JP2022540678A5 - - Google Patents
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- Publication number
- JP2022540678A5 JP2022540678A5 JP2022502486A JP2022502486A JP2022540678A5 JP 2022540678 A5 JP2022540678 A5 JP 2022540678A5 JP 2022502486 A JP2022502486 A JP 2022502486A JP 2022502486 A JP2022502486 A JP 2022502486A JP 2022540678 A5 JP2022540678 A5 JP 2022540678A5
- Authority
- JP
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025113468A JP2025148397A (ja) | 2019-07-16 | 2025-07-04 | （ｒ）－４－（１－（（３－（ジフルオロメチル）－１－メチル－１ｈ－ピラゾール－４－イル）スルホニル）－１－フルオロエチル）－ｎ－（イソキサゾール－３－イル）ピペリジン－１－カルボキシアミドの多形体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962874855P | 2019-07-16 | 2019-07-16 | |
| US62/874,855 | 2019-07-16 | ||
| PCT/US2020/042028 WO2021011586A1 (en) | 2019-07-16 | 2020-07-15 | Polymorphic forms of (r)-4-(1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-(isoxazol-3-yl)piperidine-1-carboxamide |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025113468A Division JP2025148397A (ja) | 2019-07-16 | 2025-07-04 | （ｒ）－４－（１－（（３－（ジフルオロメチル）－１－メチル－１ｈ－ピラゾール－４－イル）スルホニル）－１－フルオロエチル）－ｎ－（イソキサゾール－３－イル）ピペリジン－１－カルボキシアミドの多形体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022540678A JP2022540678A (ja) | 2022-09-16 |
| JP2022540678A5 true JP2022540678A5 (https=) | 2023-08-02 |
| JPWO2021011586A5 JPWO2021011586A5 (https=) | 2023-08-02 |
Family
ID=71895284
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502486A Pending JP2022540678A (ja) | 2019-07-16 | 2020-07-15 | （ｒ）－４－（１－（（３－（ジフルオロメチル）－１－メチル－１ｈ－ピラゾール－４－イル）スルホニル）－１－フルオロエチル）－ｎ－（イソキサゾール－３－イル）ピペリジン－１－カルボキシアミドの多形体 |
| JP2025113468A Pending JP2025148397A (ja) | 2019-07-16 | 2025-07-04 | （ｒ）－４－（１－（（３－（ジフルオロメチル）－１－メチル－１ｈ－ピラゾール－４－イル）スルホニル）－１－フルオロエチル）－ｎ－（イソキサゾール－３－イル）ピペリジン－１－カルボキシアミドの多形体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025113468A Pending JP2025148397A (ja) | 2019-07-16 | 2025-07-04 | （ｒ）－４－（１－（（３－（ジフルオロメチル）－１－メチル－１ｈ－ピラゾール－４－イル）スルホニル）－１－フルオロエチル）－ｎ－（イソキサゾール－３－イル）ピペリジン－１－カルボキシアミドの多形体 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20210053939A1 (https=) |
| EP (1) | EP3999504A1 (https=) |
| JP (2) | JP2022540678A (https=) |
| KR (1) | KR20220035176A (https=) |
| CN (1) | CN114127061A (https=) |
| AU (1) | AU2020315605A1 (https=) |
| BR (1) | BR112022000474A2 (https=) |
| CA (1) | CA3143965A1 (https=) |
| CL (1) | CL2022000050A1 (https=) |
| CO (1) | CO2022000117A2 (https=) |
| IL (1) | IL289817A (https=) |
| MX (1) | MX2022000606A (https=) |
| PE (1) | PE20220645A1 (https=) |
| WO (1) | WO2021011586A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116082326B (zh) * | 2022-12-16 | 2024-12-27 | 药康众拓(江苏)医药科技有限公司北京分公司 | 一种氘代吡唑磺酰甲基-哌啶异噁唑脲类化合物及其用途 |
| CN117865941B (zh) * | 2024-03-13 | 2024-06-28 | 上海方予健康医药科技有限公司 | 取代哌啶化合物及其制备方法和应用 |
| WO2025244956A1 (en) | 2024-05-20 | 2025-11-27 | MyoKardia, Inc. | Methods of manufacturing danicamtiv |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0007784A (pt) | 1999-01-27 | 2002-02-05 | American Cyanamid Co | Composto, método para inibir mudanças patológicas mediadas pela enzima que converte o tnf-alfa (tace) em um mamìfero, composição farmacêutica, e, processo para preparar um composto |
| WO2005117882A2 (en) | 2004-04-20 | 2005-12-15 | Incyte Corporation | Hydroxamic acid derivatives as metalloprotease inhibitors |
| JP5080970B2 (ja) | 2004-06-17 | 2012-11-21 | サイトキネティクス・インコーポレーテッド | 心疾患を治療するための置換尿素誘導体 |
| AR055831A1 (es) | 2004-12-30 | 2007-09-12 | Janssen Pharmaceutica Nv | Pepirazinilureas y piperidinilureas como moduladores de hidrolasa de amida de acidos grasos |
| KR100979577B1 (ko) | 2005-03-03 | 2010-09-01 | 에프. 호프만-라 로슈 아게 | 2형 진성 당뇨병의 치료를 위한11-베타-하이드록시스테로이드 탈수소효소의 억제제로서1-설폰일-피페리딘-3-카복실산 아마이드 유도체 |
| WO2008120759A1 (ja) | 2007-03-30 | 2008-10-09 | Japan Tobacco Inc. | ウレア化合物およびその用途 |
| US8461209B2 (en) | 2007-06-20 | 2013-06-11 | Mitsubishi Tanabe Pharma Corporation | Malonic acid sulfonamide derivative and pharmaceutical use thereof |
| US20090069288A1 (en) | 2007-07-16 | 2009-03-12 | Breinlinger Eric C | Novel therapeutic compounds |
| RU2443699C2 (ru) | 2007-09-20 | 2012-02-27 | Айрм Ллк | Соединения и композиции в качестве модуляторов активности gpr119 |
| CN101801952A (zh) | 2007-10-01 | 2010-08-11 | 弗·哈夫曼-拉罗切有限公司 | 用作ccr受体拮抗剂的n-杂环联芳基甲酰胺类化合物 |
| MX2010003868A (es) | 2007-10-09 | 2010-04-27 | Hoffmann La Roche | Cis-imidazolinas quirales. |
| CN102123990B (zh) | 2008-06-19 | 2014-07-09 | 武田药品工业株式会社 | 杂环化合物及其用途 |
| US8324178B2 (en) | 2008-10-31 | 2012-12-04 | The Regents Of The University Of California | Method of treatment using alpha-1-adrenergic agonist compounds |
| WO2010113377A1 (ja) | 2009-04-01 | 2010-10-07 | パナソニック株式会社 | デジタル周波数／位相ロックドループ |
| CN102596949B (zh) | 2009-11-11 | 2015-08-19 | 大日本住友制药株式会社 | 8-氮杂双环[3.2.1]辛烷-8-甲酰胺衍生物 |
| WO2015005305A1 (ja) | 2013-07-09 | 2015-01-15 | 小野薬品工業株式会社 | Ａｌｘｒ作動化合物 |
| NZ717552A (en) | 2013-08-07 | 2021-07-30 | Merck Patent Gmbh | Piperidine urea derivatives |
| PL3636649T3 (pl) | 2014-01-24 | 2024-05-06 | Turning Point Therapeutics, Inc. | Diaryle makrocykliczne jako modulatory kinaz białkowych |
| IL295547A (en) | 2015-01-22 | 2022-10-01 | Myokardia Inc | Piperidine-4-methylsulfonyl-modified urea compounds for the treatment of dilated cardiomyopathy (dcm) |
| WO2020236736A1 (en) | 2019-05-19 | 2020-11-26 | MyoKardia, Inc. | Treatment of systolic dysfunction and heart failure with reduced ejection fraction with the compound(r)-4-(1-((3-(difluoromethyl)-1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-(isoxazol-3-yl)piperidine-1-carboxamide |
-
2020
- 2020-07-15 EP EP20750115.6A patent/EP3999504A1/en active Pending
- 2020-07-15 AU AU2020315605A patent/AU2020315605A1/en active Pending
- 2020-07-15 KR KR1020227004725A patent/KR20220035176A/ko active Pending
- 2020-07-15 JP JP2022502486A patent/JP2022540678A/ja active Pending
- 2020-07-15 PE PE2022000049A patent/PE20220645A1/es unknown
- 2020-07-15 MX MX2022000606A patent/MX2022000606A/es unknown
- 2020-07-15 US US16/929,230 patent/US20210053939A1/en not_active Abandoned
- 2020-07-15 CN CN202080051794.8A patent/CN114127061A/zh active Pending
- 2020-07-15 CA CA3143965A patent/CA3143965A1/en active Pending
- 2020-07-15 WO PCT/US2020/042028 patent/WO2021011586A1/en not_active Ceased
- 2020-07-15 BR BR112022000474A patent/BR112022000474A2/pt unknown
-
2022
- 2022-01-10 CL CL2022000050A patent/CL2022000050A1/es unknown
- 2022-01-12 CO CONC2022/0000117A patent/CO2022000117A2/es unknown
- 2022-01-12 IL IL289817A patent/IL289817A/en unknown
- 2022-02-23 US US17/678,569 patent/US12459919B2/en active Active
-
2025
- 2025-07-04 JP JP2025113468A patent/JP2025148397A/ja active Pending