JP2023134618A5 - - Google Patents

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Publication number
JP2023134618A5
JP2023134618A5 JP2023114162A JP2023114162A JP2023134618A5 JP 2023134618 A5 JP2023134618 A5 JP 2023134618A5 JP 2023114162 A JP2023114162 A JP 2023114162A JP 2023114162 A JP2023114162 A JP 2023114162A JP 2023134618 A5 JP2023134618 A5 JP 2023134618A5
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JP
Japan
Prior art keywords
antibody
cdr
region
antigen
amino acid
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JP2023114162A
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English (en)
Japanese (ja)
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JP2023134618A (ja
JP7605916B2 (ja
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Priority claimed from EP17169953.1A external-priority patent/EP3401332A1/en
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Publication of JP2023134618A publication Critical patent/JP2023134618A/ja
Publication of JP2023134618A5 publication Critical patent/JP2023134618A5/ja
Priority to JP2024216380A priority Critical patent/JP7825695B2/ja
Application granted granted Critical
Publication of JP7605916B2 publication Critical patent/JP7605916B2/ja
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JP2023114162A 2017-05-08 2023-07-12 炎症症状で使用するための抗ｉｌ－１ｒ３抗体 Active JP7605916B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024216380A JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP17169953.1A EP3401332A1 (en) 2017-05-08 2017-05-08 Anti-il-1r3 antibodies for use in inflammatory conditions
EP17169953.1 2017-05-08
PCT/EP2018/061846 WO2018206565A1 (en) 2017-05-08 2018-05-08 Anti-il-1r3 antibodies for use in inflammatory conditions
JP2019561281A JP7315472B2 (ja) 2017-05-08 2018-05-08 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Related Parent Applications (1)

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JP2019561281A Division JP7315472B2 (ja) 2017-05-08 2018-05-08 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Related Child Applications (1)

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JP2024216380A Division JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Publications (3)

Publication Number Publication Date
JP2023134618A JP2023134618A (ja) 2023-09-27
JP2023134618A5 true JP2023134618A5 (https=) 2024-04-03
JP7605916B2 JP7605916B2 (ja) 2024-12-24

Family

ID=58698976

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019561281A Active JP7315472B2 (ja) 2017-05-08 2018-05-08 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP2023114162A Active JP7605916B2 (ja) 2017-05-08 2023-07-12 炎症症状で使用するための抗ｉｌ－１ｒ３抗体
JP2024216380A Active JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Family Applications Before (1)

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JP2019561281A Active JP7315472B2 (ja) 2017-05-08 2018-05-08 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024216380A Active JP7825695B2 (ja) 2017-05-08 2024-12-11 炎症症状で使用するための抗ｉｌ－１ｒ３抗体

Country Status (7)

Country Link
US (2) US11639392B2 (https=)
EP (2) EP3401332A1 (https=)
JP (3) JP7315472B2 (https=)
CN (1) CN110831670A (https=)
AU (2) AU2018267092B2 (https=)
CA (1) CA3062424A1 (https=)
WO (1) WO2018206565A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7114460B2 (ja) 2015-06-26 2022-08-08 サノフィ・バイオテクノロジー モノクローナル抗ＩＬ－１ＲＡｃＰ抗体
EP3241845A1 (en) 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
CA3055256A1 (en) * 2017-03-09 2018-09-13 Mab Discovery Gmbh Antibodies specifically binding to human il-1r7
EP3401332A1 (en) * 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions
CA3066918A1 (en) 2017-06-12 2018-12-20 Bluefin Biomedicine, Inc. Anti-il1rap antibodies and antibody drug conjugates
LT3684813T (lt) * 2017-09-19 2026-01-26 Mab Discovery Gmbh Agonistiniai cd40 antikūnai
TW202021618A (zh) * 2018-08-17 2020-06-16 美商２３與我有限公司 抗ｉｌ１ｒａｐ抗體及其使用方法
CA3120474A1 (en) * 2018-12-21 2020-06-25 23Andme, Inc. Anti-il-36 antibodies and methods of use thereof
WO2020232148A1 (en) * 2019-05-13 2020-11-19 The Johns Hopkins University Macrophage diversity in regenerative, fibrotic biomaterial environments
CA3220913A1 (en) 2021-05-21 2022-11-24 Leo Pharma A/S Anti il-1 receptor accessory protein antibodies
AR130550A1 (es) * 2022-09-21 2024-12-18 Sanofi Biotechnology Anticuerpo anti-il-1r3 humanizado y métodos de uso
US20260015427A1 (en) 2024-06-25 2026-01-15 Kiniksa Pharmaceuticals, Gmbh Formulations of anti-interleukin 1 receptor 1 antibodies
WO2026022232A1 (en) 2024-07-24 2026-01-29 Almirall, S.A. Il-1rap inhibitor for treating or preventing hidradenitis suppurativa

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204244A (en) 1987-10-27 1993-04-20 Oncogen Production of chimeric antibodies by homologous recombination
US5202238A (en) 1987-10-27 1993-04-13 Oncogen Production of chimeric antibodies by homologous recombination
US5283179A (en) 1990-09-10 1994-02-01 Promega Corporation Luciferase assay method
DK0488470T3 (da) 1990-11-26 1997-12-22 Akzo Nobel Nv Fremgangsmåde til fremstilling af antistoffer
PE64396A1 (es) 1995-01-23 1997-01-28 Hoffmann La Roche Proteina accesoria del receptor de la interleucina 1
US6974682B1 (en) 1996-08-26 2005-12-13 Human Genome Sciences, Inc. Soluble interleukin-1 receptor accessory molecule
WO1998048032A2 (en) 1997-04-21 1998-10-29 Donlar Corporation POLY-(α-L-ASPARTIC ACID), POLY-(α-L-GLUTAMIC ACID) AND COPOLYMERS OF L-ASP AND L-GLU, METHOD FOR THEIR PRODUCTION AND THEIR USE
US6280955B1 (en) 1997-12-16 2001-08-28 Tularik Inc. Interleukin-1 receptor accessory proteins, nucleic acids and methods
DK1071700T3 (da) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
US6541225B1 (en) 2000-01-26 2003-04-01 Raven Biotechnologies, Inc. Methods and compositions for generating human monoclonal antibodies
US7449443B2 (en) 2000-03-23 2008-11-11 California Institute Of Technology Method for stabilization of proteins using non-natural amino acids
US6586207B2 (en) 2000-05-26 2003-07-01 California Institute Of Technology Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues
US20030026806A1 (en) 2000-10-27 2003-02-06 Amgen Inc. Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof
WO2002064630A2 (en) 2000-10-31 2002-08-22 Immunex Corporation Il-1 receptor accessory protein
US20030049255A1 (en) 2001-08-07 2003-03-13 Sims John E. Interleukin-1 receptors in the treatment of diseases
WO2003073238A2 (en) 2002-02-27 2003-09-04 California Institute Of Technology Computational method for designing enzymes for incorporation of amino acid analogs into proteins
KR101317045B1 (ko) 2002-09-06 2013-10-16 암젠 인코포레이티드 치료학적 인체 항-ｉｌ-1ｒ1 모노클로날 항체
EP2248892B1 (en) 2003-01-22 2015-04-22 Roche Glycart AG Fusion constructs and use of same to produce antibodies with increased FC receptor binding affinity and effector function
US20040224893A1 (en) 2003-05-06 2004-11-11 Li-Hsien Wang Methods of using IL-1 antagonists to treat neointimal hyperplasia
GB0312481D0 (en) 2003-05-30 2003-07-09 Celltech R&D Ltd Antibodies
WO2005035727A2 (en) 2003-10-09 2005-04-21 Ambrx, Inc. Polymer derivatives
US9296820B2 (en) 2003-11-05 2016-03-29 Roche Glycart Ag Polynucleotides encoding anti-CD20 antigen binding molecules with increased Fc receptor binding affinity and effector function
US20090215895A1 (en) 2004-01-30 2009-08-27 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
BRPI0507169A (pt) 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
EP1910513B1 (en) 2005-07-01 2016-08-10 John Schrader Methods of isolating antibody secreting cells from blood samples of immunized animals and generating monoclonal antibodies from said antibody secreting cells.
AU2006290433B2 (en) 2005-08-26 2012-06-07 Roche Glycart Ag Modified antigen binding molecules with altered cell signaling activity
EP2021463B1 (en) 2006-05-19 2016-11-23 Alder Biopharmaceuticals, Inc. Culture method for obtaining a clonal population of antigen-specific b cells
WO2009120905A2 (en) 2008-03-26 2009-10-01 Cellerant Therapeutics, Inc. Immunoglobulin and/or toll-like receptor proteins associated with myelogenous haematological proliferative disorders and uses thereof
MY152068A (en) 2009-03-20 2014-08-15 Genentech Inc Bispecific anti-her antibodies
GB2472856B (en) 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof
EP2556087A1 (en) 2010-04-09 2013-02-13 Novozymes Biopharma DK A/S Albumin derivatives and variants
SI2400298T1 (sl) 2010-05-28 2013-11-29 F. Hoffmann-La Roche Ag Postopek kultivacije posamezne B-celice in izdelava specifičnih protiteles
US9403906B2 (en) 2011-01-19 2016-08-02 Cantargia Ab Method of treatment of a solid tumor with interleukin-1 accessory protein antibody
ES2692268T5 (en) 2011-03-29 2025-02-26 Roche Glycart Ag Antibody fc variants
EP2697260A1 (en) * 2011-04-15 2014-02-19 Merck Patent GmbH Anti- il-1r1 inhibitors for use in cancer
CA2837651A1 (en) 2011-06-21 2012-12-27 Oncofactor Corporation Compositions and methods for the therapy and diagnosis of cancer
US9873918B2 (en) 2011-08-11 2018-01-23 Albert Einstein College Of Medicine, Inc. Treatment of acute myeloid leukemia and myelodysplastic syndromes
US9090694B2 (en) 2012-04-30 2015-07-28 Janssen Biotech, Inc. ST2L antibody antagonists
WO2014100772A1 (en) 2012-12-21 2014-06-26 Cellerant Therapeutics, Inc. Antibodies that bind membrane-bound il1rap
WO2014113433A1 (en) 2013-01-16 2014-07-24 George Mason University Binding domain mapping
GB201403875D0 (en) 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
GB201413913D0 (en) * 2014-08-06 2014-09-17 Cantargia Ab Novel antibodies and uses thereof
JP7114460B2 (ja) 2015-06-26 2022-08-08 サノフィ・バイオテクノロジー モノクローナル抗ＩＬ－１ＲＡｃＰ抗体
EP3241845A1 (en) 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
EP3401332A1 (en) 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions

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