JP2022553375A5 - - Google Patents

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Publication number
JP2022553375A5
JP2022553375A5 JP2022523854A JP2022523854A JP2022553375A5 JP 2022553375 A5 JP2022553375 A5 JP 2022553375A5 JP 2022523854 A JP2022523854 A JP 2022523854A JP 2022523854 A JP2022523854 A JP 2022523854A JP 2022553375 A5 JP2022553375 A5 JP 2022553375A5
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JP
Japan
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JP2022523854A
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Japanese (ja)
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JP2022553375A (ja
JP7826197B2 (ja
JPWO2021081225A5 (https=
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Priority claimed from PCT/US2020/056890 external-priority patent/WO2021081225A1/en
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Publication of JPWO2021081225A5 publication Critical patent/JPWO2021081225A5/ja
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JP2022523854A 2019-10-22 2020-10-22 オルニチントランスカルバミラーゼ(otc)構築物およびそれを使用する方法 Active JP7826197B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962924567P 2019-10-22 2019-10-22
US62/924,567 2019-10-22
PCT/US2020/056890 WO2021081225A1 (en) 2019-10-22 2020-10-22 Ornithine transcarbamylase (otc) constructs and methods of using the same

Publications (4)

Publication Number Publication Date
JP2022553375A JP2022553375A (ja) 2022-12-22
JP2022553375A5 true JP2022553375A5 (https=) 2023-10-26
JPWO2021081225A5 JPWO2021081225A5 (https=) 2023-10-26
JP7826197B2 JP7826197B2 (ja) 2026-03-09

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JP2022523854A Active JP7826197B2 (ja) 2019-10-22 2020-10-22 オルニチントランスカルバミラーゼ(otc)構築物およびそれを使用する方法

Country Status (9)

Country Link
US (1) US20230001021A1 (https=)
EP (1) EP4048317A4 (https=)
JP (1) JP7826197B2 (https=)
KR (1) KR20240130161A (https=)
CN (1) CN116096428A (https=)
AU (1) AU2020371697A1 (https=)
CA (1) CA3158626A1 (https=)
IL (1) IL292420A (https=)
WO (1) WO2021081225A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113166783B (zh) 2018-10-09 2024-10-11 不列颠哥伦比亚大学 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法
WO2022229903A1 (en) * 2021-04-28 2022-11-03 Genevant Sciences Gmbh Mrna delivery constructs and methods of using the same
KR20230083893A (ko) * 2021-12-03 2023-06-12 고려대학교 산학협력단 번역 효율이 향상된 5'-utr, 이를 포함하는 합성 핵산 분자 및 이를 포함하는 백신 또는 치료제 조성물
KR20250169641A (ko) * 2023-03-06 2025-12-03 제네럴 메디신스 엘엘씨 코돈 최적화 및 이의 사용 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201405157PA (en) 2012-02-24 2014-10-30 Protiva Biotherapeutics Inc Trialkyl cationic lipids and methods of use thereof
WO2015011633A1 (en) * 2013-07-23 2015-01-29 Protiva Biotherapeutics, Inc. Compositions and methods for delivering messenger rna
EP3027221A1 (en) * 2013-07-30 2016-06-08 PhaseRx, Inc. Block copolymers and their conjugates or complexes with oligonucleotides
US9765477B2 (en) * 2013-08-23 2017-09-19 Dow Global Technologies Llc Low density attached polyurethane foams made using a combination of frothing and blowing methods
US11219634B2 (en) * 2015-01-21 2022-01-11 Genevant Sciences Gmbh Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells
CA3027312A1 (en) * 2016-06-13 2017-12-21 Translate Bio, Inc. Messenger rna therapy for the treatment of ornithine transcarbamylase deficiency
FI3568483T3 (fi) * 2017-01-10 2025-11-21 Childrens Medical Res Institute Polynukleotideja ja vektoreita siirtogeenien ilmentämiseen
EP3714048B1 (en) * 2017-11-22 2025-04-09 ModernaTX, Inc. Polynucleotides encoding ornithine transcarbamylase for the treatment of urea cycle disorders

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