JP2022547416A5 - - Google Patents
Info
- Publication number
- JP2022547416A5 JP2022547416A5 JP2022513059A JP2022513059A JP2022547416A5 JP 2022547416 A5 JP2022547416 A5 JP 2022547416A5 JP 2022513059 A JP2022513059 A JP 2022513059A JP 2022513059 A JP2022513059 A JP 2022513059A JP 2022547416 A5 JP2022547416 A5 JP 2022547416A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- sequence number
- immune
- responsive
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962892936P | 2019-08-28 | 2019-08-28 | |
| US62/892,936 | 2019-08-28 | ||
| US202062983451P | 2020-02-28 | 2020-02-28 | |
| US62/983,451 | 2020-02-28 | ||
| PCT/EP2020/074071 WO2021038036A1 (en) | 2019-08-28 | 2020-08-28 | B CELL TARGETED PARALLEL CAR (pCAR) THERAPEUTIC AGENTS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022547416A JP2022547416A (ja) | 2022-11-14 |
| JP2022547416A5 true JP2022547416A5 (https=) | 2023-09-04 |
| JP7723420B2 JP7723420B2 (ja) | 2025-08-14 |
Family
ID=72560541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513059A Active JP7723420B2 (ja) | 2019-08-28 | 2020-08-28 | Ｂ細胞標的化並列ＣＡＲ（ｐＣＡＲ）治療的薬剤 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12534507B2 (https=) |
| EP (1) | EP4021485A1 (https=) |
| JP (1) | JP7723420B2 (https=) |
| CN (1) | CN114641308A (https=) |
| WO (1) | WO2021038036A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019377461A1 (en) * | 2018-11-06 | 2021-05-27 | Washington University | Chimeric antigen receptor memory-like (CARML) NK cells and methods of making and using same |
| GB201900858D0 (en) * | 2019-01-22 | 2019-03-13 | Price Nicola Kaye | Receptors providing targeted costimulation for adoptive cell therapy |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| EP4021485A1 (en) | 2019-08-28 | 2022-07-06 | King's College London | B cell targeted parallel car (pcar) therapeutic agents |
| CA3178900A1 (en) * | 2020-06-11 | 2021-12-16 | Marc MARTINEZ-LLORDELLA | Trem2 chimeric receptor |
| JP2023549079A (ja) * | 2020-10-30 | 2023-11-22 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 二重標的化キメラ抗原受容体 |
| CA3213040A1 (en) * | 2021-03-22 | 2022-09-29 | Michel Sadelain | Cd38 chimeric co-stimulating receptor and uses thereof |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000034309A1 (en) * | 1998-12-04 | 2000-06-15 | Dana-Farber Cancer Institute, Inc. | Cloning and characterization of a cd2 binding protein (cd2bp2) |
| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| US7446190B2 (en) | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
| JP2009541275A (ja) * | 2006-06-22 | 2009-11-26 | ノボ・ノルデイスク・エー／エス | 二重特異性抗体の生産 |
| KR20110128876A (ko) | 2009-02-16 | 2011-11-30 | 바이오렉스 쎄라퓨틱스, 인코포레이티드 | 인간화된 항-ｃｄ20 항체 및 이용 방법 |
| US9845362B2 (en) * | 2010-10-08 | 2017-12-19 | The University Of North Carolina At Charlotte | Compositions comprising chimeric antigen receptors, T cells comprising the same, and methods of using the same |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| MX370148B (es) * | 2012-10-02 | 2019-12-03 | Memorial Sloan Kettering Cancer Center | Composiciones y su uso para inmunoterapia. |
| UY35468A (es) * | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| CA2935748A1 (en) | 2014-02-25 | 2015-09-03 | Immunomedics, Inc. | Humanized rfb4 anti-cd22 antibody |
| PL3180363T3 (pl) * | 2014-08-15 | 2020-02-28 | Merck Patent Gmbh | Białka fuzyjne immunoglobulin sirp-alfa |
| GB201503742D0 (en) | 2015-03-05 | 2015-04-22 | Ucl Business Plc | Chimeric antigen receptor |
| GB201513540D0 (en) | 2015-07-31 | 2015-09-16 | King S College London | Therapeutic agents |
| KR20230148844A (ko) * | 2016-03-29 | 2023-10-25 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
| AU2018257894A1 (en) | 2017-04-24 | 2019-10-31 | Kite Pharma, Inc. | Humanized antigen-binding domains against CD19 and methods of use |
| CN108220247A (zh) * | 2018-03-20 | 2018-06-29 | 杭州史迪姆生物科技有限公司 | 一种双car-t细胞及其制备方法和应用 |
| CN109485732B (zh) * | 2018-12-20 | 2021-09-24 | 四川大学华西医院 | 基因工程修饰的双靶点嵌合抗原受体及其用途 |
| EP4021485A1 (en) | 2019-08-28 | 2022-07-06 | King's College London | B cell targeted parallel car (pcar) therapeutic agents |
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2020
- 2020-08-28 EP EP20774886.4A patent/EP4021485A1/en active Pending
- 2020-08-28 US US17/638,742 patent/US12534507B2/en active Active
- 2020-08-28 WO PCT/EP2020/074071 patent/WO2021038036A1/en not_active Ceased
- 2020-08-28 CN CN202080076360.3A patent/CN114641308A/zh active Pending
- 2020-08-28 JP JP2022513059A patent/JP7723420B2/ja active Active