JP2022516004A5 - - Google Patents
Info
- Publication number
- JP2022516004A5 JP2022516004A5 JP2021535829A JP2021535829A JP2022516004A5 JP 2022516004 A5 JP2022516004 A5 JP 2022516004A5 JP 2021535829 A JP2021535829 A JP 2021535829A JP 2021535829 A JP2021535829 A JP 2021535829A JP 2022516004 A5 JP2022516004 A5 JP 2022516004A5
- Authority
- JP
- Japan
- Prior art keywords
- promoter
- gene
- nucleic acid
- desuppressable
- mammalian cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025039219A JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783589P | 2018-12-21 | 2018-12-21 | |
| US62/783,589 | 2018-12-21 | ||
| US201962866092P | 2019-06-25 | 2019-06-25 | |
| US62/866,092 | 2019-06-25 | ||
| PCT/US2019/067156 WO2020132059A1 (en) | 2018-12-21 | 2019-12-18 | Adeno-associated virus (aav) producer cell line and related methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025039219A Division JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022516004A JP2022516004A (ja) | 2022-02-24 |
| JP2022516004A5 true JP2022516004A5 (enExample) | 2022-12-26 |
| JP7650800B2 JP7650800B2 (ja) | 2025-03-25 |
Family
ID=71099162
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021535829A Active JP7650800B2 (ja) | 2018-12-21 | 2019-12-18 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
| JP2025039219A Pending JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025039219A Pending JP2025102801A (ja) | 2018-12-21 | 2025-03-12 | アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11739347B2 (enExample) |
| EP (1) | EP3891290A4 (enExample) |
| JP (2) | JP7650800B2 (enExample) |
| KR (1) | KR20210108423A (enExample) |
| CN (1) | CN113396222A (enExample) |
| IL (1) | IL284219A (enExample) |
| SG (1) | SG11202106217TA (enExample) |
| WO (1) | WO2020132059A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12054738B2 (en) | 2020-07-30 | 2024-08-06 | Shape Therapeutics Inc. | Stable cell lines for inducible production of rAAV virions |
| WO2022079083A1 (en) * | 2020-10-15 | 2022-04-21 | F. Hoffmann-La Roche Ag | Nucleic acid constructs for va rna transcription |
| CN112501209B (zh) * | 2020-12-07 | 2024-02-13 | 和元生物技术（上海）股份有限公司 | 外源基因可控表达的腺相关病毒包装方法 |
| JPWO2022172986A1 (enExample) * | 2021-02-12 | 2022-08-18 | ||
| EP4322975A4 (en) * | 2021-04-14 | 2025-03-26 | Capsida, Inc. | PLASMIDS AND PROCESSES FOR PRODUCING ADENO-ASSOCIATED VIRUSES |
| EP4410971A4 (en) * | 2021-09-30 | 2025-06-04 | FUJIFILM Corporation | METHOD FOR PRODUCING AN ADENO-ASSOCIATED VIRUS, CELLS AND EXPRESSION VECTOR |
| AR127674A1 (es) | 2021-10-18 | 2024-02-21 | Regeneron Pharma | Células de mamífero que comprenden genes cas9 integrados para producir sitios de integración estables, y células de mamífero que comprenden sitios de integración estables y otros sitios |
| JP2024537896A (ja) * | 2021-10-18 | 2024-10-16 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アデノウイルス随伴ウイルスポリヌクレオチドを含む真核細胞 |
| WO2023150506A2 (en) * | 2022-02-01 | 2023-08-10 | Shape Therapeutics Inc. | STABLE CELL LINES FOR INDUCIBLE PRODUCTION OF rAAV VIRIONS |
| EP4491717A4 (en) * | 2022-03-08 | 2025-11-12 | Fujifilm Corp | PRODUCING CELL, PRODUCTION METHOD FOR PRODUCING PRODUCING CELLS AND PRODUCTION METHOD FOR ADENE-ASSOCIATED VIRUS |
| EP4578943A4 (en) * | 2022-08-25 | 2026-02-25 | Fujifilm Corp | PROCESS FOR TARGETING VIRUS PRODUCTION AND CULTURE COMPOSITION |
| WO2024143429A1 (ja) * | 2022-12-27 | 2024-07-04 | 株式会社シンプロジェン | ヘルパー遺伝子制御 |
| US12410436B2 (en) * | 2023-10-31 | 2025-09-09 | Lonza Houston, Inc. | Adeno-associated virus (AAV) producer cell lines |
| WO2025122676A1 (en) * | 2023-12-05 | 2025-06-12 | Shape Therapeutics Inc. | Systems and methods for raav production using a biphasic culture |
| AU2025218748A1 (en) | 2024-02-09 | 2026-08-06 | F. Hoffmann-La Roche Ag | Method for producing recombinant adeno-associated viral particles |
| WO2025252480A1 (en) | 2024-06-07 | 2025-12-11 | F. Hoffmann-La Roche Ag | Method for purifying plasmid dna |
| CN118460545B (zh) * | 2024-07-08 | 2025-02-11 | 凌意(杭州)生物科技有限公司 | 一种诱导型表达Rep多肽的表达框 |
| US20260022401A1 (en) | 2024-07-22 | 2026-01-22 | Hoffmann-La Roche Inc. | Novel AAV rep ORFs and Rep polypeptides |
| WO2026037757A1 (en) | 2024-08-13 | 2026-02-19 | F. Hoffmann-La Roche Ag | Modified aav particles |
| WO2026044087A1 (en) * | 2024-08-21 | 2026-02-26 | Shape Therapeutics Inc. | Increased cellular stability for aav production |
| WO2026132012A1 (en) | 2024-12-20 | 2026-06-25 | F. Hoffmann-La Roche Ag | Aav particle processing using affinity chromatography with gradient elution |
| WO2026132139A1 (en) | 2024-12-20 | 2026-06-25 | F. Hoffmann-La Roche Ag | Purification process for viral vectors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622856A (en) | 1995-08-03 | 1997-04-22 | Avigen | High efficiency helper system for AAV vector production |
| US6037177A (en) * | 1997-08-08 | 2000-03-14 | Cell Genesys, Inc. | Method for increasing the efficiency of recombinant AAV production |
| JP2002153278A (ja) * | 2000-11-22 | 2002-05-28 | Hisamitsu Pharmaceut Co Inc | ウイルスベクターの製造に用いられる細胞、その製法およびその細胞を用いたウイルスベクターの製造方法 |
| US8067156B2 (en) * | 2001-05-31 | 2011-11-29 | The Rockefeller University | Method for generating replication defective viral vectors that are helper free |
| AU2002367943A1 (en) * | 2001-12-18 | 2003-12-22 | University Of North Carolina At Chapel Hill | Improved reagents and methods for producing parvoviruses |
| CA2596588C (en) | 2005-01-31 | 2017-06-27 | University Of Iowa Research Foundation | Nucleic acid silencing of huntington's disease gene |
| WO2011126808A2 (en) * | 2010-03-29 | 2011-10-13 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
| JP6661544B2 (ja) | 2014-04-24 | 2020-03-11 | ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 遺伝子改変したｔ細胞の自動生成法 |
| MX2017011915A (es) * | 2015-03-16 | 2018-05-22 | Board Of Trustees Southern Illinois Univ | Sistema para la expresion genica estable. |
| EP3571294A1 (en) | 2017-01-18 | 2019-11-27 | F1 Oncology, Inc. | Methods of transducing and expanding immune cells and uses thereof |
| BR112019021595A2 (pt) | 2017-04-18 | 2020-05-12 | Glaxosmithkline Intellectual Property Development Limited | Célula produtora de vírus adeno-associado, vetor de ácido nucleico, métodos para produzir uma linhagem de células de empacotamento estável de vírus adeno-associado e uma partícula de vetor de vírus adeno-associado com defeito de replicação, célula de empacotamento de vírus adeno-associado, e, partícula de vetor de vírus adeno-associado com defeito de replicação. |
-
2019
- 2019-12-18 SG SG11202106217TA patent/SG11202106217TA/en unknown
- 2019-12-18 CN CN201980090045.3A patent/CN113396222A/zh active Pending
- 2019-12-18 WO PCT/US2019/067156 patent/WO2020132059A1/en not_active Ceased
- 2019-12-18 US US16/719,251 patent/US11739347B2/en active Active
- 2019-12-18 JP JP2021535829A patent/JP7650800B2/ja active Active
- 2019-12-18 KR KR1020217022728A patent/KR20210108423A/ko active Pending
- 2019-12-18 EP EP19899841.1A patent/EP3891290A4/en active Pending
-
2021
- 2021-06-20 IL IL284219A patent/IL284219A/en unknown
-
2023
- 2023-07-14 US US18/352,657 patent/US12529074B2/en active Active
-
2025
- 2025-03-12 JP JP2025039219A patent/JP2025102801A/ja active Pending
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