JP2022542670A5 - - Google Patents

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Publication number
JP2022542670A5
JP2022542670A5 JP2022504629A JP2022504629A JP2022542670A5 JP 2022542670 A5 JP2022542670 A5 JP 2022542670A5 JP 2022504629 A JP2022504629 A JP 2022504629A JP 2022504629 A JP2022504629 A JP 2022504629A JP 2022542670 A5 JP2022542670 A5 JP 2022542670A5
Authority
JP
Japan
Prior art keywords
egfr
amino acid
seq
acid sequence
bispecific antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022504629A
Other languages
English (en)
Japanese (ja)
Other versions
JP7738545B2 (ja
JP2022542670A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2020/009870 external-priority patent/WO2021020845A1/en
Publication of JP2022542670A publication Critical patent/JP2022542670A/ja
Publication of JP2022542670A5 publication Critical patent/JP2022542670A5/ja
Priority to JP2025145010A priority Critical patent/JP2026004296A/ja
Application granted granted Critical
Publication of JP7738545B2 publication Critical patent/JP7738545B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022504629A 2019-07-26 2020-07-27 抗egfr/抗4-1bb二重特異性抗体及びその使用 Active JP7738545B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025145010A JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962878977P 2019-07-26 2019-07-26
US62/878,977 2019-07-26
PCT/KR2020/009870 WO2021020845A1 (en) 2019-07-26 2020-07-27 Anti-egfr/anti-4-1bb bispecific antibody and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025145010A Division JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Publications (3)

Publication Number Publication Date
JP2022542670A JP2022542670A (ja) 2022-10-06
JP2022542670A5 true JP2022542670A5 (enExample) 2023-08-03
JP7738545B2 JP7738545B2 (ja) 2025-09-12

Family

ID=74189704

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022504629A Active JP7738545B2 (ja) 2019-07-26 2020-07-27 抗egfr/抗4-1bb二重特異性抗体及びその使用
JP2025145010A Pending JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025145010A Pending JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Country Status (11)

Country Link
US (2) US12168690B2 (enExample)
EP (1) EP4004053A4 (enExample)
JP (2) JP7738545B2 (enExample)
KR (1) KR20220038767A (enExample)
CN (2) CN118221825A (enExample)
AU (1) AU2020320349A1 (enExample)
BR (1) BR112022001329A2 (enExample)
CA (1) CA3147420A1 (enExample)
MX (1) MX2022001027A (enExample)
WO (1) WO2021020845A1 (enExample)
ZA (1) ZA202200905B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11261259B2 (en) 2019-08-12 2022-03-01 I-Mab Biopharma Us Limited Anti-claudin 18.2 and anti-4-1BB bispecific antibodies and uses thereof
WO2022072087A1 (en) * 2020-10-01 2022-04-07 QC Ware Corp. Quantum number preserving circuits for preparing quantum states representing fermions in computational units-based quantum computers
JP7767613B2 (ja) 2021-11-15 2025-11-11 システィミューン,インコーポレイテッド 二重特異性抗体-カンプトテシン薬物複合体及びその製薬的使用
CN118369340A (zh) * 2021-11-25 2024-07-19 盛禾(中国)生物制药有限公司 一种双特异性抗原结合蛋白
EP4504790A4 (en) * 2022-04-07 2026-04-08 Yuhan Corp Pharmaceutical composition for treating or preventing cancer with low HER2 expression
WO2024143643A1 (ko) * 2022-12-30 2024-07-04 앱클론(주) Cd137에 특이적으로 결합하는 어피바디 및 이의 용도
KR20240164748A (ko) * 2023-05-12 2024-11-20 앱클론(주) 항체 또는 그의 항원 결합 단편, 및 어피바디를 포함하는 이중 항원 표적 단백질 복합체
KR102927129B1 (ko) 2025-03-18 2026-02-11 이트너스 주식회사 임직원 공간 산정을 위한 사무 및 부대 시설 면적 계산 솔루션

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69624436T2 (de) 1995-04-08 2003-08-28 Lg Chemical Ltd., Seoul/Soul Humaner 4-1bb spezifischer humaner antikörper und diesen produzierende zellinie
US7288638B2 (en) 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
BRPI0607315B1 (pt) 2005-02-07 2022-05-17 Roche Glycart Ag Molécula de ligação ao antígeno anti-egfr humanizada e seus usos, composição farmacêutica, e método para detectar a presença de egfr em uma amostra
WO2008028686A2 (en) * 2006-09-10 2008-03-13 Glycotope Gmbh Use of human cells of myeloid leukaemia origin for expression of antibodies
US20140178368A1 (en) 2011-04-19 2014-06-26 Leslie Lynne SHARP Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
KR102319582B1 (ko) * 2013-08-16 2021-11-04 메모리얼 슬로안 케터링 캔서 센터 선택적 grp94 저해제 및 이의 용도
US10717783B2 (en) * 2014-12-22 2020-07-21 Zeren Gao Bispecific tetravalent antibodies and methods of making and using thereof
ES2819870T3 (es) 2015-09-30 2021-04-19 Igm Biosciences Inc Moléculas de unión con cadena J modificada
SG11201808196UA (en) 2016-03-31 2018-10-30 Neon Therapeutics Inc Neoantigens and methods of their use
BR112018071612A2 (pt) * 2016-04-22 2019-02-19 Alligator Bioscience Ab polipeptídeos biespecíficos inovadores contra cd137
JP7160833B2 (ja) * 2017-04-13 2022-10-25 サイロパ ビー.ブイ. 抗sirpアルファ抗体
US11725060B2 (en) 2017-07-20 2023-08-15 Aptevo Reserch and Development LLC Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods
JP2021508478A (ja) * 2017-12-28 2021-03-11 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクJulius Maximilians−Universitaet Wuerzburg FcγR非依存性アゴニスト活性がある腫瘍壊死因子(TNF)受容体スーパーファミリー(TNFRSF)受容体活性化抗体融合タンパク質(FcγR非依存性アゴニスト活性があるTNFRSF受容体活性化抗体融合タンパク質;TRAAFFIAA)
EP3880247A4 (en) * 2018-11-13 2022-10-26 JN Biosciences, LLC Bispecific antibodies for activation of immune cells
SG11202105152YA (en) * 2018-11-30 2021-06-29 Abl Bio Inc Anti-pd-l1/anti-4-1bb bispecific antibodies and uses thereof
US11261259B2 (en) * 2019-08-12 2022-03-01 I-Mab Biopharma Us Limited Anti-claudin 18.2 and anti-4-1BB bispecific antibodies and uses thereof
CN115190889A (zh) * 2020-02-28 2022-10-14 上海复宏汉霖生物技术股份有限公司 抗cd137构建体、多特异性抗体及其用途

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