JP2022526420A5 - - Google Patents

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Publication number
JP2022526420A5
JP2022526420A5 JP2021559535A JP2021559535A JP2022526420A5 JP 2022526420 A5 JP2022526420 A5 JP 2022526420A5 JP 2021559535 A JP2021559535 A JP 2021559535A JP 2021559535 A JP2021559535 A JP 2021559535A JP 2022526420 A5 JP2022526420 A5 JP 2022526420A5
Authority
JP
Japan
Prior art keywords
seq
chain variable
variable region
polypeptide sequence
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021559535A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022526420A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/025643 external-priority patent/WO2020210067A1/en
Publication of JP2022526420A publication Critical patent/JP2022526420A/ja
Publication of JP2022526420A5 publication Critical patent/JP2022526420A5/ja
Pending legal-status Critical Current

Links

JP2021559535A 2019-04-08 2020-03-30 ヒト化抗dll3キメラ抗原受容体及びその使用 Pending JP2022526420A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962830598P 2019-04-08 2019-04-08
US62/830,598 2019-04-08
US201962861377P 2019-06-14 2019-06-14
US62/861,377 2019-06-14
US201962896790P 2019-09-06 2019-09-06
US62/896,790 2019-09-06
US201962928615P 2019-10-31 2019-10-31
US62/928,615 2019-10-31
PCT/US2020/025643 WO2020210067A1 (en) 2019-04-08 2020-03-30 Humanized anti-dll3 chimeric antigen receptors and uses thereof

Publications (2)

Publication Number Publication Date
JP2022526420A JP2022526420A (ja) 2022-05-24
JP2022526420A5 true JP2022526420A5 (enExample) 2022-06-15

Family

ID=72750831

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021559535A Pending JP2022526420A (ja) 2019-04-08 2020-03-30 ヒト化抗dll3キメラ抗原受容体及びその使用

Country Status (12)

Country Link
US (1) US20220184127A1 (enExample)
EP (1) EP3952888A1 (enExample)
JP (1) JP2022526420A (enExample)
KR (1) KR20210150432A (enExample)
CN (1) CN113795262A (enExample)
AU (1) AU2020271012A1 (enExample)
BR (1) BR112021016272A2 (enExample)
CA (1) CA3132202A1 (enExample)
IL (1) IL286984A (enExample)
MX (1) MX2021012336A (enExample)
SG (1) SG11202108759SA (enExample)
WO (1) WO2020210067A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
JP7181438B2 (ja) * 2019-08-06 2022-11-30 アプリノイア セラピューティクス リミテッド 病理学的タウ種に結合する抗体及びその使用
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
MX2023012614A (es) * 2021-05-08 2023-11-03 Shanghai Qilu Pharmaceutical Res And Development Centre Ltd Molecula de union contra dll3 y uso de la misma.
AU2022339815A1 (en) * 2021-09-02 2024-03-14 Memorial Hospital For Cancer And Allied Diseases Antigen recognizing receptors targeting dll3 and uses thereof
CN114790240B (zh) * 2022-06-10 2023-06-06 郑州大学 SARS-CoV-2中和性单克隆抗体及应用
WO2024044779A2 (en) * 2022-08-26 2024-02-29 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for delta-like ligand 3 (dll3)
CN116813784B (zh) * 2023-05-17 2024-03-01 星奕昂(上海)生物科技有限公司 靶向dll3的抗体及其应用
CN120731224A (zh) * 2024-01-30 2025-09-30 石药集团巨石生物制药有限公司 抗dll3抗体及应用
WO2025212519A1 (en) * 2024-04-01 2025-10-09 Moonlight Bio, Inc. Dll3 binding proteins and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY149079A (en) * 2006-10-02 2013-07-15 Regeneron Pharma High affinity human antibodies to human il-4 receptor
AU2010303443A1 (en) * 2009-10-09 2012-04-19 Merck Sharp & Dohme Corp. Generation, characterization and uses thereof of anti-Her 3 antibodies
DK2530091T3 (en) * 2010-01-29 2018-05-28 Chugai Pharmaceutical Co Ltd ANTI-DLL3 ANTIBODY
CA2799746C (en) * 2010-05-17 2020-11-24 Sai Reddy Rapid isolation of monoclonal antibodies from animals
WO2012019061A2 (en) * 2010-08-05 2012-02-09 Stem Centrx, Inc. Novel effectors and methods of use
JP2014529581A (ja) * 2011-08-05 2014-11-13 イフォム・フォンダツィオーネ・インスティトゥオ・フィルチ・ディ・オンコロジア・モレコラーレ 構成的に活性なuPARバリアントならびに阻害抗体の生成および単離へのそれの使用
BR112014020826A8 (pt) * 2012-02-24 2017-09-19 Stem Centrx Inc Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco – anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado
CN103173413A (zh) * 2012-12-07 2013-06-26 天津三箭生物技术有限公司 小鼠抗人β-Catenin单克隆抗体及分泌该单克隆抗体的杂交瘤细胞株
GB201302447D0 (en) * 2013-02-12 2013-03-27 Oxford Biotherapeutics Ltd Therapeutic and diagnostic target
US9879087B2 (en) * 2014-11-12 2018-01-30 Siamab Therapeutics, Inc. Glycan-interacting compounds and methods of use
MA41613A (fr) * 2015-02-23 2018-01-02 Abbvie Stemcentrx Llc Récepteurs antigéniques chimériques anti-dll3 et procédés d'utilisation desdits récepteurs
TWI793062B (zh) * 2015-07-31 2023-02-21 德商安美基研究(慕尼黑)公司 Dll3及cd3抗體構築體
WO2019067805A1 (en) * 2017-09-27 2019-04-04 University Of Southern California NEW PLATFORMS FOR CO-STIMULATION, NEW CAR DESIGNS AND OTHER IMPROVEMENTS FOR ADOPTIVE CELL THERAPY
CA3097193A1 (en) * 2018-05-08 2019-11-14 Phanes Therapeutics, Inc. Anti-dll3 antibodies and uses thereof

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