JP2022529311A5 - - Google Patents
Info
- Publication number
- JP2022529311A5 JP2022529311A5 JP2021556882A JP2021556882A JP2022529311A5 JP 2022529311 A5 JP2022529311 A5 JP 2022529311A5 JP 2021556882 A JP2021556882 A JP 2021556882A JP 2021556882 A JP2021556882 A JP 2021556882A JP 2022529311 A5 JP2022529311 A5 JP 2022529311A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- deuterium
- pharmaceutically acceptable
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962824144P | 2019-03-26 | 2019-03-26 | |
| US62/824,144 | 2019-03-26 | ||
| PCT/US2020/024746 WO2020198379A1 (en) | 2019-03-26 | 2020-03-25 | Tyk2 pseudokinase ligands |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022529311A JP2022529311A (ja) | 2022-06-21 |
| JP2022529311A5 true JP2022529311A5 (enExample) | 2023-03-31 |
| JP7595582B2 JP7595582B2 (ja) | 2024-12-06 |
Family
ID=72612101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021556882A Active JP7595582B2 (ja) | 2019-03-26 | 2020-03-25 | Ｔｙｋ２偽キナーゼリガンド |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11780842B2 (enExample) |
| EP (1) | EP3946350A4 (enExample) |
| JP (1) | JP7595582B2 (enExample) |
| KR (1) | KR20220004641A (enExample) |
| CN (1) | CN113874021B (enExample) |
| AU (1) | AU2020247990A1 (enExample) |
| BR (1) | BR112021019070A2 (enExample) |
| CA (1) | CA3134814A1 (enExample) |
| EA (1) | EA202192625A1 (enExample) |
| IL (1) | IL286635A (enExample) |
| MX (1) | MX2021011723A (enExample) |
| SG (1) | SG11202110523XA (enExample) |
| WO (1) | WO2020198379A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS66346B1 (sr) | 2018-10-22 | 2025-01-31 | Alumis Inc | Inhibitori tyk2 i njihova upotreba |
| US20220177486A1 (en) * | 2019-03-11 | 2022-06-09 | Esker Therapeutics, Inc. | Tyk2 inhibitors and uses thereof |
| SG11202110523XA (en) | 2019-03-26 | 2021-10-28 | Ventyx Biosciences Inc | Tyk2 pseudokinase ligands |
| CN114929226B (zh) * | 2019-11-08 | 2024-09-27 | 温缇克斯生物科学公司 | Tyk2假激酶配体 |
| IL301385A (en) * | 2020-09-16 | 2023-05-01 | Alumis Inc | TYK2 inhibitors and their use |
| WO2022117090A1 (zh) * | 2020-12-03 | 2022-06-09 | 成都科岭源医药技术有限公司 | 一种多环化合物及其制备方法和用途 |
| KR20240111312A (ko) | 2021-10-25 | 2024-07-16 | 카이메라 쎄라퓨틱스 인코포레이티드 | Tyk2 분해제 및 이의 용도 |
| WO2023208244A1 (zh) * | 2022-04-29 | 2023-11-02 | 南京明德新药研发有限公司 | 大环类化合物及其应用 |
| CN118084923A (zh) * | 2022-11-17 | 2024-05-28 | 中国科学院上海有机化学研究所 | 作为lrrk2激酶抑制剂的环状化合物及其制备方法 |
| EP4692096A4 (en) * | 2023-03-31 | 2026-07-22 | Prime Gene Therapeutics Co Ltd | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION AND ITS USE |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7196078B2 (en) | 2002-09-04 | 2007-03-27 | Schering Corpoartion | Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| US8580782B2 (en) | 2002-09-04 | 2013-11-12 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
| US7161003B1 (en) | 2002-09-04 | 2007-01-09 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| US7119200B2 (en) | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| JP4564485B2 (ja) | 2003-02-28 | 2010-10-20 | 帝人ファーマ株式会社 | ピラゾロ［１，５−ａ］ピリミジン誘導体 |
| US20070082900A1 (en) | 2005-10-06 | 2007-04-12 | Schering Corporation | Methods for inhibiting protein kinases |
| US7517882B2 (en) | 2006-09-18 | 2009-04-14 | Polaris Group | Protein kinase inhibitors |
| WO2010118207A1 (en) | 2009-04-09 | 2010-10-14 | Schering Corporation | Pyrazolo [1, 5-a] pyrimidine derivatives as mtor inhibitors |
| BR122019024201B1 (pt) | 2010-05-20 | 2021-08-03 | Array Biopharma Inc | Composto macrocíclico como inibidores de trk quinase, seu uso, e composição farmacêutica |
| WO2015112806A2 (en) | 2014-01-24 | 2015-07-30 | Tp Therapeutics, Inc. | Diaryl macrocycles as modulators of protein kinases |
| RU2732405C2 (ru) | 2015-07-02 | 2020-09-16 | Тёрнинг Поинт Терапьютикс, Инк. | Хиральные диарильные макроциклы в качестве модуляторов протеинкиназ |
| RS63359B1 (sr) | 2015-11-06 | 2022-07-29 | Incyte Corp | Heterociklična jedinjenja kao inhibitori pi3k-gama |
| AU2017302019A1 (en) | 2016-07-28 | 2019-02-07 | Turning Point Therapeutics, Inc. | Macrocycle kinase inhibitors |
| KR102477063B1 (ko) * | 2016-10-28 | 2022-12-12 | 브리스톨-마이어스 스큅 컴퍼니 | Il-12, il-23 및/또는 ifn 알파 반응의 조정제로서 유용한 헤테로비시클릭 화합물 |
| AU2018230737B2 (en) | 2017-03-08 | 2022-09-22 | Takeda Pharmaceutical Company Limited | Tyk2 inhibitors, uses, and methods for production thereof |
| JOP20190213A1 (ar) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | مركبات حلقية ضخمة كمثبطات لكيناز ros1 |
| WO2018213365A1 (en) | 2017-05-15 | 2018-11-22 | Dana-Farber Cancer Institute, Inc. | Compounds for treating dengue virus infection and other viral infections |
| IL317854A (en) * | 2017-07-28 | 2025-02-01 | Takeda Pharmaceuticals Co | TYK2 inhibitors and their uses |
| EP3849981B1 (en) | 2018-09-10 | 2023-02-01 | Eli Lilly and Company | Pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives useful in the treatment of psoriasis and systemic lupus erythematosus |
| JP7619951B2 (ja) | 2018-10-15 | 2025-01-22 | 武田薬品工業株式会社 | Ｔｙｋ２阻害剤およびその使用 |
| TWI800696B (zh) | 2018-12-10 | 2023-05-01 | 美商美國禮來大藥廠 | 7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物 |
| SG11202108619SA (en) | 2019-02-07 | 2021-09-29 | Ventyx Biosciences Inc | Tyk2 pseudokinase ligands |
| US20220177486A1 (en) | 2019-03-11 | 2022-06-09 | Esker Therapeutics, Inc. | Tyk2 inhibitors and uses thereof |
| SG11202110523XA (en) | 2019-03-26 | 2021-10-28 | Ventyx Biosciences Inc | Tyk2 pseudokinase ligands |
| CN114929226B (zh) | 2019-11-08 | 2024-09-27 | 温缇克斯生物科学公司 | Tyk2假激酶配体 |
-
2020
- 2020-03-25 SG SG11202110523XA patent/SG11202110523XA/en unknown
- 2020-03-25 EA EA202192625A patent/EA202192625A1/ru unknown
- 2020-03-25 CA CA3134814A patent/CA3134814A1/en active Pending
- 2020-03-25 JP JP2021556882A patent/JP7595582B2/ja active Active
- 2020-03-25 AU AU2020247990A patent/AU2020247990A1/en not_active Abandoned
- 2020-03-25 MX MX2021011723A patent/MX2021011723A/es unknown
- 2020-03-25 EP EP20777561.0A patent/EP3946350A4/en active Pending
- 2020-03-25 CN CN202080038590.0A patent/CN113874021B/zh active Active
- 2020-03-25 KR KR1020217034394A patent/KR20220004641A/ko not_active Ceased
- 2020-03-25 BR BR112021019070A patent/BR112021019070A2/pt not_active Application Discontinuation
- 2020-03-25 WO PCT/US2020/024746 patent/WO2020198379A1/en not_active Ceased
- 2020-03-25 US US17/441,788 patent/US11780842B2/en active Active
-
2021
- 2021-09-23 IL IL286635A patent/IL286635A/en unknown
-
2023
- 2023-08-28 US US18/457,070 patent/US20230406858A1/en not_active Abandoned
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