|
GB9720465D0
(en)
|
1997-09-25 |
1997-11-26 |
Oxford Biomedica Ltd |
Dual-virus vectors
|
|
US6436392B1
(en)
|
1998-05-20 |
2002-08-20 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors
|
|
EP1224313A1
(en)
|
1999-10-07 |
2002-07-24 |
University of Iowa Research Foundation |
Adeno-associated viruses and uses thereof
|
|
WO2001029243A1
(en)
|
1999-10-15 |
2001-04-26 |
Dalhousie University |
Method and vector for producing and transferring trans-spliced peptides
|
|
US20040072154A1
(en)
*
|
2000-12-22 |
2004-04-15 |
Morris David W. |
Novel compositions and methods for cancer
|
|
JP2003088388A
(ja)
*
|
2001-09-14 |
2003-03-25 |
Herikkusu Kenkyusho:Kk |
新規な全長ｃＤＮＡ
|
|
US20060024278A1
(en)
*
|
2004-01-23 |
2006-02-02 |
The General Hospital Corporation |
Methods and products related to the production of inner ear hair cells
|
|
US20070161031A1
(en)
*
|
2005-12-16 |
2007-07-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Functional arrays for high throughput characterization of gene expression regulatory elements
|
|
US8298818B2
(en)
|
2006-04-28 |
2012-10-30 |
University Of Florida Research Foundation, Inc. |
Self-complementary adeno-associated virus having a truncated CMV-chicken β-actin promoter
|
|
JP5575486B2
(ja)
|
2007-01-18 |
2014-08-20 |
ユニヴァーシティ オブ ミズーリー−コロンビア |
筋鞘にｎＮＯＳを回復させる合成ミニ／ミクロジストロフィン遺伝子
|
|
FR2919305B1
(fr)
|
2007-07-26 |
2009-09-18 |
Genethon Ass Loi De 1901 |
Vecteurs viraux adeno-associes pour l'expression de la dysferline.
|
|
EP2732819B1
(en)
|
2008-02-07 |
2019-10-16 |
Massachusetts Eye & Ear Infirmary |
Compounds that enhance Atoh-1 expression
|
|
US8236557B2
(en)
|
2008-05-28 |
2012-08-07 |
University Of Missouri-Columbia |
Hybrid-AAV vectors to deliver large gene expression cassette
|
|
US8962314B2
(en)
|
2008-11-26 |
2015-02-24 |
The Regents Of The University Of California |
Lateral ventricle cell compositions and use for treating neural degenerative diseases
|
|
HRP20190144T1
(hr)
|
2010-04-23 |
2019-03-22 |
University Of Florida Research Foundation, Inc. |
Pripravci raav-gvanilat ciklaze i postupci za liječenje leberove urođene amauroze-1 (lca1)
|
|
WO2013075008A1
(en)
|
2011-11-16 |
2013-05-23 |
University Of Florida Research Foundation Inc. |
Aav dual vector systems for gene therapy
|
|
EP2802657B1
(en)
*
|
2012-01-12 |
2018-05-02 |
Quark Pharmaceuticals, Inc. |
Combination therapy for treating hearing and balance disorders
|
|
US20150050354A1
(en)
*
|
2012-04-02 |
2015-02-19 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the treatment of otic diseases and conditions
|
|
AU2013249202B2
(en)
|
2012-04-18 |
2018-08-09 |
The Children's Hospital Of Philadelphia |
Composition and methods for highly efficient gene transfer using AAV capsid variants
|
|
CA2884309A1
(en)
*
|
2012-09-07 |
2014-03-13 |
Massachusetts Eye And Ear Infirmary |
Methods and compositions for regenerating hair cells and/or supporting cells from differentiated cochlear cells or differentiated utricular cells by modulation of notch and cmyc activity
|
|
CA2909733C
(en)
|
2013-04-18 |
2023-10-17 |
Fondazione Telethon |
Effective delivery of large genes by dual aav vectors
|
|
KR102234672B1
(ko)
|
2013-05-21 |
2021-04-06 |
유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 |
캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
|
|
US10751385B2
(en)
|
2015-02-20 |
2020-08-25 |
Institut Pasteur |
Prevention and/or treatment of hearing loss or impairment
|
|
RS63416B1
(sr)
|
2015-03-03 |
2022-08-31 |
Fond Telethon |
Sistem višestrukih vektora i njegove primene
|
|
SG11201804814YA
(en)
|
2015-12-11 |
2018-07-30 |
Massachusetts Eye & Ear Infirmary |
Materials and methods for delivering nucleic acids to cochlear and vestibular cells
|
|
WO2017108931A1
(en)
|
2015-12-22 |
2017-06-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Improved hybrid dual recombinant aav vector systems for gene therapy
|
|
JP2019530737A
(ja)
|
2016-08-23 |
2019-10-24 |
アコーオス インコーポレイテッド |
ヒト対象において非加齢性聴力障害を治療するための組成物および方法
|
|
WO2018145111A1
(en)
|
2017-02-06 |
2018-08-09 |
Children's Medical Center Corporation |
Materials and methods for delivering nucleic acids to cochlear and vestibular cells
|
|
AU2018261769B2
(en)
|
2017-05-05 |
2024-03-14 |
The Regents Of The University Of California |
Compositions and methods for expressing Otoferlin
|
|
DE102018103924A1
(de)
|
2018-02-21 |
2019-08-22 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Gentherapeutische Behandlung von Schwerhörigkeit
|
|
IL325122A
(en)
|
2018-02-22 |
2026-02-01 |
Akouos Inc |
Compositions and methods for treating non-age-related hearing impairment in humans
|
|
CN119410636A
(zh)
*
|
2018-04-27 |
2025-02-11 |
分贝治疗公司 |
肌球蛋白15启动子及其用途
|
|
US11660353B2
(en)
*
|
2018-04-27 |
2023-05-30 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
|
US12188041B2
(en)
|
2018-11-01 |
2025-01-07 |
University Of Florida Research Foundation, Incorporated |
Codon optimized otoferlin AAV dual vector gene therapy
|
|
CN118497276A
(zh)
|
2018-11-07 |
2024-08-16 |
阿库斯股份有限公司 |
腺相关病毒载体用于在内耳中的毛细胞和支持细胞中校正基因缺陷/表达蛋白质的用途
|
|
WO2020148458A1
(en)
|
2019-01-18 |
2020-07-23 |
Institut Pasteur |
Aav-mediated gene therapy restoring the otoferlin gene
|
|
JP2022522995A
(ja)
|
2019-01-18 |
2022-04-21 |
ボイジャー セラピューティクス インコーポレイテッド |
Ａａｖ粒子を生成するための方法及びシステム
|
|
EP3921032A4
(en)
|
2019-02-08 |
2022-11-30 |
Decibel Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS
|
|
CA3159549A1
(en)
|
2019-10-30 |
2021-05-06 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
|
CN117295529A
(zh)
|
2021-02-19 |
2023-12-26 |
分贝治疗公司 |
使用耳畸蛋白双载体系统治疗感觉神经性听力损失的方法
|
|
EP4665751A2
(en)
|
2023-02-17 |
2025-12-24 |
Decibel Therapeutics, Inc. |
Methods and compositions for administering otoferlin dual vector systems
|