JP2022545364A5 - - Google Patents

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Publication number
JP2022545364A5
JP2022545364A5 JP2022508918A JP2022508918A JP2022545364A5 JP 2022545364 A5 JP2022545364 A5 JP 2022545364A5 JP 2022508918 A JP2022508918 A JP 2022508918A JP 2022508918 A JP2022508918 A JP 2022508918A JP 2022545364 A5 JP2022545364 A5 JP 2022545364A5
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JP
Japan
Prior art keywords
carboxamide
isopropylamino
methylbutyl
hydroxy
fluoro
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Granted
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JP2022508918A
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English (en)
Japanese (ja)
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JP2022545364A (ja
JP7629905B2 (ja
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Priority claimed from PCT/US2020/045831 external-priority patent/WO2021030379A1/en
Publication of JP2022545364A publication Critical patent/JP2022545364A/ja
Publication of JP2022545364A5 publication Critical patent/JP2022545364A5/ja
Application granted granted Critical
Publication of JP7629905B2 publication Critical patent/JP7629905B2/ja
Active legal-status Critical Current
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JP2022508918A 2019-08-13 2020-08-12 Ｉｒａｋ４阻害剤として有用な二環ヘテロアリール化合物 Active JP7629905B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962885852P 2019-08-13 2019-08-13
US62/885,852 2019-08-13
PCT/US2020/045831 WO2021030379A1 (en) 2019-08-13 2020-08-12 Bicyclic heteroaryl compounds useful as irak4 inhibitors

Publications (3)

Publication Number Publication Date
JP2022545364A JP2022545364A (ja) 2022-10-27
JP2022545364A5 true JP2022545364A5 (https=) 2023-08-10
JP7629905B2 JP7629905B2 (ja) 2025-02-14

Family

ID=72243202

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022508918A Active JP7629905B2 (ja) 2019-08-13 2020-08-12 Ｉｒａｋ４阻害剤として有用な二環ヘテロアリール化合物

Country Status (7)

Country Link
US (1) US12570659B2 (https=)
EP (1) EP4013758B1 (https=)
JP (1) JP7629905B2 (https=)
KR (1) KR102930924B1 (https=)
CN (1) CN114206874B (https=)
ES (1) ES3059914T3 (https=)
WO (1) WO2021030379A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12269822B2 (en) 2018-07-09 2025-04-08 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
MX2021011302A (es) 2019-03-19 2022-01-19 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos.
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
US11999742B2 (en) 2021-11-01 2024-06-04 Boehringer Ingelheim Vetmedica Gmbh Substituted pyrrolo[1,2-b]pyridazines as anthelmintics
TW202330546A (zh) * 2021-12-31 2023-08-01 香港商愛科諾生物醫藥(香港)有限公司 具有irak4抑制活性的化合物，包含其的藥物組合物，及其應用
CN120093763A (zh) * 2025-03-25 2025-06-06 上海天龙生物科技有限公司 治疗前列腺疾病和腺体类散结节的药物组合物及其应用

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MXPA05007503A (es) 2003-01-17 2005-09-21 Warner Lambert Co Heterociclicos 2-aminopiridina sustituidos como inhibidores de proliferacion celular.
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JP6215338B2 (ja) 2012-11-08 2017-10-18 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ キナーゼモジュレーターとして有用な二環式ヘテロ環置換ピリジル化合物
KR102233252B1 (ko) 2012-11-08 2021-03-26 브리스톨-마이어스 스큅 컴퍼니 ＩＬ-12, ＩＬ-23 및/또는 ＩＦＮα 반응의 조절제로서 유용한 알킬-아미드-치환된 피리딜 화합물
TWI582077B (zh) 2013-11-07 2017-05-11 必治妥美雅史谷比公司 作爲ＩＬ－１２、ＩＬ－２３及／或ＩＦＮα反應調節劑之經烷基－醯胺取代之吡啶化合物
LT3466955T (lt) 2014-01-13 2021-02-25 Aurigene Discovery Technologies Limited Oksazol[4,5-b]piridino ir tiazol[4,5-b]piridino darinių, kaip irak4 inhibitorių, skirtų vėžio gydymui, gamybos būdas
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WO2016144849A1 (en) 2015-03-12 2016-09-15 Merck Sharp & Dohme Corp. Thienopyrazine inhibitors of irak4 activity
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HUE053705T2 (hu) 2015-08-27 2021-07-28 Pfizer Biciklusos kondenzált heteroaril- vagy aril- vegyületek IRAK4 modulátorokként
PT3621960T (pt) 2017-05-11 2021-09-16 Bristol Myers Squibb Co Tienopiridinas e benzotiofenos úteis como inibidores de irak4

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