JP2022516004A5 - - Google Patents

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Publication number
JP2022516004A5
JP2022516004A5 JP2021535829A JP2021535829A JP2022516004A5 JP 2022516004 A5 JP2022516004 A5 JP 2022516004A5 JP 2021535829 A JP2021535829 A JP 2021535829A JP 2021535829 A JP2021535829 A JP 2021535829A JP 2022516004 A5 JP2022516004 A5 JP 2022516004A5
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JP
Japan
Prior art keywords
promoter
gene
nucleic acid
desuppressable
mammalian cell
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JP2021535829A
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English (en)
Japanese (ja)
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JP7650800B2 (ja
JP2022516004A (ja
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Priority claimed from PCT/US2019/067156 external-priority patent/WO2020132059A1/en
Publication of JP2022516004A publication Critical patent/JP2022516004A/ja
Publication of JP2022516004A5 publication Critical patent/JP2022516004A5/ja
Priority to JP2025039219A priority Critical patent/JP2025102801A/ja
Application granted granted Critical
Publication of JP7650800B2 publication Critical patent/JP7650800B2/ja
Active legal-status Critical Current
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JP2021535829A 2018-12-21 2019-12-18 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法 Active JP7650800B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025039219A JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862783589P 2018-12-21 2018-12-21
US62/783,589 2018-12-21
US201962866092P 2019-06-25 2019-06-25
US62/866,092 2019-06-25
PCT/US2019/067156 WO2020132059A1 (en) 2018-12-21 2019-12-18 Adeno-associated virus (aav) producer cell line and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025039219A Division JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Publications (3)

Publication Number Publication Date
JP2022516004A JP2022516004A (ja) 2022-02-24
JP2022516004A5 true JP2022516004A5 (enExample) 2022-12-26
JP7650800B2 JP7650800B2 (ja) 2025-03-25

Family

ID=71099162

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021535829A Active JP7650800B2 (ja) 2018-12-21 2019-12-18 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法
JP2025039219A Pending JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Family Applications After (1)

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JP2025039219A Pending JP2025102801A (ja) 2018-12-21 2025-03-12 アデノ随伴ウイルス（ａａｖ）産生細胞株および関連方法

Country Status (8)

Country Link
US (2) US11739347B2 (enExample)
EP (1) EP3891290A4 (enExample)
JP (2) JP7650800B2 (enExample)
KR (1) KR20210108423A (enExample)
CN (1) CN113396222A (enExample)
IL (1) IL284219A (enExample)
SG (1) SG11202106217TA (enExample)
WO (1) WO2020132059A1 (enExample)

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US12054738B2 (en) 2020-07-30 2024-08-06 Shape Therapeutics Inc. Stable cell lines for inducible production of rAAV virions
CA3197730A1 (en) * 2020-10-15 2022-04-21 F. Hoffman-La Roche Ag Nucleic acid constructs for va rna transcription
CN112501209B (zh) * 2020-12-07 2024-02-13 和元生物技术（上海）股份有限公司 外源基因可控表达的腺相关病毒包装方法
CN116829725A (zh) * 2021-02-12 2023-09-29 富士胶片株式会社 用于产生腺相关病毒的试剂盒及其利用
EP4322975A4 (en) * 2021-04-14 2025-03-26 Capsida, Inc. PLASMIDS AND PROCESSES FOR PRODUCING ADENO-ASSOCIATED VIRUSES
EP4410971A4 (en) * 2021-09-30 2025-06-04 FUJIFILM Corporation METHOD FOR PRODUCING AN ADENO-ASSOCIATED VIRUS, CELLS AND EXPRESSION VECTOR
TW202323529A (zh) * 2021-10-18 2023-06-16 美商再生元醫藥公司 包括腺病毒相關病毒聚核苷酸的真核細胞
EP4473123A4 (en) * 2022-02-01 2026-03-11 Shape Therapeutics Inc STABLE CELL LINES FOR INDUCIBLE VAAR VIRION PRODUCTION
JPWO2023171698A1 (enExample) * 2022-03-08 2023-09-14
CN120092093A (zh) * 2022-08-25 2025-06-03 富士胶片株式会社 靶病毒的制造方法及培养组合物
WO2024143429A1 (ja) * 2022-12-27 2024-07-04 株式会社シンプロジェン ヘルパー遺伝子制御
US12410436B2 (en) * 2023-10-31 2025-09-09 Lonza Houston, Inc. Adeno-associated virus (AAV) producer cell lines
WO2025122676A1 (en) * 2023-12-05 2025-06-12 Shape Therapeutics Inc. Systems and methods for raav production using a biphasic culture
WO2025168663A1 (en) 2024-02-09 2025-08-14 F. Hoffmann-La Roche Ag Method for producing recombinant adeno-associated viral particles
WO2025252480A1 (en) 2024-06-07 2025-12-11 F. Hoffmann-La Roche Ag Method for purifying plasmid dna
CN118460545B (zh) * 2024-07-08 2025-02-11 凌意(杭州)生物科技有限公司 一种诱导型表达Rep多肽的表达框
WO2026022064A1 (en) 2024-07-22 2026-01-29 F. Hoffmann-La Roche Ag Novel aav rep orfs and rep polypeptides
WO2026037757A1 (en) 2024-08-13 2026-02-19 F. Hoffmann-La Roche Ag Modified aav particles
WO2026044087A1 (en) * 2024-08-21 2026-02-26 Shape Therapeutics Inc. Increased cellular stability for aav production

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622856A (en) 1995-08-03 1997-04-22 Avigen High efficiency helper system for AAV vector production
US6037177A (en) * 1997-08-08 2000-03-14 Cell Genesys, Inc. Method for increasing the efficiency of recombinant AAV production
JP2002153278A (ja) * 2000-11-22 2002-05-28 Hisamitsu Pharmaceut Co Inc ウイルスベクターの製造に用いられる細胞、その製法およびその細胞を用いたウイルスベクターの製造方法
US8067156B2 (en) * 2001-05-31 2011-11-29 The Rockefeller University Method for generating replication defective viral vectors that are helper free
AU2002367943A1 (en) * 2001-12-18 2003-12-22 University Of North Carolina At Chapel Hill Improved reagents and methods for producing parvoviruses
EP1844148A2 (en) 2005-01-31 2007-10-17 University of Iowa Research Foundation Nucleic acid silencing of huntington's disease gene
WO2011126808A2 (en) * 2010-03-29 2011-10-13 The Trustees Of The University Of Pennsylvania Pharmacologically induced transgene ablation system
CN106062185A (zh) 2014-04-24 2016-10-26 美天旎生物技术有限公司 用于自动生成遗传修饰的t细胞的方法
EP3271462A4 (en) * 2015-03-16 2018-08-29 Board of Trustees, Southern Illinois University System for stable gene expression
US20190367876A1 (en) 2017-01-18 2019-12-05 F1 Oncology, Inc. Methods of transducing and expanding immune cells and uses thereof
EP3612635A2 (en) 2017-04-18 2020-02-26 GlaxoSmithKline Intellectual Property Development Limited Methods for adeno-associated viral vector production

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