JP2022546408A5 - - Google Patents

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Publication number
JP2022546408A5
JP2022546408A5 JP2022513155A JP2022513155A JP2022546408A5 JP 2022546408 A5 JP2022546408 A5 JP 2022546408A5 JP 2022513155 A JP2022513155 A JP 2022513155A JP 2022513155 A JP2022513155 A JP 2022513155A JP 2022546408 A5 JP2022546408 A5 JP 2022546408A5
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JP
Japan
Prior art keywords
double
stranded rna
rna stem
nucleic acid
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022513155A
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English (en)
Japanese (ja)
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JP2022546408A (ja
JP7737152B2 (ja
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Priority claimed from PCT/US2020/048561 external-priority patent/WO2021041924A2/en
Publication of JP2022546408A publication Critical patent/JP2022546408A/ja
Publication of JP2022546408A5 publication Critical patent/JP2022546408A5/ja
Priority to JP2025073295A priority Critical patent/JP2025118711A/ja
Application granted granted Critical
Publication of JP7737152B2 publication Critical patent/JP7737152B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022513155A 2019-08-30 2020-08-28 遺伝子発現を調節するためのシステム Active JP7737152B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025073295A JP2025118711A (ja) 2019-08-30 2025-04-25 遺伝子発現を調節するためのシステム

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962894611P 2019-08-30 2019-08-30
US62/894,611 2019-08-30
US201962904635P 2019-09-23 2019-09-23
US62/904,635 2019-09-23
US202063043504P 2020-06-24 2020-06-24
US63/043,504 2020-06-24
PCT/US2020/048561 WO2021041924A2 (en) 2019-08-30 2020-08-28 System for regulating gene expression

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025073295A Division JP2025118711A (ja) 2019-08-30 2025-04-25 遺伝子発現を調節するためのシステム

Publications (3)

Publication Number Publication Date
JP2022546408A JP2022546408A (ja) 2022-11-04
JP2022546408A5 true JP2022546408A5 (https=) 2023-09-05
JP7737152B2 JP7737152B2 (ja) 2025-09-10

Family

ID=74683442

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022513155A Active JP7737152B2 (ja) 2019-08-30 2020-08-28 遺伝子発現を調節するためのシステム
JP2025073295A Pending JP2025118711A (ja) 2019-08-30 2025-04-25 遺伝子発現を調節するためのシステム

Family Applications After (1)

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JP2025073295A Pending JP2025118711A (ja) 2019-08-30 2025-04-25 遺伝子発現を調節するためのシステム

Country Status (11)

Country Link
US (1) US20220290147A1 (https=)
EP (1) EP4022065A4 (https=)
JP (2) JP7737152B2 (https=)
KR (1) KR20220049619A (https=)
CN (1) CN115279902A (https=)
AU (1) AU2020335909A1 (https=)
BR (1) BR112022003512A2 (https=)
CA (1) CA3152513A1 (https=)
IL (1) IL290944A (https=)
MX (1) MX2022002390A (https=)
WO (1) WO2021041924A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102904879B1 (ko) 2015-11-12 2025-12-30 베이롤 칼리지 오브 메드신 폴리아데닐화의 압타머 매개된 조정을 통한 포유류 유전자 발현의 외인성 제어
AU2022327174A1 (en) 2021-08-11 2024-02-15 Sana Biotechnology, Inc. Inducible systems for altering gene expression in hypoimmunogenic cells

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
CA2559280A1 (en) 2004-03-15 2005-09-29 Biogen Idec Ma Inc. Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing
WO2005106035A2 (en) * 2004-04-09 2005-11-10 Cornell Research Foundation, Inc. Modular design and construction of nucleic acid molecules, aptamer-derived nucleic acid constructs, rna scaffolds, their expression, and methods of use
WO2005116204A1 (ja) * 2004-05-11 2005-12-08 Rnai Co., Ltd. Rna干渉を生じさせるポリヌクレオチド、および、これを用いた遺伝子発現抑制方法
US7825229B2 (en) * 2005-03-25 2010-11-02 Rosetta Genomics Ltd. Lung cancer-related nucleic acids
US8178503B2 (en) * 2006-03-03 2012-05-15 International Business Machines Corporation Ribonucleic acid interference molecules and binding sites derived by analyzing intergenic and intronic regions of genomes
US20150284738A1 (en) * 2006-12-29 2015-10-08 Rodina Holding S.A. Artificial dna sequence with optimized leader function in 5' (5'-utr) for the improved expression of heterologous proteins in plants
CN103108952A (zh) * 2010-09-01 2013-05-15 日本电气株式会社 检测目标物质的方法以及用于所述方法中的适体组、传感器和装置
EP2622084A1 (en) * 2010-10-01 2013-08-07 R1 B3 Holding B.V. Regulation of translation of expressed genes
WO2013119371A2 (en) * 2012-02-10 2013-08-15 The Board Of Trustees Of The Leland Stanford Junior University Mini-intronic plasmid vectors
US20150141320A1 (en) * 2012-05-16 2015-05-21 Rana Therapeutics, Inc. Compositions and methods for modulating gene expression
US9567581B2 (en) * 2012-08-07 2017-02-14 The General Hospital Corporation Selective reactivation of genes on the inactive X chromosome
KR102699584B1 (ko) 2015-02-02 2024-08-28 메이라지티엑스 유케이 Ii 리미티드 대안적 스플라이싱의 압타머 매개 조절에 의한 유전자 발현 제어
EP3268481B1 (en) * 2015-03-11 2020-05-27 The United States of America, as represented by The Secretary, Department of Health and Human Services Rpgr vectors for treating x-linked retinitis pigmentosa
KR102904879B1 (ko) * 2015-11-12 2025-12-30 베이롤 칼리지 오브 메드신 폴리아데닐화의 압타머 매개된 조정을 통한 포유류 유전자 발현의 외인성 제어

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