JP2023021974A5 - - Google Patents

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Publication number
JP2023021974A5
JP2023021974A5 JP2022168571A JP2022168571A JP2023021974A5 JP 2023021974 A5 JP2023021974 A5 JP 2023021974A5 JP 2022168571 A JP2022168571 A JP 2022168571A JP 2022168571 A JP2022168571 A JP 2022168571A JP 2023021974 A5 JP2023021974 A5 JP 2023021974A5
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JP
Japan
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seq
domain
amino acid
acid sequence
cdr
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JP2022168571A
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Japanese (ja)
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JP2023021974A (ja
JP7612641B2 (ja
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Priority claimed from GBGB1610198.2A external-priority patent/GB201610198D0/en
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Priority to JP2024174078A priority Critical patent/JP2025011170A/ja
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JP2022168571A 2016-06-10 2022-10-20 抗IgE抗体 Active JP7612641B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024174078A JP2025011170A (ja) 2016-06-10 2024-10-03 抗IgE抗体

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB1610198.2A GB201610198D0 (en) 2016-06-10 2016-06-10 Anti-ige antibodies
GB1610198.2 2016-06-10
GB1702435.7 2017-02-15
GBGB1702435.7A GB201702435D0 (en) 2016-06-10 2017-02-15 Anti-ige antibodies
PCT/EP2017/063916 WO2017211928A1 (en) 2016-06-10 2017-06-08 ANTI-IgE ANTIBODIES
JP2018564417A JP7164439B2 (ja) 2016-06-10 2017-06-08 抗IgE抗体

Related Parent Applications (1)

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JP2018564417A Division JP7164439B2 (ja) 2016-06-10 2017-06-08 抗IgE抗体

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024174078A Division JP2025011170A (ja) 2016-06-10 2024-10-03 抗IgE抗体

Publications (3)

Publication Number Publication Date
JP2023021974A JP2023021974A (ja) 2023-02-14
JP2023021974A5 true JP2023021974A5 (https=) 2023-09-26
JP7612641B2 JP7612641B2 (ja) 2025-01-14

Family

ID=56894897

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018564417A Active JP7164439B2 (ja) 2016-06-10 2017-06-08 抗IgE抗体
JP2022168571A Active JP7612641B2 (ja) 2016-06-10 2022-10-20 抗IgE抗体
JP2024174078A Pending JP2025011170A (ja) 2016-06-10 2024-10-03 抗IgE抗体

Family Applications Before (1)

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JP2018564417A Active JP7164439B2 (ja) 2016-06-10 2017-06-08 抗IgE抗体

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JP2024174078A Pending JP2025011170A (ja) 2016-06-10 2024-10-03 抗IgE抗体

Country Status (26)

Country Link
US (3) US11214627B2 (https=)
EP (1) EP3468995A1 (https=)
JP (3) JP7164439B2 (https=)
KR (1) KR102456813B1 (https=)
CN (1) CN109379892B (https=)
AR (1) AR108707A1 (https=)
AU (1) AU2017277600B2 (https=)
BR (1) BR112018074838A2 (https=)
CA (1) CA3027120A1 (https=)
CL (2) CL2018003556A1 (https=)
CO (1) CO2018013006A2 (https=)
EA (1) EA201990004A1 (https=)
EC (1) ECSP19001438A (https=)
GB (2) GB201610198D0 (https=)
IL (3) IL263452B2 (https=)
MA (1) MA45231A (https=)
MX (1) MX2018014761A (https=)
PE (1) PE20190212A1 (https=)
PH (1) PH12018502574A1 (https=)
SG (1) SG11201810199WA (https=)
TN (1) TN2018000423A1 (https=)
TW (1) TW201802114A (https=)
UA (1) UA126468C2 (https=)
UY (1) UY37290A (https=)
WO (1) WO2017211928A1 (https=)
ZA (2) ZA201807822B (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201610198D0 (en) * 2016-06-10 2016-07-27 Ucb Biopharma Sprl Anti-ige antibodies
SG11201901557XA (en) * 2016-08-26 2019-03-28 Sanofi Sa Multispecific antibodies facilitating selective light chain pairing
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
EP3774925A1 (en) 2018-04-13 2021-02-17 Institut national de la santé et de la recherche médicale (INSERM) Fc-engineered anti-human ige antibodies and methods of use
MA53903A (fr) * 2018-10-16 2021-08-25 UCB Biopharma SRL Méthode de traitement de la myasthénie grave
GB2589049C (en) * 2019-04-11 2024-02-21 argenx BV Anti-IgE antibodies
KR20220044748A (ko) * 2019-07-11 2022-04-11 우한 이지 바이오파마 씨오., 엘티디. 4가 대칭 이중 특이적 항체
AU2020356620A1 (en) 2019-09-25 2022-04-28 Massachusetts Institute Of Technology Therapeutic neutralization antibodies for the treatment of peanut allergy
KR20220070215A (ko) * 2019-10-01 2022-05-30 엡실로겐 리미티드 하이브리드 항체
TWI841810B (zh) 2020-01-24 2024-05-11 日商西斯美股份有限公司 提升抗體對抗原之親和性的方法及其用途
CN113372450A (zh) * 2020-03-10 2021-09-10 北京万华生物工程有限公司 IgE嵌合性双特异性抗体制备及应用
WO2021225980A1 (en) * 2020-05-04 2021-11-11 Dna-Seq, Inc. Methods and systems for determination of an effective therapeutic regimen and drug discovery
WO2021250546A1 (en) 2020-06-09 2021-12-16 University Of Washington Micrornas as predictors of response to anti-ige therapies in chronic spontaneous urticaria
CN111875706B (zh) * 2020-07-16 2021-03-30 广州康盛生物科技股份有限公司 一种抗人IgE蛋白的单域抗体及其应用
EP4206226A4 (en) * 2020-08-31 2024-10-16 Medytox Inc. Anti-vegf hexameric antibody and composition comprising same
WO2022061236A1 (en) * 2020-09-21 2022-03-24 The Board Of Trustees Of The Leland Stanford Junior University High affinity anti-ige antibodies
CN118119641A (zh) * 2021-10-12 2024-05-31 联合生物制药股份有限公司 Ige调节的疾病的治疗
EP4431528A1 (en) * 2021-10-29 2024-09-18 Longbio Pharma (Suzhou) Co., Ltd. Isolated antigen binding protein and use thereof
CN114028569B (zh) * 2021-12-20 2023-04-28 中国医学科学院基础医学研究所 免疫球蛋白IgE在诊断和/或治疗高血压中的用途
CN114504644B (zh) * 2021-12-24 2024-02-13 北京大学第一医院 抗IgE抗体在用于治疗腺样体肥大中的应用
GB2635291A (en) * 2022-07-01 2025-05-07 Alk Abello As Displacers of IgE-FCERI
CN120271714A (zh) * 2022-12-07 2025-07-08 南开大学 一种针对IgE的抗体或其抗原结合片段以及Fc变体
CN118725128B (zh) * 2023-03-28 2025-09-16 东莞市朋志生物科技有限公司 抗IgE抗体、检测IgE的试剂和试剂盒
KR102933992B1 (ko) 2023-05-10 2026-03-05 대한민국 (식품의약품안전처장) 아나필락시스 예측용 바이오마커
CN116754773B (zh) * 2023-05-15 2024-06-07 江南大学 一种免疫球蛋白e的检测试剂盒
CA3237624A1 (en) * 2023-07-28 2025-04-24 Genentech, Inc. NEW USES FOR OMALIZUMAB
CN119490595B (zh) * 2023-08-15 2025-11-18 东莞市朋志生物科技有限公司 一种抗免疫球蛋白e的抗体及其应用
WO2025122927A1 (en) * 2023-12-06 2025-06-12 Integral Molecular, Inc. Antibodies directed to claudin 18.2, including bispecific formats thereof
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
US12509529B2 (en) 2024-05-17 2025-12-30 Excellergy, Inc. Antibodies and antibody fragments that bind IgE
WO2025240780A1 (en) * 2024-05-17 2025-11-20 Excellergy, Inc. Antibodies and antibody fragments that bind ige
CN119841957B (zh) * 2025-01-13 2025-08-05 上海领检科技有限公司 一种抗人IgE抗体及其用途

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US6492107B1 (en) 1986-11-20 2002-12-10 Stuart Kauffman Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
GB2183661B (en) 1985-03-30 1989-06-28 Marc Ballivet Method for obtaining dna, rna, peptides, polypeptides or proteins by means of a dna recombinant technique
DK336987D0 (da) 1987-07-01 1987-07-01 Novo Industri As Immobiliseringsmetode
US5618920A (en) 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
DE3600905A1 (de) 1986-01-15 1987-07-16 Ant Nachrichtentech Verfahren zum dekodieren von binaersignalen sowie viterbi-dekoder und anwendungen
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
GB8719042D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
GB8720833D0 (en) 1987-09-04 1987-10-14 Celltech Ltd Recombinant dna product
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8907617D0 (en) 1989-04-05 1989-05-17 Celltech Ltd Drug delivery system
CA2016842A1 (en) 1989-05-16 1990-11-16 Richard A. Lerner Method for tapping the immunological repertoire
WO1990014443A1 (en) 1989-05-16 1990-11-29 Huse William D Co-expression of heteromeric receptors
CA2016841C (en) 1989-05-16 1999-09-21 William D. Huse A method for producing polymers having a preselected activity
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
EP0542810A1 (en) 1990-08-02 1993-05-26 B.R. Centre Limited Methods for the production of proteins with a desired function
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
GB9112536D0 (en) 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
CA2113813C (en) 1991-08-14 2005-04-12 Paula M. Jardieu Immunoglobulin variants for specific fc epsilon receptors
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
GB9120467D0 (en) 1991-09-26 1991-11-06 Celltech Ltd Anti-hmfg antibodies and process for their production
EP1291360A1 (en) 1991-12-13 2003-03-12 Xoma Corporation Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
FR2716640B1 (fr) 1994-02-28 1996-05-03 Procedes Machines Speciales Dispositif de centrage et de blocage d'une pièce en vue de son rodage à l'aide d'un rodoir à expansion.
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
CA2226575C (en) 1995-07-27 2011-10-18 Genentech, Inc. Stabile isotonic lyophilized protein formulation
ZA966075B (en) 1995-07-27 1998-01-19 Genentech Inc Protein formulation.
ZA971607B (en) * 1996-03-12 1998-08-25 Univ Johns Hopkins Methods of treatment of allergic diseases
US5714352A (en) 1996-03-20 1998-02-03 Xenotech Incorporated Directed switch-mediated DNA recombination
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
US6172213B1 (en) 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
US5994511A (en) 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
AU2103699A (en) * 1998-01-29 1999-08-16 Tse Wen Chang Treating atopic dermatitis with ige antagonists
GB9812545D0 (en) 1998-06-10 1998-08-05 Celltech Therapeutics Ltd Biological products
WO2000072879A1 (en) * 1999-05-26 2000-12-07 Tanox, Inc. TREATING ALLERGIC DISEASES WITH IMMUNOTHERAPY AND IgE ANTAGONISTS
WO2001090190A2 (en) 2000-05-26 2001-11-29 National Research Council Of Canada Single-domain antigen-binding antibody fragments derived from llama antibodies
US6908963B2 (en) 2001-10-09 2005-06-21 Nektar Therapeutics Al, Corporation Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
GB0129105D0 (en) 2001-12-05 2002-01-23 Celltech R&D Ltd Expression control using variable intergenic sequences
US7993864B2 (en) 2002-12-03 2011-08-09 Ucb Pharma S.A. Assay for identifying antibody producing cells
GB0312481D0 (en) 2003-05-30 2003-07-09 Celltech R&D Ltd Antibodies
ES2551439T5 (es) 2003-07-01 2018-11-08 Ucb Biopharma Sprl Fragmentos Fab de anticuerpos modificados
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
GB0411186D0 (en) 2004-05-19 2004-06-23 Celltech R&D Ltd Biological products
GB0412181D0 (en) 2004-06-01 2004-06-30 Celltech R&D Ltd Biological products
GB0502358D0 (en) 2005-02-04 2005-03-16 Novartis Ag Organic compounds
KR20130108481A (ko) 2005-08-19 2013-10-02 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
GB0619291D0 (en) 2006-09-29 2006-11-08 Ucb Sa Altered antibodies
UY30994A1 (es) * 2007-04-02 2008-11-28 Amgen Fremont Inc Anticuerpos anti-ige
CN101801407B (zh) * 2007-06-05 2013-12-18 耶鲁大学 受体酪氨酸激酶抑制剂及其使用方法
WO2009040562A1 (en) 2007-09-26 2009-04-02 Ucb Pharma S.A. Dual specificity antibody fusions
BRPI0822099A2 (pt) 2007-12-21 2017-05-23 Medimmune Ltd membro de ligação isolado, uso de um membro de ligação isolado, método parav tratar um distúrbio, molécula de ácido nucléico isolada, célula hospedeira, e, método para produzir um membro de ligação
JP5470817B2 (ja) 2008-03-10 2014-04-16 日産自動車株式会社 電池用電極およびこれを用いた電池、並びにその製造方法
CN101230103B (zh) * 2008-03-25 2011-09-07 中国医药集团总公司四川抗菌素工业研究所 一全人源重组抗-IgE抗体
HRP20170374T1 (hr) 2008-09-26 2017-05-05 Ucb Biopharma Sprl Biološki proizvodi
US20120283415A1 (en) 2009-09-10 2012-11-08 Ucb Pharma S.A. Multivalent Antibodies
JP6139885B2 (ja) 2009-10-26 2017-05-31 ジェネンテック, インコーポレイテッド 治療的抗IgE抗体に特異的な抗体を検出するためのアッセイ及びアナフィラキシーにおけるそれらの使用
US8735546B2 (en) 2010-08-03 2014-05-27 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
AU2012335496B2 (en) * 2011-11-11 2017-05-11 Ucb Biopharma Sprl Albumin binding antibodies and binding fragments thereof
KR20140119777A (ko) 2012-01-31 2014-10-10 제넨테크, 인크. 항-ig-e m1'' 항체 및 그의 사용 방법
US20150140608A1 (en) 2012-06-01 2015-05-21 Momenta Pharmaceuticals, Inc. Methods related to omalizumab
JP6136279B2 (ja) 2013-01-15 2017-05-31 株式会社ジェイテクト 転がり軸受装置
TWI503850B (zh) 2013-03-22 2015-10-11 Polytronics Technology Corp 過電流保護元件
WO2015013668A1 (en) 2013-07-26 2015-01-29 Ke Zhang Anti-immunoglobulin e antibodies and methods of use thereof
TWI510996B (zh) 2013-10-03 2015-12-01 Acer Inc 控制觸控面板的方法以及使用該方法的可攜式電腦
CN104987412A (zh) 2015-07-14 2015-10-21 上海拜豪生物科技有限公司 一种砷-IgE螯合物及其制备方法和应用
US20180273626A1 (en) 2015-09-11 2018-09-27 The Board Of Trustees Of The Leland Stanford Junio University Omalizumab resistant ige variants and their use in anti-ige therapy
GB201610198D0 (en) * 2016-06-10 2016-07-27 Ucb Biopharma Sprl Anti-ige antibodies
US9816280B1 (en) 2016-11-02 2017-11-14 Matthew Reitnauer Portable floor

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