JP2022541793A5 - - Google Patents
Info
- Publication number
- JP2022541793A5 JP2022541793A5 JP2022503802A JP2022503802A JP2022541793A5 JP 2022541793 A5 JP2022541793 A5 JP 2022541793A5 JP 2022503802 A JP2022503802 A JP 2022503802A JP 2022503802 A JP2022503802 A JP 2022503802A JP 2022541793 A5 JP2022541793 A5 JP 2022541793A5
- Authority
- JP
- Japan
- Prior art keywords
- raav
- raav vector
- seq
- gene
- vector according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962876540P | 2019-07-19 | 2019-07-19 | |
| US62/876,540 | 2019-07-19 | ||
| PCT/US2020/042663 WO2021016126A1 (en) | 2019-07-19 | 2020-07-17 | Aav cardiac gene therapy for cardiomyopathy in humans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022541793A JP2022541793A (ja) | 2022-09-27 |
| JP2022541793A5 true JP2022541793A5 (enExample) | 2023-07-26 |
Family
ID=74193792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503802A Pending JP2022541793A (ja) | 2019-07-19 | 2020-07-17 | ヒトにおける心筋症のためのａａｖ心臓遺伝子治療 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20220265858A1 (enExample) |
| EP (1) | EP3999074A4 (enExample) |
| JP (1) | JP2022541793A (enExample) |
| KR (1) | KR20220034801A (enExample) |
| CN (1) | CN114206351A (enExample) |
| AR (1) | AR122289A1 (enExample) |
| AU (1) | AU2020316339A1 (enExample) |
| BR (1) | BR112022000898A2 (enExample) |
| CA (1) | CA3142534A1 (enExample) |
| CL (1) | CL2022000115A1 (enExample) |
| CO (1) | CO2022001686A2 (enExample) |
| IL (1) | IL289667A (enExample) |
| MX (1) | MX2022000767A (enExample) |
| SG (1) | SG11202112140SA (enExample) |
| TW (1) | TW202117017A (enExample) |
| WO (1) | WO2021016126A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116867512A (zh) * | 2020-12-23 | 2023-10-10 | 佛罗里达州大学研究基金会 | 包装效率提高的用于心脏基因治疗的载体 |
| CN119317718A (zh) | 2022-01-25 | 2025-01-14 | 宾夕法尼亚州大学信托人 | 用于改善心脏转导和肝脏去靶向的aav衣壳 |
| EP4634394A2 (en) | 2022-12-17 | 2025-10-22 | The Trustees of The University of Pennsylvania | Recombinant aav mutant vectors with cardiac and skeletal muscle-specific targeting motifs and compositions containing same |
| WO2024130070A2 (en) | 2022-12-17 | 2024-06-20 | The Trustees Of The University Of Pennsylvania | Recombinant aav capsids with cardiac- and skeletal muscle- specific targeting motifs and uses thereof |
| WO2025007046A1 (en) | 2023-06-29 | 2025-01-02 | The Trustees Of The University Of Pennsylvania | Mutant aav with central nervous system targeting motifs and compositions containing same |
| KR20260114566A (ko) | 2023-11-14 | 2026-07-22 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 심근 및 골격근-특이적 표적화 모티프를 갖는 조성물 및 이의 용도 |
| WO2026132516A1 (en) * | 2024-12-20 | 2026-06-25 | Patrick Most | S100a1 protein-derived peptide for use in treating cancer or in treating or preventing antineoplastic agent-mediated cytotoxicity, cancer therapy-related cardiac dysfunction or cancer therapy related heart failure |
| CN121674484A (zh) * | 2025-11-14 | 2026-03-17 | 广州派真生物技术有限公司 | 一种高产细胞毒性基因的rAAV质粒系统及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19915485A1 (de) * | 1999-04-07 | 2000-10-19 | Hugo A Katus | Therapie der Herzinsuffizienz |
| CA2412847A1 (en) * | 2000-06-30 | 2002-01-10 | Collateral Therapeutics, Inc. | Dual recombinant gene therapy compositions and methods of use |
| WO2008054713A2 (en) * | 2006-10-30 | 2008-05-08 | Thomas Jefferson University | Tissue specific gene therapy treatment |
| EP2295072A1 (en) * | 2009-09-15 | 2011-03-16 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Use of ARC for inhibiting cell death during liver failure |
| EP3052118A1 (en) * | 2013-10-01 | 2016-08-10 | Ruprecht-Karls-Universität Heidelberg | S100 based treatment of cardiac power failure |
| WO2017191274A2 (en) * | 2016-05-04 | 2017-11-09 | Curevac Ag | Rna encoding a therapeutic protein |
| US20200308582A1 (en) * | 2017-10-12 | 2020-10-01 | Universität Heidelberg | Kcnk3-based gene therapy of cardiac arrhythmia |
| CN112272705A (zh) * | 2018-06-08 | 2021-01-26 | 佛罗里达大学研究基金会有限公司 | 用于心肌病的aav心脏基因治疗 |
-
2020
- 2020-07-17 BR BR112022000898A patent/BR112022000898A2/pt unknown
- 2020-07-17 JP JP2022503802A patent/JP2022541793A/ja active Pending
- 2020-07-17 MX MX2022000767A patent/MX2022000767A/es unknown
- 2020-07-17 TW TW109124287A patent/TW202117017A/zh unknown
- 2020-07-17 AU AU2020316339A patent/AU2020316339A1/en not_active Abandoned
- 2020-07-17 EP EP20844818.3A patent/EP3999074A4/en active Pending
- 2020-07-17 AR ARP200102021A patent/AR122289A1/es not_active Application Discontinuation
- 2020-07-17 CN CN202080052456.6A patent/CN114206351A/zh active Pending
- 2020-07-17 US US17/628,139 patent/US20220265858A1/en active Pending
- 2020-07-17 WO PCT/US2020/042663 patent/WO2021016126A1/en not_active Ceased
- 2020-07-17 CA CA3142534A patent/CA3142534A1/en active Pending
- 2020-07-17 KR KR1020227002673A patent/KR20220034801A/ko not_active Ceased
- 2020-07-17 SG SG11202112140SA patent/SG11202112140SA/en unknown
-
2022
- 2022-01-06 IL IL289667A patent/IL289667A/en unknown
- 2022-01-17 CL CL2022000115A patent/CL2022000115A1/es unknown
- 2022-02-17 CO CONC2022/0001686A patent/CO2022001686A2/es unknown
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