JP2022542574A5 - - Google Patents
Info
- Publication number
- JP2022542574A5 JP2022542574A5 JP2022504589A JP2022504589A JP2022542574A5 JP 2022542574 A5 JP2022542574 A5 JP 2022542574A5 JP 2022504589 A JP2022504589 A JP 2022504589A JP 2022504589 A JP2022504589 A JP 2022504589A JP 2022542574 A5 JP2022542574 A5 JP 2022542574A5
- Authority
- JP
- Japan
- Prior art keywords
- her2
- amino acid
- seq
- acid sequence
- bispecific antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025131324A JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962878951P | 2019-07-26 | 2019-07-26 | |
| US62/878,951 | 2019-07-26 | ||
| US202063024608P | 2020-05-14 | 2020-05-14 | |
| US63/024,608 | 2020-05-14 | ||
| PCT/KR2020/009871 WO2021020846A1 (en) | 2019-07-26 | 2020-07-27 | Anti-her2/anti-4-1bb bispecific antibody and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025131324A Division JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542574A JP2022542574A (ja) | 2022-10-05 |
| JP2022542574A5 true JP2022542574A5 (enExample) | 2023-08-07 |
| JP7725446B2 JP7725446B2 (ja) | 2025-08-19 |
Family
ID=74190718
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022504589A Active JP7725446B2 (ja) | 2019-07-26 | 2020-07-27 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
| JP2025131324A Pending JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025131324A Pending JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12240913B2 (enExample) |
| EP (1) | EP4004054A4 (enExample) |
| JP (2) | JP7725446B2 (enExample) |
| KR (2) | KR102820082B1 (enExample) |
| CN (2) | CN114206941B (enExample) |
| AU (1) | AU2020320233A1 (enExample) |
| BR (1) | BR112022001336A8 (enExample) |
| CA (1) | CA3147423A1 (enExample) |
| MX (1) | MX2022001022A (enExample) |
| WO (1) | WO2021020846A1 (enExample) |
| ZA (1) | ZA202200906B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021008870A2 (pt) | 2019-08-12 | 2021-11-30 | Abl Bio Inc | Anticorpo, um ou mais polinucleotídeos, composição, uso do anticorpo, e, método para tratar câncer. |
| KR20220145859A (ko) * | 2020-02-28 | 2022-10-31 | 상하이 헨리우스 바이오테크, 인크. | 항cd137 작제물, 다중 특이적 항체 및 그 용도 |
| KR20230042524A (ko) * | 2020-08-07 | 2023-03-28 | 주식회사 유틸렉스 | 항-her2 / 항-4-1bb 이중특이적 항체 및 이의 용도 |
| JP2024504388A (ja) * | 2021-01-25 | 2024-01-31 | ユーハン・コーポレイション | 抗４－１ｂｂ／抗ｈｅｒ２二重特異性抗体の精製方法 |
| CA3237165A1 (en) * | 2021-11-19 | 2023-05-25 | Jeng-Horng Her | Bispecific antibodies targeting cd137 and uses thereof for anti-cancer immunotherapy |
| JP2025512915A (ja) * | 2022-04-07 | 2025-04-22 | ユハン コーポレーション | Ｈｅｒ２の発現レベルが低いがんを治療又は予防するための薬学的組成物 |
| KR20250148463A (ko) * | 2024-04-03 | 2025-10-14 | 주식회사유한양행 | 담도암의 치료를 위한 항-her2/항-4-1bb 이중 특이 항체 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100694508B1 (ko) * | 2005-05-24 | 2007-03-13 | 울산대학교 산학협력단 | Ｈｂｂｋ４항체를 포함하는 암 질환 치료용 약학조성물및 이를 이용한 암의 면역치료 방법 |
| DK2699598T3 (en) * | 2011-04-19 | 2019-04-23 | Pfizer | COMBINATIONS OF ANTI-4-1BB ANTIBODIES AND ADCC-INducing ANTIBODIES FOR TREATMENT OF CANCER |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| JP2018510652A (ja) | 2015-03-18 | 2018-04-19 | ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ | Ｈｅｒ２／ｅｒｂｂ２キメラ抗原受容体 |
| JP6783797B2 (ja) | 2015-05-04 | 2020-11-11 | ピエリス ファーマシューティカルズ ゲーエムベーハー | 抗がん融合ポリペプチド |
| CN108064246A (zh) * | 2015-06-15 | 2018-05-22 | 基因泰克公司 | 抗体和免疫结合物 |
| JP2019513373A (ja) | 2016-03-31 | 2019-05-30 | ネオン セラピューティクス， インコーポレイテッド | ネオ抗原およびその使用方法 |
| EP3445788B1 (en) * | 2016-04-22 | 2022-01-19 | Alligator Bioscience AB | Novel bispecific polypeptides against cd137 |
| JP2019532997A (ja) * | 2016-11-03 | 2019-11-14 | ジュノー セラピューティクス インコーポレイテッド | Ｔ細胞療法とｂｔｋ阻害剤との併用療法 |
| AU2018224094B2 (en) * | 2017-02-24 | 2025-04-17 | Macrogenics, Inc. | Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof |
| EP3655439A1 (en) | 2017-07-20 | 2020-05-27 | Aptevo Research and Development LLC | Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods |
| CN113286825B (zh) * | 2018-11-30 | 2024-06-18 | 爱必乐生物公司 | 抗pd-l1/抗4-1bb双特异性抗体及其用途 |
-
2020
- 2020-07-27 EP EP20848659.7A patent/EP4004054A4/en active Pending
- 2020-07-27 CN CN202080054005.6A patent/CN114206941B/zh active Active
- 2020-07-27 BR BR112022001336A patent/BR112022001336A8/pt unknown
- 2020-07-27 KR KR1020227006642A patent/KR102820082B1/ko active Active
- 2020-07-27 CN CN202410786028.6A patent/CN118638240A/zh active Pending
- 2020-07-27 US US16/939,536 patent/US12240913B2/en active Active
- 2020-07-27 WO PCT/KR2020/009871 patent/WO2021020846A1/en not_active Ceased
- 2020-07-27 AU AU2020320233A patent/AU2020320233A1/en active Pending
- 2020-07-27 KR KR1020257019038A patent/KR20250090381A/ko active Pending
- 2020-07-27 MX MX2022001022A patent/MX2022001022A/es unknown
- 2020-07-27 CA CA3147423A patent/CA3147423A1/en active Pending
- 2020-07-27 JP JP2022504589A patent/JP7725446B2/ja active Active
-
2022
- 2022-01-19 ZA ZA2022/00906A patent/ZA202200906B/en unknown
-
2025
- 2025-01-23 US US19/034,755 patent/US20250163180A1/en active Pending
- 2025-08-06 JP JP2025131324A patent/JP2025179060A/ja active Pending