JP2022542574A5 - - Google Patents
Info
- Publication number
- JP2022542574A5 JP2022542574A5 JP2022504589A JP2022504589A JP2022542574A5 JP 2022542574 A5 JP2022542574 A5 JP 2022542574A5 JP 2022504589 A JP2022504589 A JP 2022504589A JP 2022504589 A JP2022504589 A JP 2022504589A JP 2022542574 A5 JP2022542574 A5 JP 2022542574A5
- Authority
- JP
- Japan
- Prior art keywords
- her2
- amino acid
- seq
- acid sequence
- bispecific antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025131324A JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962878951P | 2019-07-26 | 2019-07-26 | |
| US62/878,951 | 2019-07-26 | ||
| US202063024608P | 2020-05-14 | 2020-05-14 | |
| US63/024,608 | 2020-05-14 | ||
| PCT/KR2020/009871 WO2021020846A1 (en) | 2019-07-26 | 2020-07-27 | Anti-her2/anti-4-1bb bispecific antibody and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025131324A Division JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542574A JP2022542574A (ja) | 2022-10-05 |
| JP2022542574A5 true JP2022542574A5 (enExample) | 2023-08-07 |
| JP7725446B2 JP7725446B2 (ja) | 2025-08-19 |
Family
ID=74190718
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022504589A Active JP7725446B2 (ja) | 2019-07-26 | 2020-07-27 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
| JP2025131324A Pending JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025131324A Pending JP2025179060A (ja) | 2019-07-26 | 2025-08-06 | 抗ｈｅｒ２／抗４－１ｂｂ二重特異性抗体及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12240913B2 (enExample) |
| EP (1) | EP4004054A4 (enExample) |
| JP (2) | JP7725446B2 (enExample) |
| KR (2) | KR102820082B1 (enExample) |
| CN (2) | CN118638240A (enExample) |
| AU (1) | AU2020320233A1 (enExample) |
| BR (1) | BR112022001336A8 (enExample) |
| CA (1) | CA3147423A1 (enExample) |
| MX (1) | MX2022001022A (enExample) |
| WO (1) | WO2021020846A1 (enExample) |
| ZA (1) | ZA202200906B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11261259B2 (en) | 2019-08-12 | 2022-03-01 | I-Mab Biopharma Us Limited | Anti-claudin 18.2 and anti-4-1BB bispecific antibodies and uses thereof |
| KR20220145859A (ko) * | 2020-02-28 | 2022-10-31 | 상하이 헨리우스 바이오테크, 인크. | 항cd137 작제물, 다중 특이적 항체 및 그 용도 |
| WO2022029496A1 (en) * | 2020-08-07 | 2022-02-10 | Eutilex Co., Ltd. | Anti-her2 / anti-4-1bb bispecific antibodies and uses thereof |
| JP7875865B2 (ja) * | 2021-01-25 | 2026-06-18 | ユーハン・コーポレイション | 抗４－１ｂｂ／抗ｈｅｒ２二重特異性抗体の精製方法 |
| IL311003A (en) | 2021-08-25 | 2024-04-01 | Denali Therapeutics Inc | Anti-2HER antibodies and methods of using them |
| CA3237165A1 (en) * | 2021-11-19 | 2023-05-25 | Jeng-Horng Her | Bispecific antibodies targeting cd137 and uses thereof for anti-cancer immunotherapy |
| EP4504790A4 (en) * | 2022-04-07 | 2026-04-08 | Yuhan Corp | Pharmaceutical composition for treating or preventing cancer with low HER2 expression |
| KR20250148463A (ko) * | 2024-04-03 | 2025-10-14 | 주식회사유한양행 | 담도암의 치료를 위한 항-her2/항-4-1bb 이중 특이 항체 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100694508B1 (ko) * | 2005-05-24 | 2007-03-13 | 울산대학교 산학협력단 | Ｈｂｂｋ４항체를 포함하는 암 질환 치료용 약학조성물및 이를 이용한 암의 면역치료 방법 |
| US20140178368A1 (en) * | 2011-04-19 | 2014-06-26 | Leslie Lynne SHARP | Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| WO2016149665A1 (en) * | 2015-03-18 | 2016-09-22 | Baylor College Of Medicine | Her2/erbb2 chimeric antigen receptor |
| RU2727165C2 (ru) * | 2015-05-04 | 2020-07-21 | ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ | Слитый полипептид с противораковой активностью |
| US10017577B2 (en) * | 2015-06-15 | 2018-07-10 | Genentech, Inc. | Antibodies and immunoconjugates |
| SG11201808196UA (en) * | 2016-03-31 | 2018-10-30 | Neon Therapeutics Inc | Neoantigens and methods of their use |
| BR112018071612A2 (pt) * | 2016-04-22 | 2019-02-19 | Alligator Bioscience Ab | polipeptídeos biespecíficos inovadores contra cd137 |
| CA3042049A1 (en) * | 2016-11-03 | 2018-05-11 | Juno Therapeutics, Inc. | Combination therapy of a t cell therapy and a btk inhibitor |
| BR112019017628A2 (pt) * | 2017-02-24 | 2020-07-07 | Macrogenics, Inc. | molécula de ligação a cd137 x ta, composições farmacêuticas, uso da molécula de ligação a cd137 x ta, molécula de ligação a cd137, uso da molécula de ligação a cd137, molécula de ligação a her2/neu, uso da molécula de ligação a her2/neu, e uso de uma composição |
| US11725060B2 (en) | 2017-07-20 | 2023-08-15 | Aptevo Reserch and Development LLC | Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods |
| SG11202105152YA (en) * | 2018-11-30 | 2021-06-29 | Abl Bio Inc | Anti-pd-l1/anti-4-1bb bispecific antibodies and uses thereof |
-
2020
- 2020-07-27 CN CN202410786028.6A patent/CN118638240A/zh active Pending
- 2020-07-27 WO PCT/KR2020/009871 patent/WO2021020846A1/en not_active Ceased
- 2020-07-27 EP EP20848659.7A patent/EP4004054A4/en active Pending
- 2020-07-27 CA CA3147423A patent/CA3147423A1/en active Pending
- 2020-07-27 MX MX2022001022A patent/MX2022001022A/es unknown
- 2020-07-27 KR KR1020227006642A patent/KR102820082B1/ko active Active
- 2020-07-27 JP JP2022504589A patent/JP7725446B2/ja active Active
- 2020-07-27 CN CN202080054005.6A patent/CN114206941B/zh active Active
- 2020-07-27 AU AU2020320233A patent/AU2020320233A1/en active Pending
- 2020-07-27 BR BR112022001336A patent/BR112022001336A8/pt unknown
- 2020-07-27 KR KR1020257019038A patent/KR20250090381A/ko active Pending
- 2020-07-27 US US16/939,536 patent/US12240913B2/en active Active
-
2022
- 2022-01-19 ZA ZA2022/00906A patent/ZA202200906B/en unknown
-
2025
- 2025-01-23 US US19/034,755 patent/US20250163180A1/en active Pending
- 2025-08-06 JP JP2025131324A patent/JP2025179060A/ja active Pending