JP2021515598A5 - - Google Patents
Info
- Publication number
- JP2021515598A5 JP2021515598A5 JP2020571330A JP2020571330A JP2021515598A5 JP 2021515598 A5 JP2021515598 A5 JP 2021515598A5 JP 2020571330 A JP2020571330 A JP 2020571330A JP 2020571330 A JP2020571330 A JP 2020571330A JP 2021515598 A5 JP2021515598 A5 JP 2021515598A5
- Authority
- JP
- Japan
- Prior art keywords
- tcr
- domain
- nucleic acid
- endogenous
- recombinant nucleic
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862641159P | 2018-03-09 | 2018-03-09 | |
| US62/641,159 | 2018-03-09 | ||
| PCT/US2019/021315 WO2019173693A1 (en) | 2018-03-09 | 2019-03-08 | Compositions and methods for tcr reprogramming using fusion proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021515598A JP2021515598A (ja) | 2021-06-24 |
| JP2021515598A5 true JP2021515598A5 (https=) | 2022-03-16 |
| JPWO2019173693A5 JPWO2019173693A5 (https=) | 2022-03-16 |
Family
ID=67846339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020571330A Withdrawn JP2021515598A (ja) | 2018-03-09 | 2019-03-08 | 融合タンパク質を用いたｔｃｒリプログラミングのための組成物及び方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210361704A1 (https=) |
| EP (1) | EP3765039A4 (https=) |
| JP (1) | JP2021515598A (https=) |
| KR (1) | KR20200130383A (https=) |
| CN (1) | CN111954714A (https=) |
| AU (1) | AU2019231792A1 (https=) |
| BR (1) | BR112020018173A2 (https=) |
| CA (1) | CA3093449A1 (https=) |
| EA (1) | EA202092093A1 (https=) |
| MX (1) | MX2020009371A (https=) |
| SG (1) | SG11202008721SA (https=) |
| WO (1) | WO2019173693A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107995913B (zh) | 2015-05-18 | 2022-02-11 | T细胞受体治疗公司 | 使用融合蛋白对tcr重编程的组合物和方法 |
| EP3494138A1 (en) | 2016-08-02 | 2019-06-12 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| CA3036745A1 (en) | 2016-10-07 | 2018-04-12 | TCR2 Therapeutics Inc. | Compositions and methods for t-cell receptors reprogramming using fusion proteins |
| US11851491B2 (en) | 2016-11-22 | 2023-12-26 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
| AU2020271523A1 (en) * | 2019-04-11 | 2021-10-14 | Fate Therapeutics, Inc. | CD3 reconstitution in engineered iPSC and immune effector cells |
| WO2021035170A1 (en) * | 2019-08-21 | 2021-02-25 | Precision Biosciences, Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| CA3154287A1 (en) * | 2019-09-12 | 2021-03-18 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| KR20220095228A (ko) * | 2019-11-06 | 2022-07-06 | 베이롤 칼리지 오브 메드신 | 암의 t 세포 치료를 위한 세포독성 효과기 기억 t 세포를 생산하는 방법 |
| US20230069322A1 (en) * | 2019-12-24 | 2023-03-02 | TCR2 Therapeutics Inc. | Compositions and methods for gamma delta tcr reprogramming using fusion proteins |
| WO2022034375A1 (en) * | 2020-08-12 | 2022-02-17 | Migal Galilee Research Institute Ltd. | Alloreactive immune cell-distancing device and uses thereof for protecting donor-derived cells from allorejection |
| CA3203180A1 (en) * | 2020-12-23 | 2022-06-30 | Robert Tighe | Compositions and methods for tcr reprogramming using fusion proteins |
| CN117480247A (zh) * | 2021-04-15 | 2024-01-30 | 恺兴生命科技(上海)有限公司 | 嵌合t细胞受体及其应用 |
| WO2023179795A1 (zh) * | 2022-03-25 | 2023-09-28 | 立凌生物制药(苏州)有限公司 | 一种快速且简便地获得正确配对tcr的方法以及获得的tcr |
| WO2023246911A1 (zh) * | 2022-06-24 | 2023-12-28 | 北京可瑞生物科技有限公司 | 基于t细胞受体的双特异性多肽分子及其用途 |
| CN120957739A (zh) * | 2022-12-23 | 2025-11-14 | 天科雅生物科技有限公司 | 工程化t细胞受体和表达所述工程化t细胞受体的工程化免疫细胞 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003068822A2 (en) * | 2002-02-13 | 2003-08-21 | Micromet Ag | De-immunized (poly)peptide constructs |
| WO2011059836A2 (en) * | 2009-10-29 | 2011-05-19 | Trustees Of Dartmouth College | T cell receptor-deficient t cell compositions |
| KR102437522B1 (ko) * | 2012-05-25 | 2022-08-26 | 셀렉티스 | 면역요법을 위한 동종이형 및 면역억제제 저항성인 ｔ 세포의 조작 방법 |
| CN107995913B (zh) * | 2015-05-18 | 2022-02-11 | T细胞受体治疗公司 | 使用融合蛋白对tcr重编程的组合物和方法 |
| EP3468997B1 (en) * | 2016-06-08 | 2023-09-13 | Xencor, Inc. | Treatment of igg4-related diseases with anti-cd19 antibodies crossbinding to cd32b |
| US11851491B2 (en) * | 2016-11-22 | 2023-12-26 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
| JP2020513754A (ja) * | 2016-12-21 | 2020-05-21 | ティーシーアール２ セラピューティクス インク． | がん治療用に操作されたｔ細胞 |
-
2019
- 2019-03-08 CA CA3093449A patent/CA3093449A1/en active Pending
- 2019-03-08 CN CN201980023038.1A patent/CN111954714A/zh active Pending
- 2019-03-08 EP EP19763494.2A patent/EP3765039A4/en not_active Withdrawn
- 2019-03-08 WO PCT/US2019/021315 patent/WO2019173693A1/en not_active Ceased
- 2019-03-08 BR BR112020018173-0A patent/BR112020018173A2/pt not_active IP Right Cessation
- 2019-03-08 JP JP2020571330A patent/JP2021515598A/ja not_active Withdrawn
- 2019-03-08 KR KR1020207028766A patent/KR20200130383A/ko not_active Abandoned
- 2019-03-08 EA EA202092093A patent/EA202092093A1/ru unknown
- 2019-03-08 US US16/979,380 patent/US20210361704A1/en not_active Abandoned
- 2019-03-08 MX MX2020009371A patent/MX2020009371A/es unknown
- 2019-03-08 AU AU2019231792A patent/AU2019231792A1/en not_active Abandoned
- 2019-03-08 SG SG11202008721SA patent/SG11202008721SA/en unknown
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