JP2022540716A - プローブの組合せを用いたゲノム配列の検出、プローブ分子、および生物の特異的検出用のプローブを含むアレイ - Google Patents

プローブの組合せを用いたゲノム配列の検出、プローブ分子、および生物の特異的検出用のプローブを含むアレイ Download PDF

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JP2022540716A
JP2022540716A JP2022503578A JP2022503578A JP2022540716A JP 2022540716 A JP2022540716 A JP 2022540716A JP 2022503578 A JP2022503578 A JP 2022503578A JP 2022503578 A JP2022503578 A JP 2022503578A JP 2022540716 A JP2022540716 A JP 2022540716A
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probe
genome
amplicon
virtual
nucleotide sequence
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クラップロート ホルガー
ベトナー ソーニャ
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Safeguard Biosystems Holdings Ltd
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/10—Detection mode being characterised by the assay principle
    • C12Q2565/102—Multiple non-interacting labels
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/501—Detection characterised by immobilisation to a surface being an array of oligonucleotides
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2022503578A 2019-07-19 2020-07-17 プローブの組合せを用いたゲノム配列の検出、プローブ分子、および生物の特異的検出用のプローブを含むアレイ Pending JP2022540716A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962876413P 2019-07-19 2019-07-19
US62/876,413 2019-07-19
US202063004664P 2020-04-03 2020-04-03
US63/004,664 2020-04-03
PCT/EP2020/070308 WO2021013736A1 (en) 2019-07-19 2020-07-17 Detection of genomic sequences using combinations of probes, probe molecules and arrays comprising the probes for the specific detection of organisms

Publications (2)

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JP2022540716A true JP2022540716A (ja) 2022-09-16
JP2022540716A5 JP2022540716A5 (https=) 2023-07-18

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JP2022503578A Pending JP2022540716A (ja) 2019-07-19 2020-07-17 プローブの組合せを用いたゲノム配列の検出、プローブ分子、および生物の特異的検出用のプローブを含むアレイ

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US (1) US20220267833A1 (https=)
EP (1) EP3999658A1 (https=)
JP (1) JP2022540716A (https=)
KR (1) KR20220035482A (https=)
CN (1) CN114269944A (https=)
AU (1) AU2020317617A1 (https=)
BR (1) BR112021026672A2 (https=)
CA (1) CA3147364A1 (https=)
IL (1) IL289760A (https=)
MX (1) MX2022000628A (https=)
PH (1) PH12022550137A1 (https=)
TW (1) TW202117021A (https=)
WO (1) WO2021013736A1 (https=)
ZA (1) ZA202200284B (https=)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
US11562057B2 (en) 2020-02-05 2023-01-24 Quantum Digital Solutions Corporation Ecosystem security platforms for enabling data exchange between members of a digital ecosystem using digital genomic data sets
EP4679262A3 (en) 2021-02-04 2026-04-01 Quantum Digital Solutions Corporation Cyphergenics-based ecosystem security platforms
WO2022169969A1 (en) * 2021-02-04 2022-08-11 Quantum Digital Solutions Corporation Cyphergenics-based ecosystem security platforms
WO2024172833A2 (en) 2022-08-03 2024-08-22 Quantum Digital Solutions Corporation Cyphergenics-enabled digital ecosystems and cyphergenics-enabled digital signatures
WO2026006533A1 (en) 2024-06-26 2026-01-02 Quantum Digital Solutions Corporation Collusion-resistant identity-based and quantum-resilient secure correlation schemes

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228718A1 (en) * 2005-04-11 2006-10-12 National Cheng Kung University Method for rapidly identifying bacteria and kit thereof
JP2010532665A (ja) * 2007-07-11 2010-10-14 ユニヴェルシテ ラヴァル 細菌性および真菌性敗血症の病原菌の高感度な増幅および検出用の核酸配列およびその組合せ

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066584A (en) 1988-09-23 1991-11-19 Cetus Corporation Methods for generating single stranded dna by the polymerase chain reaction
US6638719B1 (en) * 1999-07-14 2003-10-28 Affymetrix, Inc. Genotyping biallelic markers
US20030134293A1 (en) * 1999-11-16 2003-07-17 Zhiping Liu Method for rapid and accurate identification of microorganisms
US7205104B2 (en) * 2000-03-24 2007-04-17 Eppendorf Array Technologies Sa (Eat) Identification of biological (micro) organisms by detection of their homologous nucleotide sequences on arrays
CN1280422C (zh) 2004-08-26 2006-10-18 北京博奥生物芯片有限责任公司 一种不对称pcr扩增方法及其应用
EP3181700A1 (en) 2015-12-18 2017-06-21 Safeguard Biosystems Holdings Ltd. Three-dimensional polymer networks with channels situated therein
EP3199629A1 (en) 2016-01-30 2017-08-02 Safeguard Biosystems Holdings Ltd. Bead beating tube and method for extracting deoxyribonucleic acid and/or ribonucleic acid from microorganisms
EP3418741A1 (en) 2017-06-19 2018-12-26 Safeguard Biosystems Holdings Ltd. Three-dimensional polymer networks and their use
US10513730B2 (en) 2017-11-22 2019-12-24 Safeguard Biosystems Holdings Ltd. Asymmetric PCR methods, primers and kits

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228718A1 (en) * 2005-04-11 2006-10-12 National Cheng Kung University Method for rapidly identifying bacteria and kit thereof
JP2010532665A (ja) * 2007-07-11 2010-10-14 ユニヴェルシテ ラヴァル 細菌性および真菌性敗血症の病原菌の高感度な増幅および検出用の核酸配列およびその組合せ

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF CLINICAL MICROBIOLOGY, vol. 2005,Vol.43, No.4, pp.1515-1521, JPN6024023117, ISSN: 0005534537 *

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Publication number Publication date
TW202117021A (zh) 2021-05-01
EP3999658A1 (en) 2022-05-25
WO2021013736A1 (en) 2021-01-28
US20220267833A1 (en) 2022-08-25
AU2020317617A1 (en) 2022-03-03
CN114269944A (zh) 2022-04-01
IL289760A (en) 2022-03-01
PH12022550137A1 (en) 2024-02-12
ZA202200284B (en) 2022-09-28
MX2022000628A (es) 2022-03-11
BR112021026672A2 (pt) 2022-02-15
CA3147364A1 (en) 2021-01-28
KR20220035482A (ko) 2022-03-22

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