JP2022533983A5 - - Google Patents
Info
- Publication number
- JP2022533983A5 JP2022533983A5 JP2021568813A JP2021568813A JP2022533983A5 JP 2022533983 A5 JP2022533983 A5 JP 2022533983A5 JP 2021568813 A JP2021568813 A JP 2021568813A JP 2021568813 A JP2021568813 A JP 2021568813A JP 2022533983 A5 JP2022533983 A5 JP 2022533983A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- gene therapy
- delivery
- composition according
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962849794P | 2019-05-17 | 2019-05-17 | |
| US62/849,794 | 2019-05-17 | ||
| PCT/US2020/028352 WO2020236352A1 (en) | 2019-05-17 | 2020-04-15 | Optimized gene therapy targeting retinal cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022533983A JP2022533983A (ja) | 2022-07-27 |
| JP2022533983A5 true JP2022533983A5 (enExample) | 2023-04-25 |
| JP7707081B2 JP7707081B2 (ja) | 2025-07-14 |
Family
ID=70482910
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568543A Pending JP2022533645A (ja) | 2019-05-17 | 2020-04-15 | グリコシドヒドロラーゼ酵素を使用する網膜細胞への遺伝子治療ベクターの送達の改善 |
| JP2021568813A Active JP7707081B2 (ja) | 2019-05-17 | 2020-04-15 | 網膜細胞を標的とした最適化された遺伝子治療 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568543A Pending JP2022533645A (ja) | 2019-05-17 | 2020-04-15 | グリコシドヒドロラーゼ酵素を使用する網膜細胞への遺伝子治療ベクターの送達の改善 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20220233655A1 (enExample) |
| EP (2) | EP3969060A1 (enExample) |
| JP (2) | JP2022533645A (enExample) |
| KR (1) | KR20220009427A (enExample) |
| CN (1) | CN114126667A (enExample) |
| AR (1) | AR118696A1 (enExample) |
| AU (2) | AU2020278960A1 (enExample) |
| CA (2) | CA3141017A1 (enExample) |
| TW (1) | TW202110486A (enExample) |
| WO (2) | WO2020236351A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20260045918A (ko) * | 2019-12-25 | 2026-04-03 | 루머스 리미티드 | 도광 광학 엘리먼트와 연관된 광학 배열체를 사용하여 눈으로부터 광을 방향 전환시키는 것에 기초한 시선 추적을 위한 광학계 및 방법 |
| CN114516901B (zh) * | 2022-03-11 | 2023-01-17 | 上海勉亦生物科技有限公司 | 一种神经系统高亲和性的aav载体及其应用 |
| CN115323001B (zh) * | 2022-07-28 | 2024-11-26 | 深圳先进技术研究院 | 一种靶向视网膜的基因递送系统及其应用 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| PT728214E (pt) | 1993-11-09 | 2004-11-30 | Ohio Med College | Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado |
| WO1995013365A1 (en) | 1993-11-09 | 1995-05-18 | Targeted Genetics Corporation | Generation of high titers of recombinant aav vectors |
| US5658785A (en) | 1994-06-06 | 1997-08-19 | Children's Hospital, Inc. | Adeno-associated virus materials and methods |
| US5856152A (en) | 1994-10-28 | 1999-01-05 | The Trustees Of The University Of Pennsylvania | Hybrid adenovirus-AAV vector and methods of use therefor |
| CA2207927A1 (en) | 1994-12-06 | 1996-06-13 | Targeted Genetics Corporation | Packaging cell lines for generation of high titers of recombinant aav vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| WO1997008298A1 (en) | 1995-08-30 | 1997-03-06 | Genzyme Corporation | Chromatographic purification of adenovirus and aav |
| US6632670B1 (en) | 1995-09-08 | 2003-10-14 | Genzyme Corporation | AAV vectors for gene therapy |
| US5910434A (en) | 1995-12-15 | 1999-06-08 | Systemix, Inc. | Method for obtaining retroviral packaging cell lines producing high transducing efficiency retroviral supernatant |
| JP2001500497A (ja) | 1996-09-06 | 2001-01-16 | トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 組換えアデノ随伴ウイルスに指図される遺伝子治療の方法 |
| DK1009808T3 (da) | 1997-09-05 | 2013-01-21 | Genzyme Corp | Fremgangsmåder til generering af hjælper-frie præparater af rekombinante aav-vektorer med høj titer |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6258595B1 (en) | 1999-03-18 | 2001-07-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for helper-free production of recombinant adeno-associated viruses |
| US7056502B2 (en) | 2000-04-28 | 2006-06-06 | The Trustees Of The University Of Pennsylvania | Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids |
| US9233131B2 (en) | 2003-06-30 | 2016-01-12 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| US9441244B2 (en) | 2003-06-30 | 2016-09-13 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| WO2012109214A1 (en) * | 2011-02-07 | 2012-08-16 | The University Of North Carolina At Chapel Hill | Targeted transduction of aav vectors |
| TR201908020T4 (tr) * | 2011-02-17 | 2019-06-21 | Univ Pennsylvania | Doku özgüllüğünü değiştirmek ve aav9-aracılı gen transferini geliştirmek için bileşimler ve yöntemler. |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| DE102012007232B4 (de) | 2012-04-07 | 2014-03-13 | Susanne Weller | Verfahren zur Herstellung von rotierenden elektrischen Maschinen |
| AU2013296425B2 (en) | 2012-08-01 | 2018-06-07 | Nationwide Children's Hospital | Intrathecal delivery of recombinant adeno-associated virus 9 |
| EP2968476B1 (en) * | 2013-03-14 | 2021-05-05 | Wayne State University | A plasmin for use in enhancing delivery of therapeutic compounds to the eyes or for improving vision |
| JP2015092462A (ja) | 2013-09-30 | 2015-05-14 | Tdk株式会社 | 正極及びそれを用いたリチウムイオン二次電池 |
| US20170007720A1 (en) * | 2014-02-21 | 2017-01-12 | University Of Florida Research Foundation, Inc. | Methods and compositions for gene delivery to on bipolar cells |
| GB201403260D0 (en) * | 2014-02-25 | 2014-04-09 | Univ Manchester | Treatment of retinal degeneration using gene therapy |
| WO2015141521A1 (ja) | 2014-03-21 | 2015-09-24 | 株式会社日立国際電気 | 基板処理装置、半導体装置の製造方法及び記録媒体 |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| JP6197169B2 (ja) | 2014-09-29 | 2017-09-20 | 東芝メモリ株式会社 | 半導体装置の製造方法 |
| WO2016100575A1 (en) * | 2014-12-16 | 2016-06-23 | Board Of Regents Of The University Of Nebraska | Gene therapy for juvenile batten disease |
| JP6684343B2 (ja) * | 2015-05-21 | 2020-04-22 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | ニューロン生存因子の相乗組み合わせ及びその使用 |
| CN108603235A (zh) | 2015-07-30 | 2018-09-28 | 马萨诸塞眼科耳科诊所 | 祖先病毒序列及其用途 |
| KR102738860B1 (ko) | 2015-10-23 | 2024-12-04 | 유니버시티 오브 아이오와 리써치 파운데이션 | 리소좀 축적 질환 (lsd)을 갖는 포유동물의 치료 방법에 사용하기 위한 aav 입자를 포함하는 약제학적 조성물 |
| CN109415730A (zh) | 2016-06-13 | 2019-03-01 | 北卡罗来纳大学教堂山分校 | 优化的cln1基因和表达盒以及它们的应用 |
| JP7048585B2 (ja) * | 2016-09-22 | 2022-04-05 | ソルボンヌ・ユニヴェルシテ | 網膜変性疾患の処置に使用するための光遺伝学的に形質転換した光受容体前駆細胞 |
| AU2018350990A1 (en) * | 2017-10-18 | 2020-05-21 | Regenxbio Inc. | Treatment of ocular diseases and metastatic colon cancer with human post-translationally modified VEGF-Trap |
-
2020
- 2020-04-15 US US17/611,972 patent/US20220233655A1/en not_active Abandoned
- 2020-04-15 AR ARP200101063A patent/AR118696A1/es unknown
- 2020-04-15 CN CN202080051735.0A patent/CN114126667A/zh active Pending
- 2020-04-15 WO PCT/US2020/028207 patent/WO2020236351A1/en not_active Ceased
- 2020-04-15 CA CA3141017A patent/CA3141017A1/en active Pending
- 2020-04-15 EP EP20727414.3A patent/EP3969060A1/en active Pending
- 2020-04-15 JP JP2021568543A patent/JP2022533645A/ja active Pending
- 2020-04-15 CA CA3141020A patent/CA3141020A1/en active Pending
- 2020-04-15 TW TW109112715A patent/TW202110486A/zh unknown
- 2020-04-15 EP EP20723738.9A patent/EP3969059A1/en active Pending
- 2020-04-15 WO PCT/US2020/028352 patent/WO2020236352A1/en not_active Ceased
- 2020-04-15 JP JP2021568813A patent/JP7707081B2/ja active Active
- 2020-04-15 AU AU2020278960A patent/AU2020278960A1/en active Pending
- 2020-04-15 KR KR1020217040926A patent/KR20220009427A/ko not_active Withdrawn
- 2020-04-15 US US17/611,982 patent/US20220226507A1/en not_active Abandoned
- 2020-04-15 AU AU2020278499A patent/AU2020278499A1/en active Pending
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