeutics, LLC Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
CN110944661A (zh) 2017-02-20 2020-03-31 蜻蜓疗法股份有限公司 结合her2、nkg2d和cd16的蛋白质
CA3237846A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
BR112020015994A2 (pt) 2018-02-08 2020-12-15 Dragonfly Therapeutics, Inc. Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer
WO2019164930A1 (en) 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
JOP20200234A1 (ar) 2018-03-27 2020-09-15 Xyphos Biosciences Inc نطاقات a1-a2 معدلة لمركبات ترابطية nkg2d غير طبيعية ترتبط بمستقبلات nkg2d غير طبيعية.
EP3833392A4 (en) 2018-08-08 2022-05-18 Dragonfly Therapeutics, Inc. MULTISPECIFIC BINDING PROTEINS FOR BINDING CD33, NKG2D AND CD16 AND METHODS OF USE
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
KR102835308B1 (ko) 2018-08-08 2025-07-21 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
SG11202104352XA (en) 2018-12-18 2021-05-28 Boehringer Ingelheim Io Canada Inc Flt3 agonist antibodies and uses thereof
PE20221316A1 (es) * 2019-10-15 2022-09-07 Dragonfly Therapeutics Inc Proteinas que se unen a nkg2d, cd16 y flt3
CN115768463A (zh) * 2020-02-21 2023-03-07 哈普恩治疗公司 Flt3结合蛋白及使用方法
JP7512394B2 (ja) 2020-05-06 2024-07-08 ドラゴンフライ セラピューティクス, インコーポレイテッド Nkg2d、cd16及びclec12aに結合するタンパク質
EP4301774A4 (en) 2021-03-03 2025-08-13 Dragonfly Therapeutics Inc METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN
WO2023274183A1 (zh) * 2021-06-29 2023-01-05 江苏先声药业有限公司 Cd16抗体及其应用
WO2026052582A1 (en) 2024-09-04 2026-03-12 Red Ridge Bio Ag Biparatopic antibodies that specifically bind fms related receptor tyrosine kinase 3

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008337517B2 (en) * 2007-12-14 2014-06-26 Novo Nordisk A/S Antibodies against human NKG2D and uses thereof
AR071891A1 (es) * 2008-05-30 2010-07-21 Imclone Llc Anticuerpos humanos anti-flt3 (receptor tirosina cinasa 3 tipo fms humano)
UY32808A (es) * 2009-07-29 2011-02-28 Abbott Lab Inmunoglobulinas como dominio variable dual y usos de las mismas
DK2516468T3 (en) * 2009-12-23 2016-05-23 Synimmune Gmbh ANTI-FLT3 ANTIBODIES AND METHODS FOR USING THESE
UY33492A (es) * 2010-07-09 2012-01-31 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
HUE033245T2 (hu) * 2011-12-19 2017-11-28 Synimmune Gmbh Bispecifikus ellenanyag molekula
JP6628966B2 (ja) * 2012-06-14 2020-01-15 中外製薬株式会社 改変されたFc領域を含む抗原結合分子
EP4050026A1 (en) * 2014-04-01 2022-08-31 Adimab, LLC Method of obtaining or identifying one or more common light chains for use in preparing a multispecific antibody
WO2016166139A1 (en) * 2015-04-14 2016-10-20 Eberhard Karls Universität Tübingen Bispecific fusion proteins for enhancing immune responses of lymphocytes against tumor cells

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