JP2025510946A5 - - Google Patents

Info

Publication number
JP2025510946A5
JP2025510946A5 JP2024557464A JP2024557464A JP2025510946A5 JP 2025510946 A5 JP2025510946 A5 JP 2025510946A5 JP 2024557464 A JP2024557464 A JP 2024557464A JP 2024557464 A JP2024557464 A JP 2024557464A JP 2025510946 A5 JP2025510946 A5 JP 2025510946A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
aav
acid sequence
capsid polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024557464A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025510946A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/016860 external-priority patent/WO2023192454A2/en
Publication of JP2025510946A publication Critical patent/JP2025510946A/ja
Publication of JP2025510946A5 publication Critical patent/JP2025510946A5/ja
Pending legal-status Critical Current

Links

JP2024557464A 2022-03-30 2023-03-30 網膜領域にまたがり核酸を送達するためのアデノ随伴ウイルスベクター Pending JP2025510946A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202263325544P 2022-03-30 2022-03-30
US202263325562P 2022-03-30 2022-03-30
US202263325558P 2022-03-30 2022-03-30
US202263325542P 2022-03-30 2022-03-30
US202263325543P 2022-03-30 2022-03-30
US202263325553P 2022-03-30 2022-03-30
US63/325,543 2022-03-30
US63/325,544 2022-03-30
US63/325,553 2022-03-30
US63/325,562 2022-03-30
US63/325,542 2022-03-30
US63/325,558 2022-03-30
PCT/US2023/016860 WO2023192454A2 (en) 2022-03-30 2023-03-30 Adeno-associated virus vectors for nucleic acid delivery across retinal regions

Publications (2)

Publication Number Publication Date
JP2025510946A JP2025510946A (ja) 2025-04-15
JP2025510946A5 true JP2025510946A5 (https=) 2026-04-07

Family

ID=88203537

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024557464A Pending JP2025510946A (ja) 2022-03-30 2023-03-30 網膜領域にまたがり核酸を送達するためのアデノ随伴ウイルスベクター

Country Status (11)

Country Link
US (1) US20250222135A1 (https=)
EP (1) EP4499847A4 (https=)
JP (1) JP2025510946A (https=)
KR (1) KR20240168434A (https=)
CN (1) CN119213134A (https=)
AU (1) AU2023245716A1 (https=)
CA (1) CA3255242A1 (https=)
IL (1) IL315751A (https=)
MX (1) MX2024011862A (https=)
TW (1) TW202405181A (https=)
WO (1) WO2023192454A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025231339A1 (en) * 2024-05-02 2025-11-06 Avista Therapeutics, Inc. Adeno-associated virus vectors for therapeutic nucleic acid delivery to retinal cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156303A (en) * 1997-06-11 2000-12-05 University Of Washington Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
US7504490B1 (en) * 1998-10-16 2009-03-17 Oscient Pharmaceuticals Corporation Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics
US20040031072A1 (en) * 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
CN105755044A (zh) * 2011-04-22 2016-07-13 加利福尼亚大学董事会 具有变异衣壳的腺相关病毒病毒体及其使用方法
AU2017341849B2 (en) * 2016-10-13 2024-03-21 University Of Massachusetts AAV capsid designs
CA3053154A1 (en) * 2017-06-30 2019-01-03 The Regents Of The University Of California Adeno-associated virus virions with variant capsids and methods of use thereof
US20230265455A1 (en) * 2020-07-29 2023-08-24 University Of Florida Research Foundation, Incorporated Improved aav-mediated x-linked retinoschisis therapies

Similar Documents

Publication Publication Date Title
JP7854334B2 (ja) ファージミドベクター
JP2021520203A (ja) 減少した肝臓向性を有するAAV9とAAVrh74とのハイブリッド組換えアデノ随伴ウイルス血清型
US20180030096A1 (en) Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof
US20020192823A1 (en) AAV2 vectors and methods
JP2022516317A5 (https=)
JP2022520232A5 (https=)
JP2019524090A5 (https=)
JP2025537601A (ja) 組換えアデノ随伴ウイルスベクターの薬学的組成物及びその適用
WO2021042944A1 (zh) 肌肉靶向的微环dna基因治疗
CN114276419B (zh) 肌肉高亲和性的新型腺相关病毒衣壳蛋白及其应用
JP2020533968A5 (https=)
JP2023040219A5 (https=)
IL298772A (en) Coding-optimized nucleic acid encoding the SMN1 protein and its use
WO2023108157A1 (en) Methods and compositions for treating mybpc3 related hypertrophic cardiomyopathy with a viral vector
JP2025510946A5 (https=)
JP2025510975A5 (https=)
WO2022222869A1 (zh) 重组腺相关病毒及其应用
WO2023192450A1 (en) Adeno-associated virus vectors for nucleic acid delivery to retinal ganglion cells and/or retinal pigment epithelium cells
WO2023108130A2 (en) Compositions comprising kozak sequences selected for enhanced expression
JP2024528997A (ja) 放射線誘発性唾液機能低下を予防するためのaqp1遺伝子療法
CA3255255A1 (en) Adeno-associated viral vectors for the delivery of nucleic acids to retinal cells
JP2025512534A5 (https=)
RU2024132390A (ru) Векторы на основе аденоассоциированного вируса для доставки нуклеиновых кислот в области сетчатки
RU2024132391A (ru) Векторы на основе аденоассоциированного вируса для доставки нуклеиновых кислот в клетки сетчатки
CN121759520A (zh) 一种lamp2b的过表达载体及其应用