JP2022524759A5 - - Google Patents
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- Publication number
- JP2022524759A5 JP2022524759A5 JP2021553031A JP2021553031A JP2022524759A5 JP 2022524759 A5 JP2022524759 A5 JP 2022524759A5 JP 2021553031 A JP2021553031 A JP 2021553031A JP 2021553031 A JP2021553031 A JP 2021553031A JP 2022524759 A5 JP2022524759 A5 JP 2022524759A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19161323 | 2019-03-07 | ||
| EP19161323.1 | 2019-03-07 | ||
| US201962879597P | 2019-07-29 | 2019-07-29 | |
| US62/879,597 | 2019-07-29 | ||
| PCT/US2020/021726 WO2020181283A1 (en) | 2019-03-07 | 2020-03-09 | Carboxamide-pyrimidine derivatives as shp2 antagonists |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022524759A JP2022524759A (ja) | 2022-05-10 |
| JPWO2020181283A5 JPWO2020181283A5 (https=) | 2023-03-15 |
| JP2022524759A5 true JP2022524759A5 (https=) | 2023-03-15 |
| JP7734586B2 JP7734586B2 (ja) | 2025-09-05 |
Family
ID=70057354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021553031A Active JP7734586B2 (ja) | 2019-03-07 | 2020-03-09 | Ｓｈｐ２アンタゴニストとしてのカルボキサミド－ピリミジン誘導体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11033547B2 (https=) |
| EP (1) | EP3935049A1 (https=) |
| JP (1) | JP7734586B2 (https=) |
| CN (1) | CN113795483B (https=) |
| AU (1) | AU2020232026B2 (https=) |
| CA (1) | CA3127361A1 (https=) |
| IL (1) | IL286077A (https=) |
| WO (1) | WO2020181283A1 (https=) |
Families Citing this family (37)
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| MX2023002248A (es) | 2020-09-03 | 2023-05-16 | Revolution Medicines Inc | Uso de inhibidores de sos1 para tratar neoplasias malignas con mutaciones de shp2. |
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| CA3217393A1 (en) | 2021-05-05 | 2022-11-10 | Elena S. Koltun | Ras inhibitors |
| AU2022268962A1 (en) | 2021-05-05 | 2023-12-14 | Revolution Medicines, Inc. | Ras inhibitors for the treatment of cancer |
| MX2023012929A (es) * | 2021-05-05 | 2023-11-13 | Huyabio Int Llc | Terapias de combinacion que comprenden inhibidores de shp2 e inhibidores de tirosina cinasa egfr. |
| WO2022235866A1 (en) | 2021-05-05 | 2022-11-10 | Revolution Medicines, Inc. | Covalent ras inhibitors and uses thereof |
| WO2022259157A1 (en) | 2021-06-09 | 2022-12-15 | Novartis Ag | A triple pharmaceutical combination comprising dabrafenib, trametinib and a shp2 inhibitor |
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| AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
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| KR20250172857A (ko) | 2023-04-14 | 2025-12-09 | 레볼루션 메디슨즈, 인크. | Ras 억제제의 결정형 |
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| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
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| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| CN120842203B (zh) * | 2025-09-24 | 2025-12-05 | 山东大学 | 特异性检测shp2的近红外荧光探针的制备方法和应用 |
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| CN115916765B (zh) * | 2020-07-10 | 2025-04-18 | 浙江海正药业股份有限公司 | 吡啶或嘧啶类衍生物及其制备方法和用途 |
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2020
- 2020-03-09 CA CA3127361A patent/CA3127361A1/en active Pending
- 2020-03-09 CN CN202080033849.2A patent/CN113795483B/zh active Active
- 2020-03-09 JP JP2021553031A patent/JP7734586B2/ja active Active
- 2020-03-09 AU AU2020232026A patent/AU2020232026B2/en active Active
- 2020-03-09 WO PCT/US2020/021726 patent/WO2020181283A1/en not_active Ceased
- 2020-03-09 EP EP20715647.2A patent/EP3935049A1/en active Pending
- 2020-03-09 US US16/813,192 patent/US11033547B2/en active Active
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2021
- 2021-04-30 US US17/245,423 patent/US11696916B2/en active Active
- 2021-09-02 IL IL286077A patent/IL286077A/en unknown