JP2023071827A5 - - Google Patents
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- JP2023071827A5 JP2023071827A5 JP2023030635A JP2023030635A JP2023071827A5 JP 2023071827 A5 JP2023071827 A5 JP 2023071827A5 JP 2023030635 A JP2023030635 A JP 2023030635A JP 2023030635 A JP2023030635 A JP 2023030635A JP 2023071827 A5 JP2023071827 A5 JP 2023071827A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- pharmaceutical composition
- composition according
- disease
- glp1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024159697A JP7789871B2 (ja) | 2017-09-22 | 2024-09-17 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762562283P | 2017-09-22 | 2017-09-22 | |
| US62/562,283 | 2017-09-22 | ||
| PCT/US2018/052110 WO2019060653A1 (en) | 2017-09-22 | 2018-09-21 | GLP-1 RECEPTOR AGONISTS (GLUCAGON-LIKE PEPTIDE 1) AND USES THEREOF |
| JP2020516667A JP7239566B2 (ja) | 2017-09-22 | 2018-09-21 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020516667A Division JP7239566B2 (ja) | 2017-09-22 | 2018-09-21 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024159697A Division JP7789871B2 (ja) | 2017-09-22 | 2024-09-17 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023071827A JP2023071827A (ja) | 2023-05-23 |
| JP2023071827A5 true JP2023071827A5 (https=) | 2023-10-11 |
| JP7559112B2 JP7559112B2 (ja) | 2024-10-01 |
Family
ID=63799082
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020516667A Active JP7239566B2 (ja) | 2017-09-22 | 2018-09-21 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
| JP2023030635A Active JP7559112B2 (ja) | 2017-09-22 | 2023-03-01 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
| JP2024159697A Active JP7789871B2 (ja) | 2017-09-22 | 2024-09-17 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020516667A Active JP7239566B2 (ja) | 2017-09-22 | 2018-09-21 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024159697A Active JP7789871B2 (ja) | 2017-09-22 | 2024-09-17 | グルカゴン様ペプチド１受容体アゴニストおよびそれらの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US11045522B2 (https=) |
| EP (1) | EP3684793A1 (https=) |
| JP (3) | JP7239566B2 (https=) |
| KR (1) | KR102696518B1 (https=) |
| CN (2) | CN111108117B (https=) |
| AU (2) | AU2018338178B2 (https=) |
| CA (1) | CA3073964A1 (https=) |
| EA (1) | EA202090649A1 (https=) |
| IL (2) | IL273253B2 (https=) |
| MX (1) | MX2020002977A (https=) |
| MY (2) | MY200364A (https=) |
| SG (1) | SG11202001637PA (https=) |
| WO (1) | WO2019060653A1 (https=) |
| ZA (1) | ZA202001167B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3684793A1 (en) * | 2017-09-22 | 2020-07-29 | Regeneron Pharmaceuticals, Inc. | Glucagon-like peptide 1 receptor agonists and uses thereof |
| US12122817B2 (en) * | 2020-09-22 | 2024-10-22 | Serpentide Inc. | Long-lasting GLP1 analogue drug for type-2 diabetes |
| WO2022119076A1 (ko) * | 2020-12-03 | 2022-06-09 | 이뮤노포지 주식회사 | Glp-1 수용체 작용제 및 항-오스카 항체를 포함하는 융합 단백질 및 이의 용도 |
| WO2022117044A1 (en) * | 2020-12-03 | 2022-06-09 | Sunshine Lake Pharma Co., Ltd. | Glp-1/gcg dual receptor agonist polypeptide and fusion protein thereof |
| CN112716966B (zh) * | 2021-02-03 | 2022-05-03 | 浙江诺得药业有限公司 | 一种恩格列净药用组合物及其制备方法 |
| CN113461785B (zh) * | 2021-04-13 | 2022-10-14 | 湖南中晟全肽生化有限公司 | Glp-1受体激动剂及其应用 |
| CN119638849A (zh) * | 2021-10-18 | 2025-03-18 | 深圳科兴药业有限公司 | 一种生长激素融合蛋白及其应用 |
| CN114788876B (zh) * | 2022-02-24 | 2024-07-05 | 北京医院 | 治疗糖尿病的mRNA药物制剂及其制备方法与应用 |
| CN119497630A (zh) * | 2022-05-04 | 2025-02-21 | 免疫新炉有限公司 | 包含glp-1、免疫球蛋白fc和igf-1的融合蛋白及其用途 |
| WO2024123812A1 (en) | 2022-12-05 | 2024-06-13 | Shattuck Labs, Inc. | Fusion proteins for the treatment of cardiometabolic diseases |
| CN117143242B (zh) * | 2023-10-30 | 2024-03-29 | 南京佰抗生物科技有限公司 | 抗Galectin-3蛋白的单克隆抗体组合物及应用 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| US20250270274A1 (en) * | 2024-02-26 | 2025-08-28 | Serpentide Inc. | Super long-lasting glp1 or glp1/gip analogue drug for type-2 diabetes and obesity |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1641823T3 (da) | 2003-06-12 | 2011-12-12 | Lilly Co Eli | GLP-1-analog fusionsproteiner |
| US8257740B1 (en) | 2011-08-15 | 2012-09-04 | Gp Medical, Inc. | Pharmaceutical composition of nanoparticles |
| US20060275288A1 (en) | 2005-01-20 | 2006-12-07 | Grihalde Nelson D | GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof |
| US8246995B2 (en) | 2005-05-10 | 2012-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells |
| US8497240B2 (en) | 2006-08-17 | 2013-07-30 | Amylin Pharmaceuticals, Llc | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
| AR064623A1 (es) | 2006-12-21 | 2009-04-15 | Centocor Inc | Uso de agonistas del receptor de glp -1 de accion prolongada para mejorar la sensibilidad a la insulina y los perfiles lipidicos |
| US20110034373A1 (en) | 2007-08-03 | 2011-02-10 | Eli Lilly And Company | Use of an fgf-21 compound and a glp-1 compound for the treatment of obesity |
| EP2190872B1 (en) | 2007-09-05 | 2018-03-14 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| PT2373681T (pt) | 2008-12-10 | 2017-04-11 | Glaxosmithkline Llc | Composições farmacêuticas de albiglutida |
| US20120148586A1 (en) | 2009-08-27 | 2012-06-14 | Joyce Ching Tsu Chou | Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders |
| WO2011043530A1 (ko) * | 2009-10-09 | 2011-04-14 | (주)알테오젠 | Ｇｌｐ-1 유사체의 융합체, 및 이를 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 조성물 |
| ES2617281T3 (es) | 2009-10-28 | 2017-06-16 | Janssen Biotech, Inc. | Anticuerpos anti-glp-1r y sus usos |
| EP2496249B1 (en) | 2009-11-03 | 2016-03-09 | Amylin Pharmaceuticals, LLC | Glp-1 receptor agonist for use in treating obstructive sleep apnea |
| JP2015533483A (ja) | 2012-09-07 | 2015-11-26 | サノフイ | メタボリックシンドロームを治療するための融合タンパク質 |
| AU2014207748B2 (en) | 2013-01-17 | 2018-10-11 | Vtv Therapeutics Llc | Combinations of a GLP1R agonist and metformin and use thereof for the treatment of type 2 diabetes and other disorders |
| US20150259416A1 (en) | 2014-03-12 | 2015-09-17 | Biocrine Ab | Methods for treating and/or limiting development of diabetes |
| CN104371019B (zh) | 2013-08-13 | 2019-09-10 | 鸿运华宁（杭州）生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
| CN104098702B (zh) * | 2014-07-23 | 2017-06-16 | 湖北工业大学 | 一种利用mfh融合蛋白制备glp‑1多肽或其类似物方法和应用 |
| CN106397606B (zh) * | 2015-01-28 | 2020-11-10 | 中国科学院天津工业生物技术研究所 | 一种多肽复合物作为sst药物载体的应用、方法及其融合蛋白复合物 |
| PT3257524T (pt) | 2015-02-11 | 2020-11-27 | Gmax Biopharm Llc | Preparação de solução estabilizada de proteína de fusão de anticorpo glp-1r farmacêutica |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
| MX2018014966A (es) * | 2016-06-09 | 2019-08-14 | Medimmune Ltd | Peptidos monolipidados resistentes a proteasas. |
| EP3684793A1 (en) | 2017-09-22 | 2020-07-29 | Regeneron Pharmaceuticals, Inc. | Glucagon-like peptide 1 receptor agonists and uses thereof |
-
2018
- 2018-09-21 EP EP18783613.5A patent/EP3684793A1/en active Pending
- 2018-09-21 AU AU2018338178A patent/AU2018338178B2/en active Active
- 2018-09-21 IL IL273253A patent/IL273253B2/en unknown
- 2018-09-21 CA CA3073964A patent/CA3073964A1/en active Pending
- 2018-09-21 US US16/137,662 patent/US11045522B2/en active Active
- 2018-09-21 SG SG11202001637PA patent/SG11202001637PA/en unknown
- 2018-09-21 MX MX2020002977A patent/MX2020002977A/es unknown
- 2018-09-21 CN CN201880061327.6A patent/CN111108117B/zh active Active
- 2018-09-21 IL IL304574A patent/IL304574B2/en unknown
- 2018-09-21 MY MYPI2020000984A patent/MY200364A/en unknown
- 2018-09-21 EA EA202090649A patent/EA202090649A1/ru unknown
- 2018-09-21 JP JP2020516667A patent/JP7239566B2/ja active Active
- 2018-09-21 MY MYPI2023002759A patent/MY207828A/en unknown
- 2018-09-21 CN CN202410964216.3A patent/CN118955732A/zh active Pending
- 2018-09-21 KR KR1020207011414A patent/KR102696518B1/ko active Active
- 2018-09-21 WO PCT/US2018/052110 patent/WO2019060653A1/en not_active Ceased
-
2020
- 2020-02-25 ZA ZA2020/01167A patent/ZA202001167B/en unknown
-
2021
- 2021-05-27 US US17/332,215 patent/US11779633B2/en active Active
-
2023
- 2023-03-01 JP JP2023030635A patent/JP7559112B2/ja active Active
- 2023-08-29 US US18/457,482 patent/US12090193B2/en active Active
- 2023-09-04 AU AU2023223010A patent/AU2023223010B2/en active Active
-
2024
- 2024-08-14 US US18/804,421 patent/US20250000949A1/en active Pending
- 2024-09-17 JP JP2024159697A patent/JP7789871B2/ja active Active
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