JP2022516004A5 - - Google Patents

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Publication number
JP2022516004A5
JP2022516004A5 JP2021535829A JP2021535829A JP2022516004A5 JP 2022516004 A5 JP2022516004 A5 JP 2022516004A5 JP 2021535829 A JP2021535829 A JP 2021535829A JP 2021535829 A JP2021535829 A JP 2021535829A JP 2022516004 A5 JP2022516004 A5 JP 2022516004A5
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JP
Japan
Prior art keywords
promoter
gene
nucleic acid
desuppressable
mammalian cell
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JP2021535829A
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English (en)
Japanese (ja)
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JP2022516004A (ja
JP7650800B2 (ja
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Priority claimed from PCT/US2019/067156 external-priority patent/WO2020132059A1/en
Publication of JP2022516004A publication Critical patent/JP2022516004A/ja
Publication of JP2022516004A5 publication Critical patent/JP2022516004A5/ja
Priority to JP2025039219A priority Critical patent/JP2025102801A/ja
Application granted granted Critical
Publication of JP7650800B2 publication Critical patent/JP7650800B2/ja
Active legal-status Critical Current
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JP2021535829A 2018-12-21 2019-12-18 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 Active JP7650800B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025039219A JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862783589P 2018-12-21 2018-12-21
US62/783,589 2018-12-21
US201962866092P 2019-06-25 2019-06-25
US62/866,092 2019-06-25
PCT/US2019/067156 WO2020132059A1 (en) 2018-12-21 2019-12-18 Adeno-associated virus (aav) producer cell line and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025039219A Division JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Publications (3)

Publication Number Publication Date
JP2022516004A JP2022516004A (ja) 2022-02-24
JP2022516004A5 true JP2022516004A5 (enExample) 2022-12-26
JP7650800B2 JP7650800B2 (ja) 2025-03-25

Family

ID=71099162

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021535829A Active JP7650800B2 (ja) 2018-12-21 2019-12-18 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法
JP2025039219A Pending JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Family Applications After (1)

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JP2025039219A Pending JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Country Status (8)

Country Link
US (2) US11739347B2 (enExample)
EP (1) EP3891290A4 (enExample)
JP (2) JP7650800B2 (enExample)
KR (1) KR20210108423A (enExample)
CN (1) CN113396222A (enExample)
IL (1) IL284219A (enExample)
SG (1) SG11202106217TA (enExample)
WO (1) WO2020132059A1 (enExample)

Families Citing this family (19)

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Publication number Priority date Publication date Assignee Title
JP2023536148A (ja) * 2020-07-30 2023-08-23 シェイプ セラピューティクス インク． Ｒａａｖウイルス粒子の誘導産生のための安定な細胞株
KR20230085929A (ko) 2020-10-15 2023-06-14 에프. 호프만-라 로슈 아게 Va rna 전사를 위한 핵산 구조체
CN112501209B (zh) * 2020-12-07 2024-02-13 和元生物技术（上海）股份有限公司 外源基因可控表达的腺相关病毒包装方法
EP4293118A4 (en) 2021-02-12 2025-01-22 FUJIFILM Corporation KIT FOR THE PRODUCTION OF ADENO-ASSOCIATED VIRUS AND USE OF THE KIT
WO2022221397A2 (en) * 2021-04-14 2022-10-20 Capsida, Inc. Plasmids and methods of production of adeno-associated viruses
WO2023054671A1 (ja) * 2021-09-30 2023-04-06 富士フイルム株式会社 アデノ随伴ウイルスの製造方法、細胞および発現ベクター
US12234472B2 (en) * 2021-10-18 2025-02-25 Regeneron Pharmaceuticals, Inc. Eukaryotic cells comprising adenovirus-associated virus polynucleotides
EP4473123A4 (en) * 2022-02-01 2026-03-11 Shape Therapeutics Inc STABLE CELL LINES FOR INDUCIBLE VAAR VIRION PRODUCTION
JPWO2023171698A1 (enExample) 2022-03-08 2023-09-14
JPWO2024043322A1 (enExample) * 2022-08-25 2024-02-29
EP4624584A1 (en) * 2022-12-27 2025-10-01 Synplogen Co., Ltd. Helper gene control
US12410436B2 (en) * 2023-10-31 2025-09-09 Lonza Houston, Inc. Adeno-associated virus (AAV) producer cell lines
WO2025122676A1 (en) * 2023-12-05 2025-06-12 Shape Therapeutics Inc. Systems and methods for raav production using a biphasic culture
WO2025168663A1 (en) 2024-02-09 2025-08-14 F. Hoffmann-La Roche Ag Method for producing recombinant adeno-associated viral particles
WO2025252480A1 (en) 2024-06-07 2025-12-11 F. Hoffmann-La Roche Ag Method for purifying plasmid dna
CN118460545B (zh) * 2024-07-08 2025-02-11 凌意(杭州)生物科技有限公司 一种诱导型表达Rep多肽的表达框
WO2026022064A1 (en) 2024-07-22 2026-01-29 F. Hoffmann-La Roche Ag Novel aav rep orfs and rep polypeptides
WO2026037757A1 (en) 2024-08-13 2026-02-19 F. Hoffmann-La Roche Ag Modified aav particles
WO2026044087A1 (en) * 2024-08-21 2026-02-26 Shape Therapeutics Inc. Increased cellular stability for aav production

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622856A (en) 1995-08-03 1997-04-22 Avigen High efficiency helper system for AAV vector production
US6037177A (en) * 1997-08-08 2000-03-14 Cell Genesys, Inc. Method for increasing the efficiency of recombinant AAV production
JP2002153278A (ja) * 2000-11-22 2002-05-28 Hisamitsu Pharmaceut Co Inc ウイルスベクターの製造に用いられる細胞、その製法およびその細胞を用いたウイルスベクターの製造方法
WO2002097056A2 (en) * 2001-05-31 2002-12-05 The Rockefeller University Method for generating replication defective viral vectors that are helper free
AU2002367943A1 (en) * 2001-12-18 2003-12-22 University Of North Carolina At Chapel Hill Improved reagents and methods for producing parvoviruses
WO2006083800A2 (en) 2005-01-31 2006-08-10 University Of Iowa Research Foundation Nucleic acid silencing of huntington's disease gene
KR20130040844A (ko) * 2010-03-29 2013-04-24 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 약학적으로 유발된 전이유전자 제거 시스템
WO2015162211A1 (en) 2014-04-24 2015-10-29 Miltenyi Biotec Gmbh Method for automated generation of genetically modified t cells
JP2018508223A (ja) * 2015-03-16 2018-03-29 ボード・オブ・トラスティーズ、サザン・イリノイ・ユニバーシティ 安定な遺伝子発現のための系
WO2018136566A1 (en) 2017-01-18 2018-07-26 F1 Oncology, Inc. Methods of transducing and expanding immune cells and uses thereof
CN110785495A (zh) 2017-04-18 2020-02-11 葛兰素史克知识产权开发有限公司 腺相关病毒载体的生产方法

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