JP2022540318A5 - - Google Patents
Info
- Publication number
- JP2022540318A5 JP2022540318A5 JP2021574234A JP2021574234A JP2022540318A5 JP 2022540318 A5 JP2022540318 A5 JP 2022540318A5 JP 2021574234 A JP2021574234 A JP 2021574234A JP 2021574234 A JP2021574234 A JP 2021574234A JP 2022540318 A5 JP2022540318 A5 JP 2022540318A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- nucleic acid
- sequence
- dna
- acid construct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860186P | 2019-06-11 | 2019-06-11 | |
| US62/860,186 | 2019-06-11 | ||
| PCT/IB2020/055507 WO2020250181A1 (en) | 2019-06-11 | 2020-06-11 | Targeted gene editing constructs and methods of using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022540318A JP2022540318A (ja) | 2022-09-15 |
| JP2022540318A5 true JP2022540318A5 (https=) | 2023-07-19 |
| JP7830129B2 JP7830129B2 (ja) | 2026-03-16 |
Family
ID=72178837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021574234A Active JP7830129B2 (ja) | 2019-06-11 | 2020-06-11 | 標的遺伝子編集構築物およびそれを使用する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220235379A1 (https=) |
| EP (1) | EP3983541A1 (https=) |
| JP (1) | JP7830129B2 (https=) |
| KR (1) | KR20220019794A (https=) |
| CN (1) | CN114026240A (https=) |
| AU (1) | AU2020290790B2 (https=) |
| BR (1) | BR112021024828A2 (https=) |
| CA (1) | CA3141422A1 (https=) |
| IL (1) | IL288794A (https=) |
| MX (1) | MX2021015157A (https=) |
| WO (1) | WO2020250181A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7419168B2 (ja) * | 2020-06-10 | 2024-01-22 | 株式会社東芝 | 改変型ｐｉｇｇｙＢａｃトランスポゼースのポリペプチド、それをコードするポリヌクレオチド、導入キャリア、キット、細胞のゲノムに目的配列を組込む方法及び細胞製造方法 |
| AU2021403660A1 (en) | 2020-12-16 | 2023-07-06 | Universitat Pompeu Fabra | Programmable transposases and uses thereof |
| JP2023553701A (ja) * | 2020-12-16 | 2023-12-25 | ウニベルシタット ポンペウ ファブラ | 先天性筋ジストロフィーの処置のための治療用ｌａｍａ２ペイロード |
| EP4341392A4 (en) * | 2021-05-14 | 2025-02-19 | Becton Dickinson and Company | Multiplexed unbiased nucleic acid amplification method |
| CA3234642A1 (en) * | 2021-10-04 | 2023-04-13 | Poseida Therapeutics, Inc. | Transposases and uses thereof |
| JP2024545923A (ja) * | 2021-12-30 | 2024-12-13 | リーゲル セラピューティクス，インコーポレイティッド | ナトリウム電位依存性チャネルアルファサブユニット１の発現を調節するための組成物、及びその使用 |
| WO2023141504A2 (en) * | 2022-01-19 | 2023-07-27 | Genomeminer, Inc. (Formally Tupac Bio, Inc.) | Dcas9-integrase for targeted genome editing |
| KR20230122932A (ko) | 2022-02-15 | 2023-08-22 | 주식회사 엘지에너지솔루션 | 이차전지 제조장치 및 이를 이용하는 이차전지 제조방법 |
| CN116218904B (zh) * | 2022-11-03 | 2025-04-15 | 国药中生生物技术研究院有限公司 | 一种可提高工程化细胞外泌体中特定核酸分子载量的方法及其应用 |
| CN118185901B (zh) * | 2022-12-12 | 2025-03-21 | 北京精缮生物科技有限责任公司 | 一种PBase蛋白、融合蛋白、核酸和基因整合系统及应用 |
| JP2026511237A (ja) * | 2023-03-27 | 2026-04-10 | ベイジン・アストラジェノミクス・テクノロジー・カンパニー，リミテッド | 単離されたトランスポザーゼ及びその使用 |
| CN121712899A (zh) * | 2023-04-27 | 2026-03-20 | 伦斯勒理工学院 | 用于在真核细胞中准确插入dna序列的重组酶 |
| CN121443733A (zh) | 2023-06-01 | 2026-01-30 | 英特格拉治疗公司 | 转座酶及其用途 |
| WO2025212757A2 (en) * | 2024-04-03 | 2025-10-09 | Buck Institute For Research On Aging | Cas enabled targeted transposition |
| CN119842638A (zh) * | 2025-01-20 | 2025-04-18 | 天津大学 | 融合酶突变体及其在氟代白藜芦醇合成中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60335637D1 (de) * | 2002-07-24 | 2011-02-17 | Manoa Biosciences Inc | Vektoren auf transposonbasis und verfahren zur integration von nukleinsäuren |
| WO2013012824A2 (en) * | 2011-07-15 | 2013-01-24 | The Johns Hopkins University | Trichoplusia ni piggybac transposases with reduced integration activity |
| US20170114333A1 (en) * | 2014-04-11 | 2017-04-27 | The Johns Hopkins University | Improvements to eukaryotic transposase mutants and transposon end compositions for modifying nucleic acids and methods for production and use in the generation of sequencing libraries |
| JP2018513681A (ja) * | 2015-03-31 | 2018-05-31 | エクセリゲン サイエンティフィック, インコーポレイテッドExeligen Scientific, Inc. | 細胞または生物のゲノムへのＤＮＡ配列の標的化組み込みのためのＣａｓ９レトロウイルスインテグラーゼおよびＣａｓ９レコンビナーゼ系 |
| KR102249982B1 (ko) * | 2015-12-14 | 2021-05-11 | 게놈프론티어 테라퓨틱스 인코포레이티드 | 트랜스포존 시스템, 이를 포함한 키트, 및 이들의 용도 |
| WO2018175872A1 (en) * | 2017-03-24 | 2018-09-27 | President And Fellows Of Harvard College | Methods of genome engineering by nuclease-transposase fusion proteins |
-
2020
- 2020-06-11 US US17/617,252 patent/US20220235379A1/en active Pending
- 2020-06-11 KR KR1020227000857A patent/KR20220019794A/ko active Pending
- 2020-06-11 JP JP2021574234A patent/JP7830129B2/ja active Active
- 2020-06-11 BR BR112021024828A patent/BR112021024828A2/pt unknown
- 2020-06-11 CN CN202080043025.3A patent/CN114026240A/zh active Pending
- 2020-06-11 AU AU2020290790A patent/AU2020290790B2/en active Active
- 2020-06-11 MX MX2021015157A patent/MX2021015157A/es unknown
- 2020-06-11 EP EP20760532.0A patent/EP3983541A1/en active Pending
- 2020-06-11 WO PCT/IB2020/055507 patent/WO2020250181A1/en not_active Ceased
- 2020-06-11 CA CA3141422A patent/CA3141422A1/en active Pending
-
2021
- 2021-12-08 IL IL288794A patent/IL288794A/en unknown
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