JP2023542209A5 - - Google Patents

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Publication number
JP2023542209A5
JP2023542209A5 JP2023518383A JP2023518383A JP2023542209A5 JP 2023542209 A5 JP2023542209 A5 JP 2023542209A5 JP 2023518383 A JP2023518383 A JP 2023518383A JP 2023518383 A JP2023518383 A JP 2023518383A JP 2023542209 A5 JP2023542209 A5 JP 2023542209A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
antibody
antibody fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2023518383A
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English (en)
Japanese (ja)
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JP7851303B2 (ja
JP2023542209A (ja
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Priority claimed from PCT/EP2021/076052 external-priority patent/WO2022063819A1/en
Publication of JP2023542209A publication Critical patent/JP2023542209A/ja
Publication of JP2023542209A5 publication Critical patent/JP2023542209A5/ja
Application granted granted Critical
Publication of JP7851303B2 publication Critical patent/JP7851303B2/ja
Active legal-status Critical Current
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JP2023518383A 2020-09-24 2021-09-22 ヒトcd3イプシロンに結合する新規なヒト抗体 Active JP7851303B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20197975.4 2020-09-24
EP20197975 2020-09-24
PCT/EP2021/076052 WO2022063819A1 (en) 2020-09-24 2021-09-22 Novel human antibodies binding to human cd3 epsilon

Publications (3)

Publication Number Publication Date
JP2023542209A JP2023542209A (ja) 2023-10-05
JP2023542209A5 true JP2023542209A5 (https=) 2024-09-24
JP7851303B2 JP7851303B2 (ja) 2026-04-24

Family

ID=72644112

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023518383A Active JP7851303B2 (ja) 2020-09-24 2021-09-22 ヒトcd3イプシロンに結合する新規なヒト抗体

Country Status (9)

Country Link
US (1) US20230357398A1 (https=)
EP (1) EP4217391A1 (https=)
JP (1) JP7851303B2 (https=)
KR (1) KR20230074192A (https=)
CN (1) CN116209680A (https=)
AU (1) AU2021350342A1 (https=)
CA (1) CA3189473A1 (https=)
IL (1) IL301276A (https=)
WO (1) WO2022063819A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3227537A1 (en) 2021-07-27 2023-02-02 Morphosys Ag Combinations of antigen binding molecules
JP2026502768A (ja) * 2022-10-25 2026-01-27 アブレクシス, エルエルシー 抗cd3抗体
WO2025003511A1 (en) 2023-06-30 2025-01-02 Morphosys Ag Dual-targeting of flt3 and cd123 co-expressing tumor cells by functional complementation of cycat® halfbody molecules
WO2025036892A1 (en) 2023-08-14 2025-02-20 Morphosys Ag Cycat halfbody molecules comprising sterically occluding moieties
WO2025082777A1 (en) 2023-10-17 2025-04-24 Morphosys Ag Dual-targeting of muc16 and mesothelin co-expressing tumor cells by functional complementation of cycat® halfbody molecules

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
EP1958962A3 (en) 1997-06-12 2013-05-01 Novartis International Pharmaceutical Ltd. Artificial antibody polypeptides
US6136599A (en) 1998-12-10 2000-10-24 Bayer Corporation Human hybrid host cell for mammalian gene expression
ES2327382T3 (es) 1999-07-20 2009-10-29 Morphosys Ag Metodos para presentar (poli)peptidos/proteinas en particulas de bacteriofagos a traves de enlaces disulfuro.
RS53008B2 (sr) 2007-04-03 2022-12-30 Amgen Res Munich Gmbh Interspecijski specifičan cd3-epsilon vezujući domen
US8367586B2 (en) 2010-11-19 2013-02-05 Morphosys Ag Collection and methods for its use
CA2861003C (en) 2012-01-13 2023-03-28 Julius-Maximilians-Universitat Wurzburg Dual antigen-induced bipartite functional complementation
CN106459201A (zh) * 2014-05-28 2017-02-22 豪夫迈·罗氏有限公司 结合人和食蟹猴CD3ε的抗体
WO2019034580A1 (en) 2017-08-14 2019-02-21 Morphosys Ag HUMANIZED ANTIBODIES FOR CD3
WO2020115115A1 (en) 2018-12-05 2020-06-11 Morphosys Ag Multispecific antigen-binding molecules

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