JP2022553908A5 - - Google Patents
Info
- Publication number
- JP2022553908A5 JP2022553908A5 JP2022521074A JP2022521074A JP2022553908A5 JP 2022553908 A5 JP2022553908 A5 JP 2022553908A5 JP 2022521074 A JP2022521074 A JP 2022521074A JP 2022521074 A JP2022521074 A JP 2022521074A JP 2022553908 A5 JP2022553908 A5 JP 2022553908A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- sequence includes
- region amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025087525A JP2025134713A (ja) | 2019-10-11 | 2025-05-26 | Ｐｄ１およびｖｅｇｆｒ２二重結合剤 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1914747.9 | 2019-10-11 | ||
| GB201914747A GB201914747D0 (en) | 2019-10-11 | 2019-10-11 | PD1 and vegfr2 dual-binding agents |
| GBGB2013180.1A GB202013180D0 (en) | 2019-10-11 | 2020-08-24 | Pd1 and vegfr2 dual-binding agents |
| GB2013180.1 | 2020-08-24 | ||
| PCT/EP2020/078427 WO2021069670A1 (en) | 2019-10-11 | 2020-10-09 | Pd1 and vegfr2 dual-binding agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025087525A Division JP2025134713A (ja) | 2019-10-11 | 2025-05-26 | Ｐｄ１およびｖｅｇｆｒ２二重結合剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022553908A JP2022553908A (ja) | 2022-12-27 |
| JP2022553908A5 true JP2022553908A5 (https=) | 2023-10-17 |
| JP7689116B2 JP7689116B2 (ja) | 2025-06-05 |
Family
ID=68619556
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022521074A Active JP7689116B2 (ja) | 2019-10-11 | 2020-10-09 | Ｐｄ１およびｖｅｇｆｒ２二重結合剤 |
| JP2025087525A Pending JP2025134713A (ja) | 2019-10-11 | 2025-05-26 | Ｐｄ１およびｖｅｇｆｒ２二重結合剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025087525A Pending JP2025134713A (ja) | 2019-10-11 | 2025-05-26 | Ｐｄ１およびｖｅｇｆｒ２二重結合剤 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20240101674A1 (https=) |
| EP (3) | EP4041763B1 (https=) |
| JP (2) | JP7689116B2 (https=) |
| KR (1) | KR20220091490A (https=) |
| CN (2) | CN114981301B (https=) |
| AU (1) | AU2020365021A1 (https=) |
| CA (2) | CA3289307A1 (https=) |
| DK (1) | DK4041763T3 (https=) |
| ES (1) | ES3027238T3 (https=) |
| FI (1) | FI4041763T3 (https=) |
| GB (2) | GB201914747D0 (https=) |
| HR (1) | HRP20250523T1 (https=) |
| HU (1) | HUE071341T2 (https=) |
| IL (1) | IL292158A (https=) |
| LT (1) | LT4041763T (https=) |
| PL (1) | PL4041763T3 (https=) |
| PT (1) | PT4041763T (https=) |
| RS (1) | RS66837B1 (https=) |
| SI (1) | SI4041763T1 (https=) |
| WO (1) | WO2021069670A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109053895B (zh) | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| GB201914747D0 (en) | 2019-10-11 | 2019-11-27 | Ultrahuman Eight Ltd | PD1 and vegfr2 dual-binding agents |
| CN116143935A (zh) * | 2021-11-22 | 2023-05-23 | 杭州翰思生物医药有限公司 | 重组抗体及其应用 |
| WO2024032662A1 (zh) * | 2022-08-09 | 2024-02-15 | 上海济煜医药科技有限公司 | 一种靶向pd-1和vegf的抗体及其应用 |
| CN118620082A (zh) * | 2023-03-10 | 2024-09-10 | 南京维立志博生物科技有限公司 | 靶向vegf途径和pd-1的双特异性抗原结合蛋白、其组合物和用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2439273T3 (da) | 2005-05-09 | 2019-06-03 | Ono Pharmaceutical Co | Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika |
| BR122017025062B8 (pt) | 2007-06-18 | 2021-07-27 | Merck Sharp & Dohme | anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento |
| RU2689760C2 (ru) * | 2012-05-31 | 2019-05-30 | Дженентек, Инк. | Способы лечения рака с применением антагонистов аксиального связывания pd-1 и vegf антагонистов |
| CN112552401B (zh) | 2013-09-13 | 2023-08-25 | 广州百济神州生物制药有限公司 | 抗pd1抗体及其作为治疗剂与诊断剂的用途 |
| SG10201804945WA (en) * | 2013-12-12 | 2018-07-30 | Shanghai hengrui pharmaceutical co ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| WO2017055404A1 (en) | 2015-10-02 | 2017-04-06 | F. Hoffmann-La Roche Ag | Bispecific antibodies specific for pd1 and tim3 |
| CN109893654B (zh) * | 2017-12-11 | 2021-07-27 | 江苏恒瑞医药股份有限公司 | Vegfr抑制剂治疗肿瘤的方法 |
| GB201803746D0 (en) | 2018-03-08 | 2018-04-25 | Ultrahuman Eight Ltd | PD1 binding agents |
| GB201803745D0 (en) | 2018-03-08 | 2018-04-25 | Ultrahuman Eight Ltd | PD1 binding agents |
| CN109053895B (zh) * | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| TWI822897B (zh) | 2018-11-06 | 2023-11-21 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種抗pd-1抗體和法米替尼聯合在製備治療腫瘤的藥物中的用途 |
| GB201914747D0 (en) | 2019-10-11 | 2019-11-27 | Ultrahuman Eight Ltd | PD1 and vegfr2 dual-binding agents |
-
2019
- 2019-10-11 GB GB201914747A patent/GB201914747D0/en not_active Ceased
-
2020
- 2020-08-24 GB GBGB2013180.1A patent/GB202013180D0/en not_active Ceased
- 2020-10-09 LT LTEPPCT/EP2020/078427T patent/LT4041763T/lt unknown
- 2020-10-09 DK DK20789105.2T patent/DK4041763T3/da active
- 2020-10-09 SI SI202030611T patent/SI4041763T1/sl unknown
- 2020-10-09 HR HRP20250523TT patent/HRP20250523T1/hr unknown
- 2020-10-09 CN CN202080075802.2A patent/CN114981301B/zh active Active
- 2020-10-09 CN CN202511932691.3A patent/CN121758618A/zh active Pending
- 2020-10-09 AU AU2020365021A patent/AU2020365021A1/en active Pending
- 2020-10-09 US US17/768,013 patent/US20240101674A1/en active Pending
- 2020-10-09 CA CA3289307A patent/CA3289307A1/en active Pending
- 2020-10-09 PL PL20789105.2T patent/PL4041763T3/pl unknown
- 2020-10-09 HU HUE20789105A patent/HUE071341T2/hu unknown
- 2020-10-09 EP EP20789105.2A patent/EP4041763B1/en active Active
- 2020-10-09 WO PCT/EP2020/078427 patent/WO2021069670A1/en not_active Ceased
- 2020-10-09 JP JP2022521074A patent/JP7689116B2/ja active Active
- 2020-10-09 EP EP25159487.5A patent/EP4570824A3/en active Pending
- 2020-10-09 ES ES20789105T patent/ES3027238T3/es active Active
- 2020-10-09 KR KR1020227014433A patent/KR20220091490A/ko active Pending
- 2020-10-09 PT PT207891052T patent/PT4041763T/pt unknown
- 2020-10-09 CA CA3156096A patent/CA3156096C/en active Active
- 2020-10-09 FI FIEP20789105.2T patent/FI4041763T3/fi active
- 2020-10-09 RS RS20250448A patent/RS66837B1/sr unknown
- 2020-10-09 EP EP25212556.2A patent/EP4671279A2/en active Pending
-
2022
- 2022-04-11 IL IL292158A patent/IL292158A/en unknown
-
2025
- 2025-02-18 US US19/056,312 patent/US12479920B2/en active Active
- 2025-05-26 JP JP2025087525A patent/JP2025134713A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021519100A5 (https=) | ||
| JP2021515541A5 (https=) | ||
| JP2022553908A5 (https=) | ||
| JP2021515542A5 (https=) | ||
| JP2021513323A5 (https=) | ||
| JP2022177090A5 (https=) | ||
| HRP20200583T1 (hr) | Protutijela koja neutraliziraju gp120 i njihova upotreba | |
| TW202126692A (zh) | 抗人Claudin18.2抗體及其應用 | |
| HRP20250523T1 (hr) | Pd1 i vegfr2 sredstva za dvostruko vezivanje | |
| JP2024513921A5 (https=) | ||
| JP2021521843A5 (https=) | ||
| JP2020531048A5 (https=) | ||
| JP2018506961A5 (https=) | ||
| JP2020514277A5 (https=) | ||
| JP2019500892A5 (https=) | ||
| JP2019500891A5 (https=) | ||
| JP7679399B2 (ja) | 抗ｆｌｔ３抗体及び組成物 | |
| RU2019121086A (ru) | Иммунотерапия с применением антител, связывающих лиганд 1 белка программируемой смерти клеток (PD-L1) | |
| JP2021516537A5 (https=) | ||
| US20250034273A1 (en) | Composition of multispecific antibodies targeting cadherin-17-expressing tumors and method of making and using thereof | |
| JP2024540148A5 (https=) | ||
| JP2020521504A (ja) | 抗ｃｄ４０抗体、その抗原結合フラグメント、およびその医学的使用 | |
| JP2021534797A5 (https=) | ||
| JP2023522730A5 (https=) | ||
| JP2023542209A5 (https=) |