JP2020507577A5 - - Google Patents
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- Publication number
- JP2020507577A5 JP2020507577A5 JP2019543270A JP2019543270A JP2020507577A5 JP 2020507577 A5 JP2020507577 A5 JP 2020507577A5 JP 2019543270 A JP2019543270 A JP 2019543270A JP 2019543270 A JP2019543270 A JP 2019543270A JP 2020507577 A5 JP2020507577 A5 JP 2020507577A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- variable domain
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022074378A JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762457785P | 2017-02-10 | 2017-02-10 | |
| US62/457,785 | 2017-02-10 | ||
| PCT/US2018/017718 WO2018148610A1 (en) | 2017-02-10 | 2018-02-10 | Proteins binding psma, nkg2d and cd16 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022074378A Division JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020507577A JP2020507577A (ja) | 2020-03-12 |
| JP2020507577A5 true JP2020507577A5 (https=) | 2021-03-25 |
Family
ID=63107819
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543270A Withdrawn JP2020507577A (ja) | 2017-02-10 | 2018-02-10 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
| JP2022074378A Withdrawn JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022074378A Withdrawn JP2022105121A (ja) | 2017-02-10 | 2022-04-28 | Ｐｓｍａ、ｎｋｇ２ｄおよびｃｄ１６に結合するタンパク質 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20200024353A1 (https=) |
| EP (1) | EP3579878A4 (https=) |
| JP (2) | JP2020507577A (https=) |
| KR (1) | KR20190120770A (https=) |
| CN (1) | CN110913902A (https=) |
| AU (1) | AU2018217834A1 (https=) |
| BR (1) | BR112019016553A2 (https=) |
| CA (1) | CA3053275A1 (https=) |
| IL (1) | IL268574A (https=) |
| MX (1) | MX2019009541A (https=) |
| RU (1) | RU2019128204A (https=) |
| SG (1) | SG11201907271PA (https=) |
| WO (1) | WO2018148610A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201907299XA (en) | 2017-02-08 | 2019-09-27 | Dragonfly Therapeutics Inc | Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer |
| IL268755B2 (en) | 2017-02-20 | 2025-12-01 | Dragonfly Therapeutics Inc | Proteins that bind her2, nkg2d, and cd16 |
| EA202091887A1 (ru) | 2018-02-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Комбинированная терапия рака с применением мультиспецифических связывающих белков, которые активируют естественные клетки-киллеры |
| DK3749346T3 (da) | 2018-02-08 | 2024-09-09 | Dragonfly Therapeutics Inc | Antistof variable domænekombinationer rettet mod nkg2d-receptoren |
| WO2019164930A1 (en) | 2018-02-20 | 2019-08-29 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use |
| WO2020033630A1 (en) | 2018-08-08 | 2020-02-13 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| US12378318B2 (en) | 2018-08-08 | 2025-08-05 | Dragonfly Therapeutics, Inc. | Proteins binding NKG2D, CD16 and a tumor-associated antigen |
| MX2022013944A (es) | 2020-05-06 | 2022-11-30 | Dragonfly Therapeutics Inc | Proteinas que se unen al receptor activador de celulas asesinas naturales grupo 2 miembro d (nkg2d), cumulo de diferenciacion (cd16) y miembro a de la familia de dominios de lectina tipo c 12 (clec12a). |
| JP2024508894A (ja) | 2021-03-03 | 2024-02-28 | ドラゴンフライ セラピューティクス， インコーポレイテッド | Ｎｋｇ２ｄ、ｃｄ１６、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法 |
| CN117881702A (zh) * | 2021-08-03 | 2024-04-12 | 山东先声生物制药有限公司 | 一种cd16抗体及其应用 |
| CN117915950A (zh) * | 2021-08-06 | 2024-04-19 | 甘李药业股份有限公司 | 一种多特异性抗体及其用途 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1423700A (zh) * | 2000-03-24 | 2003-06-11 | 麦克美特股份公司 | 含有针对nkg2d受体复合物的表位的结合位点的多功能多肽 |
| US6455712B1 (en) * | 2000-12-13 | 2002-09-24 | Shell Oil Company | Preparation of oxirane compounds |
| EP1909832A4 (en) * | 2005-06-29 | 2010-01-13 | Univ Miami | ANTIBODY IMMUNOCELL LIGAND FUSION PROTEIN FOR CANCER THERAPY |
| EP1945674A2 (en) * | 2005-11-03 | 2008-07-23 | Genentech, Inc. | Therapeutic anti-her2 antibody fusion polypeptides |
| WO2007146968A2 (en) * | 2006-06-12 | 2007-12-21 | Trubion Pharmaceuticals, Inc. | Single-chain multivalent binding proteins with effector function |
| KR101615935B1 (ko) * | 2007-12-14 | 2016-04-28 | 노보 노르디스크 에이/에스 | 인간 ｎｋｇ2ｄ에 대한 항체 및 그것의 용도 |
| US8629247B2 (en) * | 2009-04-14 | 2014-01-14 | Proscan Rx Pharma Inc. | Antibodies against prostate specific membrane antigen |
| UY32808A (es) * | 2009-07-29 | 2011-02-28 | Abbott Lab | Inmunoglobulinas como dominio variable dual y usos de las mismas |
| KR20130062264A (ko) * | 2010-04-15 | 2013-06-12 | 제넨테크, 인크. | 항-폴리유비퀴틴 항체 및 사용 방법 |
| UY33492A (es) * | 2010-07-09 | 2012-01-31 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| WO2012158818A2 (en) * | 2011-05-16 | 2012-11-22 | Fabion Pharmaceuticals, Inc. | Multi-specific fab fusion proteins and methods of use |
| US8852599B2 (en) * | 2011-05-26 | 2014-10-07 | Bristol-Myers Squibb Company | Immunoconjugates, compositions for making them, and methods of making and use |
| MX2014001238A (es) * | 2011-08-05 | 2014-09-22 | Genentech Inc | Anticuerpos contra poliubiquitina y métodos de uso. |
| US20140323315A1 (en) * | 2013-04-29 | 2014-10-30 | Adimab, Llc | Polyspecificity reagents, methods for their preparation and use |
| EP3152235B1 (en) * | 2014-05-29 | 2021-08-25 | MacroGenics, Inc. | Tri-specific binding molecules and methods of use thereof |
| MX2017006016A (es) * | 2014-11-11 | 2017-06-19 | Amunix Operating Inc | Composiciones conjugadas de xten direccionadas y metodos para producir las mismas. |
| SG11201705632UA (en) * | 2015-01-08 | 2017-08-30 | Kyowa Hakko Kirin Co Ltd | Bispecific antibody binding to trailr2 and psma |
| WO2016115274A1 (en) * | 2015-01-14 | 2016-07-21 | Compass Therapeutics Llc | Multispecific immunomodulatory antigen-binding constructs |
| CN107530424A (zh) * | 2015-02-20 | 2018-01-02 | 俄亥俄州国家创新基金会 | 针对nkg2d和肿瘤相关抗原的二价抗体 |
| WO2016135041A1 (en) * | 2015-02-26 | 2016-09-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Fusion proteins and antibodies comprising thereof for promoting apoptosis |
| RS61907B1 (sr) * | 2015-04-06 | 2021-06-30 | Subdomain Llc | Polipeptidi koji sadrže de novo vezujući domen i njihova primena |
| DK3313876T3 (da) * | 2015-06-23 | 2025-04-22 | Innate Pharma | Multispecifikke antigenbindende proteiner |
-
2018
- 2018-02-10 CA CA3053275A patent/CA3053275A1/en active Pending
- 2018-02-10 RU RU2019128204A patent/RU2019128204A/ru unknown
- 2018-02-10 WO PCT/US2018/017718 patent/WO2018148610A1/en not_active Ceased
- 2018-02-10 MX MX2019009541A patent/MX2019009541A/es unknown
- 2018-02-10 AU AU2018217834A patent/AU2018217834A1/en not_active Abandoned
- 2018-02-10 US US16/483,788 patent/US20200024353A1/en not_active Abandoned
- 2018-02-10 BR BR112019016553-3A patent/BR112019016553A2/pt not_active Application Discontinuation
- 2018-02-10 CN CN201880024146.6A patent/CN110913902A/zh active Pending
- 2018-02-10 EP EP18751484.9A patent/EP3579878A4/en not_active Withdrawn
- 2018-02-10 SG SG11201907271PA patent/SG11201907271PA/en unknown
- 2018-02-10 KR KR1020197026585A patent/KR20190120770A/ko not_active Withdrawn
- 2018-02-10 JP JP2019543270A patent/JP2020507577A/ja not_active Withdrawn
-
2019
- 2019-08-07 IL IL268574A patent/IL268574A/en unknown
-
2022
- 2022-04-28 JP JP2022074378A patent/JP2022105121A/ja not_active Withdrawn
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