BR112022003512A2 - Sistema para regular expressão gênica - Google Patents
Sistema para regular expressão gênicaInfo
- Publication number
- BR112022003512A2 BR112022003512A2 BR112022003512A BR112022003512A BR112022003512A2 BR 112022003512 A2 BR112022003512 A2 BR 112022003512A2 BR 112022003512 A BR112022003512 A BR 112022003512A BR 112022003512 A BR112022003512 A BR 112022003512A BR 112022003512 A2 BR112022003512 A2 BR 112022003512A2
- Authority
- BR
- Brazil
- Prior art keywords
- gene expression
- regulate gene
- regulate
- regulation
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962894611P | 2019-08-30 | 2019-08-30 | |
| US201962904635P | 2019-09-23 | 2019-09-23 | |
| US202063043504P | 2020-06-24 | 2020-06-24 | |
| PCT/US2020/048561 WO2021041924A2 (en) | 2019-08-30 | 2020-08-28 | System for regulating gene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022003512A2 true BR112022003512A2 (pt) | 2022-05-17 |
Family
ID=74683442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022003512A BR112022003512A2 (pt) | 2019-08-30 | 2020-08-28 | Sistema para regular expressão gênica |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220290147A1 (https=) |
| EP (1) | EP4022065A4 (https=) |
| JP (2) | JP7737152B2 (https=) |
| KR (1) | KR20220049619A (https=) |
| CN (1) | CN115279902A (https=) |
| AU (1) | AU2020335909A1 (https=) |
| BR (1) | BR112022003512A2 (https=) |
| CA (1) | CA3152513A1 (https=) |
| IL (1) | IL290944A (https=) |
| MX (1) | MX2022002390A (https=) |
| WO (1) | WO2021041924A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102904879B1 (ko) | 2015-11-12 | 2025-12-30 | 베이롤 칼리지 오브 메드신 | 폴리아데닐화의 압타머 매개된 조정을 통한 포유류 유전자 발현의 외인성 제어 |
| AU2022327174A1 (en) | 2021-08-11 | 2024-02-15 | Sana Biotechnology, Inc. | Inducible systems for altering gene expression in hypoimmunogenic cells |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003295600A1 (en) * | 2002-11-14 | 2004-06-15 | Dharmacon, Inc. | Functional and hyperfunctional sirna |
| CA2559280A1 (en) | 2004-03-15 | 2005-09-29 | Biogen Idec Ma Inc. | Methods and constructs for expressing polypeptide multimers in eukaryotic cells using alternative splicing |
| WO2005106035A2 (en) * | 2004-04-09 | 2005-11-10 | Cornell Research Foundation, Inc. | Modular design and construction of nucleic acid molecules, aptamer-derived nucleic acid constructs, rna scaffolds, their expression, and methods of use |
| WO2005116204A1 (ja) * | 2004-05-11 | 2005-12-08 | Rnai Co., Ltd. | Ｒｎａ干渉を生じさせるポリヌクレオチド、および、これを用いた遺伝子発現抑制方法 |
| US7825229B2 (en) * | 2005-03-25 | 2010-11-02 | Rosetta Genomics Ltd. | Lung cancer-related nucleic acids |
| US8178503B2 (en) * | 2006-03-03 | 2012-05-15 | International Business Machines Corporation | Ribonucleic acid interference molecules and binding sites derived by analyzing intergenic and intronic regions of genomes |
| US20150284738A1 (en) * | 2006-12-29 | 2015-10-08 | Rodina Holding S.A. | Artificial dna sequence with optimized leader function in 5' (5'-utr) for the improved expression of heterologous proteins in plants |
| CN103108952A (zh) * | 2010-09-01 | 2013-05-15 | 日本电气株式会社 | 检测目标物质的方法以及用于所述方法中的适体组、传感器和装置 |
| EP2622084A1 (en) * | 2010-10-01 | 2013-08-07 | R1 B3 Holding B.V. | Regulation of translation of expressed genes |
| WO2013119371A2 (en) * | 2012-02-10 | 2013-08-15 | The Board Of Trustees Of The Leland Stanford Junior University | Mini-intronic plasmid vectors |
| US20150141320A1 (en) * | 2012-05-16 | 2015-05-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating gene expression |
| US9567581B2 (en) * | 2012-08-07 | 2017-02-14 | The General Hospital Corporation | Selective reactivation of genes on the inactive X chromosome |
| KR102699584B1 (ko) | 2015-02-02 | 2024-08-28 | 메이라지티엑스 유케이 Ii 리미티드 | 대안적 스플라이싱의 압타머 매개 조절에 의한 유전자 발현 제어 |
| EP3268481B1 (en) * | 2015-03-11 | 2020-05-27 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Rpgr vectors for treating x-linked retinitis pigmentosa |
| KR102904879B1 (ko) * | 2015-11-12 | 2025-12-30 | 베이롤 칼리지 오브 메드신 | 폴리아데닐화의 압타머 매개된 조정을 통한 포유류 유전자 발현의 외인성 제어 |
-
2020
- 2020-08-28 CN CN202080072368.2A patent/CN115279902A/zh active Pending
- 2020-08-28 MX MX2022002390A patent/MX2022002390A/es unknown
- 2020-08-28 JP JP2022513155A patent/JP7737152B2/ja active Active
- 2020-08-28 KR KR1020227010164A patent/KR20220049619A/ko active Pending
- 2020-08-28 WO PCT/US2020/048561 patent/WO2021041924A2/en not_active Ceased
- 2020-08-28 BR BR112022003512A patent/BR112022003512A2/pt active Search and Examination
- 2020-08-28 EP EP20856728.9A patent/EP4022065A4/en active Pending
- 2020-08-28 CA CA3152513A patent/CA3152513A1/en active Pending
- 2020-08-28 AU AU2020335909A patent/AU2020335909A1/en active Pending
- 2020-08-28 US US17/638,619 patent/US20220290147A1/en active Pending
-
2022
- 2022-02-27 IL IL290944A patent/IL290944A/en unknown
-
2025
- 2025-04-25 JP JP2025073295A patent/JP2025118711A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020335909A1 (en) | 2022-04-14 |
| US20220290147A1 (en) | 2022-09-15 |
| IL290944A (en) | 2022-04-01 |
| WO2021041924A2 (en) | 2021-03-04 |
| MX2022002390A (es) | 2022-05-13 |
| JP2025118711A (ja) | 2025-08-13 |
| JP2022546408A (ja) | 2022-11-04 |
| CN115279902A (zh) | 2022-11-01 |
| KR20220049619A (ko) | 2022-04-21 |
| EP4022065A2 (en) | 2022-07-06 |
| JP7737152B2 (ja) | 2025-09-10 |
| WO2021041924A3 (en) | 2021-04-08 |
| EP4022065A4 (en) | 2024-02-14 |
| CA3152513A1 (en) | 2021-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
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