JP2022529784A5 - - Google Patents
Info
- Publication number
- JP2022529784A5 JP2022529784A5 JP2021562003A JP2021562003A JP2022529784A5 JP 2022529784 A5 JP2022529784 A5 JP 2022529784A5 JP 2021562003 A JP2021562003 A JP 2021562003A JP 2021562003 A JP2021562003 A JP 2021562003A JP 2022529784 A5 JP2022529784 A5 JP 2022529784A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- cell
- composition according
- permeable
- cargo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1904115 | 2019-04-17 | ||
| FR1904115 | 2019-04-17 | ||
| PCT/US2020/028572 WO2020214846A1 (en) | 2019-04-17 | 2020-04-16 | Peptides and nanoparticles for intracellular delivery of molecules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022529784A JP2022529784A (ja) | 2022-06-24 |
| JP2022529784A5 true JP2022529784A5 (enExample) | 2023-04-24 |
| JP7715638B2 JP7715638B2 (ja) | 2025-07-30 |
Family
ID=72837882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021562003A Active JP7715638B2 (ja) | 2019-04-17 | 2020-04-16 | 分子を細胞内送達するためのペプチドおよびナノ粒子 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US12357695B2 (enExample) |
| EP (1) | EP3955967A4 (enExample) |
| JP (1) | JP7715638B2 (enExample) |
| CN (1) | CN114007654A (enExample) |
| AU (1) | AU2020259449A1 (enExample) |
| CA (1) | CA3137137A1 (enExample) |
| IL (1) | IL287321A (enExample) |
| MX (2) | MX2021012740A (enExample) |
| WO (1) | WO2020214846A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3955967A4 (en) | 2019-04-17 | 2023-06-07 | Aadigen, LLC | PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF MOLECULES |
| WO2023081893A1 (en) * | 2021-11-08 | 2023-05-11 | Entrada Therapeutics, Inc. | Intracellular targeting of oligonucleotides |
| WO2023111213A1 (en) | 2021-12-16 | 2023-06-22 | Rdp Pharma Ag | Cell penetrating polypeptides (cpps) and their use in human therapy |
| WO2023248846A1 (ja) * | 2022-06-22 | 2023-12-28 | 東亞合成株式会社 | キャリアペプチドフラグメント及びその利用 |
| NL2033185B1 (en) * | 2022-09-29 | 2024-04-08 | Stichting Vu | Compounds for rna stabilisation and delivery |
| WO2024187174A2 (en) * | 2023-03-09 | 2024-09-12 | Aadigen, Llc | Compositions for treating cancer with kras mutations and uses thereof |
| EP4480497A1 (en) | 2023-06-21 | 2024-12-25 | RDP Pharma AG | Bio-conjugates for oncology |
| WO2025193628A2 (en) * | 2024-03-09 | 2025-09-18 | Aadigen, Llc | Compositions for treating cancer with kras mutations and uses thereof |
| FR3163973A1 (fr) | 2024-06-27 | 2026-01-02 | Safran Aircraft Engines | Compresseur axial a traitement de carter pour une turbomachine d’aeronef |
| CN119954937B (zh) * | 2024-12-26 | 2025-09-12 | 东北农业大学 | 一种源自节肢蛋白的抗菌肽及其制备方法和应用 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003295600A1 (en) | 2002-11-14 | 2004-06-15 | Dharmacon, Inc. | Functional and hyperfunctional sirna |
| US7514530B2 (en) | 2004-04-26 | 2009-04-07 | Centre National De La Recherche Scientifique | Peptide carrier for delivering siRNA into mammalian cells |
| US7579318B2 (en) | 2005-12-06 | 2009-08-25 | Centre De La Recherche De La Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| EP2331566B1 (en) | 2008-08-26 | 2015-10-07 | City of Hope | Method and compositions for enhanced anti-tumor effector functioning of t cells |
| US8889394B2 (en) | 2009-09-07 | 2014-11-18 | Empire Technology Development Llc | Multiple domain proteins |
| DK2631291T3 (da) | 2010-10-22 | 2019-06-11 | Olix Pharmaceuticals Inc | Nukleinsyremolekyler, der inducerer rna-interferens, og anvendelser deraf |
| WO2012129352A1 (en) | 2011-03-21 | 2012-09-27 | Yale University | The kras variant and tumor biology |
| WO2012137036A1 (en) | 2011-04-04 | 2012-10-11 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| EP3375457B1 (en) | 2011-11-24 | 2020-06-24 | Positec Power Tools (Suzhou) Co., Ltd | Peptide sequence design and use thereof for peptide-mediated sirna delivery |
| JP2013212052A (ja) | 2012-03-30 | 2013-10-17 | Yale Univ | Ｋｒａｓバリアントおよび腫瘍生物学 |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| WO2013151665A2 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| WO2013150338A1 (en) | 2012-04-04 | 2013-10-10 | Centre National De La Recherche Scientifique | Stapled cell penetrating peptides for intracellular delivery of molecules |
| RU2766608C2 (ru) | 2012-04-11 | 2022-03-15 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| CA2878314A1 (en) | 2012-07-16 | 2014-01-23 | Kyowa Hakko Kirin Co., Ltd. | Rnai pharmaceutical composition for suppressing expression of kras gene |
| WO2014053880A1 (en) * | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053879A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053882A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| WO2014053881A1 (en) | 2012-10-04 | 2014-04-10 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| US20150329640A1 (en) | 2012-12-20 | 2015-11-19 | Bluebird Bio, Inc. | Chimeric antigen receptors and immune cells targeting b cell malignancies |
| ITRM20130054A1 (it) | 2013-01-30 | 2014-07-31 | Paolo Gresele | Piastrine trasfettate con materiale genetico esogeno e microparticelle derivate da dette piastrine trasfettate, metodo per la loro preparazione e loro usi. |
| DK2956175T3 (da) | 2013-02-15 | 2017-11-27 | Univ California | Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf |
| MX387665B (es) | 2014-12-24 | 2025-03-18 | Aadigen Llc | Péptidos, complejos, moléculas de carga y nanopartículas que contienen los mismos. |
| WO2017179660A1 (ja) | 2016-04-14 | 2017-10-19 | 国立大学法人岐阜大学 | マイクロｒｎａ－１４３誘導体 |
| CA3025523A1 (en) | 2016-05-27 | 2017-11-30 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of genome-editing molecules |
| US20190211317A1 (en) | 2016-05-27 | 2019-07-11 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of genome-editing molecules |
| AU2018313940A1 (en) | 2017-08-10 | 2020-03-05 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of virus |
| AU2018352221B2 (en) | 2017-10-16 | 2024-04-18 | Aadigen, Llc | Peptides and nanoparticles for intracellular delivery of mRNA |
| EP3955967A4 (en) | 2019-04-17 | 2023-06-07 | Aadigen, LLC | PEPTIDES AND NANOPARTICLES FOR INTRACELLULAR DELIVERY OF MOLECULES |
| US20230167437A1 (en) | 2020-04-24 | 2023-06-01 | Aadigen, Llc | Compositions for treating cancer with kras mutations and uses thereof |
| WO2022020782A1 (en) | 2020-07-24 | 2022-01-27 | Aadigen, Llc | Compositions and methods for treating viral infections |
-
2020
- 2020-04-16 EP EP20792117.2A patent/EP3955967A4/en active Pending
- 2020-04-16 AU AU2020259449A patent/AU2020259449A1/en active Pending
- 2020-04-16 JP JP2021562003A patent/JP7715638B2/ja active Active
- 2020-04-16 CA CA3137137A patent/CA3137137A1/en active Pending
- 2020-04-16 MX MX2021012740A patent/MX2021012740A/es unknown
- 2020-04-16 US US17/594,454 patent/US12357695B2/en active Active
- 2020-04-16 CN CN202080044200.0A patent/CN114007654A/zh active Pending
- 2020-04-16 WO PCT/US2020/028572 patent/WO2020214846A1/en not_active Ceased
-
2021
- 2021-10-17 IL IL287321A patent/IL287321A/en unknown
- 2021-10-18 MX MX2026002684A patent/MX2026002684A/es unknown
-
2025
- 2025-06-11 US US19/235,292 patent/US20250302963A1/en active Pending
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