JP2022521800A - 皮膚がんを治療するためのｐｄ－１阻害剤の投与 - Google Patents

皮膚がんを治療するためのｐｄ－１阻害剤の投与 Download PDF

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JP2022521800A
JP2022521800A JP2021550167A JP2021550167A JP2022521800A JP 2022521800 A JP2022521800 A JP 2022521800A JP 2021550167 A JP2021550167 A JP 2021550167A JP 2021550167 A JP2021550167 A JP 2021550167A JP 2022521800 A JP2022521800 A JP 2022521800A
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seq
inhibitor
amino acid
acid sequence
antibody
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JP2021550167A
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Japanese (ja)
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マシュー・ジー・フュリー
イザレル・ロウィ
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2021550167A 2019-02-28 2020-02-27 皮膚がんを治療するためのｐｄ－１阻害剤の投与 Pending JP2022521800A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024225122A JP2025041768A (ja) 2019-02-28 2024-12-20 皮膚がんを治療するためのｐｄ－１阻害剤の投与

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962811827P 2019-02-28 2019-02-28
US62/811,827 2019-02-28
PCT/US2020/020018 WO2020176699A1 (en) 2019-02-28 2020-02-27 Administration of pd-1 inhibitors for treating skin cancer

Related Child Applications (1)

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JP2024225122A Division JP2025041768A (ja) 2019-02-28 2024-12-20 皮膚がんを治療するためのｐｄ－１阻害剤の投与

Publications (1)

Publication Number Publication Date
JP2022521800A true JP2022521800A (ja) 2022-04-12

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ID=70057261

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021550167A Pending JP2022521800A (ja) 2019-02-28 2020-02-27 皮膚がんを治療するためのｐｄ－１阻害剤の投与
JP2024225122A Pending JP2025041768A (ja) 2019-02-28 2024-12-20 皮膚がんを治療するためのｐｄ－１阻害剤の投与

Family Applications After (1)

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JP2024225122A Pending JP2025041768A (ja) 2019-02-28 2024-12-20 皮膚がんを治療するためのｐｄ－１阻害剤の投与

Country Status (12)

Country Link
US (1) US20220259313A1 (https=)
EP (1) EP3930848A1 (https=)
JP (2) JP2022521800A (https=)
KR (1) KR20210134690A (https=)
CN (1) CN113490529A (https=)
AU (1) AU2020228296B2 (https=)
CA (1) CA3137361A1 (https=)
IL (1) IL285050A (https=)
MA (1) MA55084A (https=)
MX (1) MX2021010228A (https=)
SG (1) SG11202108089SA (https=)
WO (1) WO2020176699A1 (https=)

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Publication number Priority date Publication date Assignee Title
TWI680138B (zh) * 2014-01-23 2019-12-21 美商再生元醫藥公司 抗ｐｄ-ｌ１之人類抗體
JP7126941B2 (ja) 2015-12-22 2022-08-29 リジェネロン・ファーマシューティカルズ・インコーポレイテッド がんを治療するための抗ｐｄ－１抗体と二重特異性抗ｃｄ２０／抗ｃｄ３抗体の組合せ
US12516382B2 (en) 2018-12-07 2026-01-06 Arizona Board Of Regents On Behalf Of The University Of Arizona Method of determining risk for skin cancer development and skin cancer therapeutic prevention by measuring PD-1/PD-L1 signaling pathway members
KR20230141869A (ko) * 2021-02-11 2023-10-10 리제너론 파마슈티칼스 인코포레이티드 신보조 요법으로서 pd-1 저해제의 투여에 의한 암 치료 방법
WO2024186917A2 (en) * 2023-03-06 2024-09-12 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions for pd-l1 inhibition and methods of use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017197263A1 (en) * 2016-05-13 2017-11-16 Regeneron Pharmaceuticals, Inc. Methods of treating skin cancer by administering a pd-1 inhibitor
WO2018156494A1 (en) * 2017-02-21 2018-08-30 Regeneron Pharmaceuticals, Inc. Anti-pd-1 antibodies for treatment of lung cancer

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EP1210428B1 (en) 1999-08-23 2015-03-18 Dana-Farber Cancer Institute, Inc. Pd-1, a receptor for b7-4, and uses therefor
ES2350687T3 (es) 2002-07-03 2011-01-26 Ono Pharmaceutical Co., Ltd. Composiciones de inmunopotenciación.
CN1753912B (zh) 2002-12-23 2011-11-02 惠氏公司 抗pd-1抗体及其用途
RU2494107C2 (ru) 2005-05-09 2013-09-27 Оно Фармасьютикал Ко., Лтд. Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
CN104356236B (zh) 2005-07-01 2020-07-03 E.R.施贵宝&圣斯有限责任公司 抗程序性死亡配体1(pd-l1)的人单克隆抗体
HRP20131167T1 (hr) 2007-06-18 2014-01-03 Merck Sharp & Dohme B.V. Antitijela za humani receptor programirane smrti pd-1
WO2009114335A2 (en) 2008-03-12 2009-09-17 Merck & Co., Inc. Pd-1 binding proteins
CN102203132A (zh) 2008-08-25 2011-09-28 安普利穆尼股份有限公司 Pd-1拮抗剂的组合物和使用方法
KR101814408B1 (ko) 2008-09-26 2018-01-04 다나-파버 캔서 인스티튜트 인크. 인간 항-ｐｄ-１, ｐｄ-ｌ１, 및 ｐｄ-ｌ2 항체 및 그의 용도
AU2009333580B2 (en) 2008-12-09 2016-07-07 Genentech, Inc. Anti-PD-L1 antibodies and their use to enhance T-cell function
JP6240600B2 (ja) 2011-07-24 2017-11-29 キュアテク リミテッド ヒト化免疫モノクローナル抗体の変異体
HRP20201595T1 (hr) 2011-11-28 2020-12-11 Merck Patent Gmbh Anti-pd-l1 protutijela i njihova uporaba
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CN109310677A (zh) 2016-04-07 2019-02-05 凯莫森特里克斯股份有限公司 通过联合施用ccr1拮抗剂与pd-1抑制剂或pd-l1拮抗剂降低肿瘤负荷
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WO2017197263A1 (en) * 2016-05-13 2017-11-16 Regeneron Pharmaceuticals, Inc. Methods of treating skin cancer by administering a pd-1 inhibitor
WO2018156494A1 (en) * 2017-02-21 2018-08-30 Regeneron Pharmaceuticals, Inc. Anti-pd-1 antibodies for treatment of lung cancer

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Publication number Publication date
EP3930848A1 (en) 2022-01-05
WO2020176699A1 (en) 2020-09-03
JP2025041768A (ja) 2025-03-26
SG11202108089SA (en) 2021-08-30
AU2020228296A1 (en) 2021-10-14
IL285050A (en) 2021-09-30
US20220259313A1 (en) 2022-08-18
KR20210134690A (ko) 2021-11-10
CA3137361A1 (en) 2020-09-03
CN113490529A (zh) 2021-10-08
MA55084A (fr) 2022-01-05
AU2020228296B2 (en) 2025-10-02
MX2021010228A (es) 2021-10-26

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