JP2022530037A5 - - Google Patents

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Publication number
JP2022530037A5
JP2022530037A5 JP2021562962A JP2021562962A JP2022530037A5 JP 2022530037 A5 JP2022530037 A5 JP 2022530037A5 JP 2021562962 A JP2021562962 A JP 2021562962A JP 2021562962 A JP2021562962 A JP 2021562962A JP 2022530037 A5 JP2022530037 A5 JP 2022530037A5
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JP
Japan
Prior art keywords
item
tcr
nucleic acid
acid molecule
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021562962A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022530037A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/029344 external-priority patent/WO2020219563A1/en
Publication of JP2022530037A publication Critical patent/JP2022530037A/ja
Publication of JP2022530037A5 publication Critical patent/JP2022530037A5/ja
Pending legal-status Critical Current

Links

JP2021562962A 2019-04-22 2020-04-22 融合タンパク質を使用するtcr再プログラミングのための組成物及び方法 Pending JP2022530037A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962836977P 2019-04-22 2019-04-22
US62/836,977 2019-04-22
US201962943679P 2019-12-04 2019-12-04
US62/943,679 2019-12-04
PCT/US2020/029344 WO2020219563A1 (en) 2019-04-22 2020-04-22 Compositions and methods for tcr reprogramming using fusion proteins

Publications (2)

Publication Number Publication Date
JP2022530037A JP2022530037A (ja) 2022-06-27
JP2022530037A5 true JP2022530037A5 (https=) 2023-04-28

Family

ID=72941760

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021562962A Pending JP2022530037A (ja) 2019-04-22 2020-04-22 融合タンパク質を使用するtcr再プログラミングのための組成物及び方法

Country Status (7)

Country Link
US (1) US20220362295A1 (https=)
EP (1) EP3959322A4 (https=)
JP (1) JP2022530037A (https=)
CN (1) CN114258430A (https=)
AU (1) AU2020262111A1 (https=)
CA (1) CA3137519A1 (https=)
WO (1) WO2020219563A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3298033T5 (pl) 2015-05-18 2023-10-30 TCR2 Therapeutics Inc. Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych
WO2017222911A1 (en) 2016-06-20 2017-12-28 The Board Of Trustees Of The Leland Stanford Junior University Circular rnas and their use in immunomodulation
US20220288176A1 (en) * 2019-08-28 2022-09-15 The Board Of Trustees Of The Leland Stanford Junior University Circular rna modification and methods of use
KR20230028375A (ko) 2020-06-25 2023-02-28 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 원형 rna 번역을 구동하는 유전 요소와 이를 사용하는 방법
GB202011993D0 (en) 2020-07-31 2020-09-16 Adc Therapeutics Sa ANTI-IL 13Ra2 antibodies
EP3964585A1 (en) * 2020-09-03 2022-03-09 Miltenyi Biotec B.V. & Co. KG Cd62l specific lentiviral vector particle for targeted transduction of t cell subsets
CA3197316A1 (en) * 2020-09-29 2022-04-07 NeuExcell Therapeutics Inc. Neurod1 and dlx2 vector
CN114516913B (zh) * 2020-11-19 2023-04-28 东莞市朋志生物科技有限公司 抗n末端脑钠肽前体的抗体和检测试剂盒
WO2022116528A1 (zh) * 2020-12-04 2022-06-09 苏州科锐迈德生物医药科技有限公司 环状rna、包含环状rna的疫苗及用于检测新型冠状病毒中和抗体的试剂盒
CN112481289B (zh) 2020-12-04 2023-06-27 苏州科锐迈德生物医药科技有限公司 一种转录环状rna的重组核酸分子及其在蛋白表达中的应用
JPWO2023027082A1 (https=) * 2021-08-23 2023-03-02
WO2023070043A1 (en) * 2021-10-20 2023-04-27 Yale University Compositions and methods for targeted editing and evolution of repetitive genetic elements
JP2025504398A (ja) * 2022-01-10 2025-02-12 リジェネロン・ファーマシューティカルズ・インコーポレイテッド Muc16キメラ抗原受容体
CN114606263B (zh) * 2022-05-11 2022-09-06 上海优替济生生物医药有限公司 分离的核酸分子及其用途
JP2025530303A (ja) * 2022-09-10 2025-09-11 エクスクルサーク・(スージョウ)・バイオメディカル・カンパニー・リミテッド 環状rna及びその調製方法
CN116411023B (zh) * 2023-02-24 2025-08-12 北京大学人民医院 一种新型环状rna成环序列构建car-t细胞及在治疗小细胞肺癌中的应用
WO2024215872A1 (en) * 2023-04-11 2024-10-17 The Regents Of The University Of California Human t cell receptors targeting tumor-enhanced splicing epitopes on hla-a*02:01 for small cell carcinoma
WO2024236366A2 (en) * 2023-05-12 2024-11-21 Sekkei Bio Private Limited Design and method of generating scarless circular rna

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015034925A1 (en) * 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Circular polynucleotides
PL3298033T5 (pl) * 2015-05-18 2023-10-30 TCR2 Therapeutics Inc. Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych
ES2891578T3 (es) * 2016-04-01 2022-01-28 Kite Pharma Inc Antígeno quimérico y receptores de células T y métodos de uso
WO2018067993A1 (en) * 2016-10-07 2018-04-12 TCR2 Therapeutics Inc. Compositions and methods for t-cell receptors reprogramming using fusion proteins
WO2018232020A1 (en) * 2017-06-13 2018-12-20 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
WO2019222275A2 (en) * 2018-05-14 2019-11-21 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using inducible fusion proteins

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