JP2022542670A5 - - Google Patents

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Publication number
JP2022542670A5
JP2022542670A5 JP2022504629A JP2022504629A JP2022542670A5 JP 2022542670 A5 JP2022542670 A5 JP 2022542670A5 JP 2022504629 A JP2022504629 A JP 2022504629A JP 2022504629 A JP2022504629 A JP 2022504629A JP 2022542670 A5 JP2022542670 A5 JP 2022542670A5
Authority
JP
Japan
Prior art keywords
egfr
amino acid
seq
acid sequence
bispecific antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022504629A
Other languages
English (en)
Japanese (ja)
Other versions
JP7738545B2 (ja
JP2022542670A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2020/009870 external-priority patent/WO2021020845A1/en
Publication of JP2022542670A publication Critical patent/JP2022542670A/ja
Publication of JP2022542670A5 publication Critical patent/JP2022542670A5/ja
Priority to JP2025145010A priority Critical patent/JP2026004296A/ja
Application granted granted Critical
Publication of JP7738545B2 publication Critical patent/JP7738545B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022504629A 2019-07-26 2020-07-27 抗egfr/抗4-1bb二重特異性抗体及びその使用 Active JP7738545B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025145010A JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962878977P 2019-07-26 2019-07-26
US62/878,977 2019-07-26
PCT/KR2020/009870 WO2021020845A1 (en) 2019-07-26 2020-07-27 Anti-egfr/anti-4-1bb bispecific antibody and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025145010A Division JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Publications (3)

Publication Number Publication Date
JP2022542670A JP2022542670A (ja) 2022-10-06
JP2022542670A5 true JP2022542670A5 (enExample) 2023-08-03
JP7738545B2 JP7738545B2 (ja) 2025-09-12

Family

ID=74189704

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022504629A Active JP7738545B2 (ja) 2019-07-26 2020-07-27 抗egfr/抗4-1bb二重特異性抗体及びその使用
JP2025145010A Pending JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025145010A Pending JP2026004296A (ja) 2019-07-26 2025-09-02 抗egfr/抗4-1bb二重特異性抗体及びその使用

Country Status (11)

Country Link
US (2) US12168690B2 (enExample)
EP (1) EP4004053A4 (enExample)
JP (2) JP7738545B2 (enExample)
KR (1) KR20220038767A (enExample)
CN (2) CN114450306B (enExample)
AU (1) AU2020320349A1 (enExample)
BR (1) BR112022001329A2 (enExample)
CA (1) CA3147420A1 (enExample)
MX (1) MX2022001027A (enExample)
WO (1) WO2021020845A1 (enExample)
ZA (1) ZA202200905B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021008870A2 (pt) 2019-08-12 2021-11-30 Abl Bio Inc Anticorpo, um ou mais polinucleotídeos, composição, uso do anticorpo, e, método para tratar câncer.
WO2023083381A1 (zh) 2021-11-15 2023-05-19 成都百利多特生物药业有限责任公司 双特异性抗体-喜树碱类药物偶联物及其医药用途
CN118369340A (zh) * 2021-11-25 2024-07-19 盛禾(中国)生物制药有限公司 一种双特异性抗原结合蛋白
JP2025512915A (ja) * 2022-04-07 2025-04-22 ユハン コーポレーション Her2の発現レベルが低いがんを治療又は予防するための薬学的組成物
EP4644417A4 (en) * 2022-12-30 2026-02-11 Abclon Inc AFFICORPS SPECIFICALLY BINDING TO CD137 AND ITS USE
KR20240164748A (ko) * 2023-05-12 2024-11-20 앱클론(주) 항체 또는 그의 항원 결합 단편, 및 어피바디를 포함하는 이중 항원 표적 단백질 복합체
KR102927129B1 (ko) 2025-03-18 2026-02-11 이트너스 주식회사 임직원 공간 산정을 위한 사무 및 부대 시설 면적 계산 솔루션

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0766745T3 (da) 1995-04-08 2002-11-25 Lg Chemical Ltd Monoklonalt antistof, som er specifikt for humant 4-1BB samt cellelinje, som producerer dette
US7288638B2 (en) 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
PL1871805T3 (pl) 2005-02-07 2020-03-31 Roche Glycart Ag Cząsteczki wiążące antygen, które wiążą egfr, wektory kodujące te cząsteczki oraz ich zastosowania
EP3539981A1 (en) * 2006-09-10 2019-09-18 Glycotope GmbH Use of human cells of myeloid leukaemia origin for expression of antibodies
DK2699598T3 (en) * 2011-04-19 2019-04-23 Pfizer COMBINATIONS OF ANTI-4-1BB ANTIBODIES AND ADCC-INducing ANTIBODIES FOR TREATMENT OF CANCER
SG11201601542SA (en) * 2013-08-16 2016-04-28 Sloan Kettering Inst Cancer Selective grp94 inhibitors and uses thereof
CA3138083A1 (en) * 2014-12-22 2016-06-30 Systimmune, Inc. Bispecific tetravalent antibodies and methods of making and using thereof
EP3356401B1 (en) * 2015-09-30 2020-06-24 IGM Biosciences, Inc. Binding molecules with modified j-chain
JP2019513373A (ja) 2016-03-31 2019-05-30 ネオン セラピューティクス, インコーポレイテッド ネオ抗原およびその使用方法
EP3445788B1 (en) * 2016-04-22 2022-01-19 Alligator Bioscience AB Novel bispecific polypeptides against cd137
KR102702926B1 (ko) 2017-04-13 2024-09-06 사이로파 비.브이. 항-sirp 알파 항체
EP3655439A1 (en) * 2017-07-20 2020-05-27 Aptevo Research and Development LLC Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
CN111819198A (zh) * 2017-12-28 2020-10-23 尤利乌斯·马克西米利安维尔茨堡大学 具有非FcγR依赖性激动活性的肿瘤坏死因子(TNF)受体超家族(TNFRSF)受体-激活抗体融合蛋白(具有非FcγR依赖性激动活性的TNFRSF受体-激活抗体融合蛋白;TRAAFFIAA)
JP7575100B2 (ja) * 2018-11-13 2024-10-29 ジェイエヌ バイオサイエンシーズ エルエルシー 免疫細胞活性化のための二重特異性抗体
CN113286825B (zh) * 2018-11-30 2024-06-18 爱必乐生物公司 抗pd-l1/抗4-1bb双特异性抗体及其用途
BR112021008870A2 (pt) * 2019-08-12 2021-11-30 Abl Bio Inc Anticorpo, um ou mais polinucleotídeos, composição, uso do anticorpo, e, método para tratar câncer.
JP7702961B6 (ja) * 2020-02-28 2025-07-17 上海復宏漢霖生物技術股▲フン▼有限公司 抗cd137コンストラクト、多重特異性抗体及びその使用

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