JP2022549863A5 - - Google Patents

Info

Publication number
JP2022549863A5
JP2022549863A5 JP2022519042A JP2022519042A JP2022549863A5 JP 2022549863 A5 JP2022549863 A5 JP 2022549863A5 JP 2022519042 A JP2022519042 A JP 2022519042A JP 2022519042 A JP2022519042 A JP 2022519042A JP 2022549863 A5 JP2022549863 A5 JP 2022549863A5
Authority
JP
Japan
Prior art keywords
formula
compound
chlorobenzyl
methylmorpholino
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022519042A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022549863A (ja
JP7697933B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2020/058984 external-priority patent/WO2021059220A1/en
Publication of JP2022549863A publication Critical patent/JP2022549863A/ja
Publication of JP2022549863A5 publication Critical patent/JP2022549863A5/ja
Application granted granted Critical
Publication of JP7697933B2 publication Critical patent/JP7697933B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022519042A 2019-09-25 2020-09-25 ５－（４－（（２ｓ，５ｓ）－５－（４－クロロベンジル）－２－メチルモルホリノ）ピペリジン－１－イル）－１ｈ－１，２，４－トリアゾール－３－アミンの製造プロセス Active JP7697933B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962905494P 2019-09-25 2019-09-25
PL43126919 2019-09-25
PLP.431269 2019-09-25
US62/905,494 2019-09-25
PCT/IB2020/058984 WO2021059220A1 (en) 2019-09-25 2020-09-25 Process for the production of 5-(4-((2 s,5 s)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1 h-1,2,4-triazol-3-amine

Publications (3)

Publication Number Publication Date
JP2022549863A JP2022549863A (ja) 2022-11-29
JP2022549863A5 true JP2022549863A5 (https=) 2023-06-08
JP7697933B2 JP7697933B2 (ja) 2025-06-24

Family

ID=73139065

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022519042A Active JP7697933B2 (ja) 2019-09-25 2020-09-25 ５－（４－（（２ｓ，５ｓ）－５－（４－クロロベンジル）－２－メチルモルホリノ）ピペリジン－１－イル）－１ｈ－１，２，４－トリアゾール－３－アミンの製造プロセス

Country Status (16)

Country Link
US (2) US11746107B2 (https=)
EP (1) EP4041726B8 (https=)
JP (1) JP7697933B2 (https=)
KR (1) KR20220069008A (https=)
CN (1) CN114466845B (https=)
AU (1) AU2020356534B2 (https=)
BR (1) BR112022005420A2 (https=)
CA (1) CA3155177A1 (https=)
ES (1) ES3056105T3 (https=)
IL (1) IL291569B2 (https=)
MX (1) MX2022002881A (https=)
PH (1) PH12022550713A1 (https=)
PL (1) PL4041726T3 (https=)
TW (3) TWI769532B (https=)
WO (1) WO2021059220A1 (https=)
ZA (1) ZA202204542B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022002881A (es) 2019-09-25 2022-06-08 Oncoarendi Therapeutics Sa Proceso para la produccion de 5-(4-((2s,5s)-5-(4-clorobencil)-2-me tilmorfolino)piperidin-1-il)-1h-1,2,4-triazol-3-amina.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2802530B1 (fr) * 1999-12-17 2002-02-22 Sanofi Synthelabo Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
ATE354568T1 (de) * 2000-08-08 2007-03-15 Ortho Mcneil Pharm Inc Nicht-imidazol aryloxypiperidine als h3 rezeptor liganden
PE20142366A1 (es) * 2012-05-30 2015-01-10 Hoffmann La Roche Compuestos triazolo como inhibidores de pde 10
EP3082805B1 (en) * 2013-12-20 2020-02-05 Institute for Drug Discovery, LLC Substituted amino triazoles, and methods using same
US9440953B2 (en) 2014-12-19 2016-09-13 OncoArendi Therapeutics Sp. z o.o. Substituted amino triazoles useful as acidic mammalian chitinase inhibitors
GB201513740D0 (en) * 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonist
PL415078A1 (pl) * 2015-09-04 2017-03-13 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Podstawione aminotriazole przydatne jako inhibitory kwaśnej chitynazy ssaków
MX2022000306A (es) 2019-07-15 2022-03-11 Oncoarendi Therapeutics Sa Amino triazoles sustituidos utiles como inhibidores de quitinasa.
MX2022002881A (es) 2019-09-25 2022-06-08 Oncoarendi Therapeutics Sa Proceso para la produccion de 5-(4-((2s,5s)-5-(4-clorobencil)-2-me tilmorfolino)piperidin-1-il)-1h-1,2,4-triazol-3-amina.

Similar Documents

Publication Publication Date Title
TWI518081B (zh) 1-triazole-2-butanol derivative
JP6832946B2 (ja) キナーゼ阻害剤およびその中間体の調製方法
US20100076196A1 (en) Process for the preparation of iloperidone
US11739057B2 (en) Polymorphic forms of Belinostat and processes for preparation thereof
CN103649055A (zh) 用于制备吡唑衍生物的方法
JP6985179B2 (ja) プロリンアミド化合物の製造方法
JP2022549863A5 (https=)
ES2587581T3 (es) Un procedimiento para la preparación de base de imatinib
KR20140013232A (ko) Ｎ-(2-히드록시에틸)니코틴아미드 및 니코란딜의 제조방법
US12319677B2 (en) Process for the production of 5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methyl-morpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine
US10640467B2 (en) Process for preparing 2-(1-(tert-butoxycarbonyl)piperidine-4-yl)benzoic acid
KR101123281B1 (ko) 치환된 벤즈아미드 유도체 및 그의 약제학상 허용되는 염의제조방법
RU2592696C2 (ru) Замещенные фенилсодержащие соединения
US6248888B1 (en) Process for the preparation of terazosin hydrochloride dihydrate
CA3214107A1 (en) New process for the synthesis of 5-{5-chloro-2-[(3s)-3- [(morpholin-4-yl)methyl]-3,4-dihydroisoquinoline-2(1h)- carbonyl]phenyl}-1,2-dimethyl-1h-pyrrole-3-carboxylic acid derivatives and its application for the production of pharmaceutical compounds
HK40080939A (en) Process for the production of 5-(4-((2 s,5 s)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1 h-1,2,4-triazol-3-amine
HK40080939B (en) Process for the production of 5-(4-((2 s,5 s)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1 h-1,2,4-triazol-3-amine
WO2014045294A1 (en) A novel process for the preparation of rosuvastatin calcium using novel intermediates