JP2022511209A5 - - Google Patents
Info
- Publication number
- JP2022511209A5 JP2022511209A5 JP2020572856A JP2020572856A JP2022511209A5 JP 2022511209 A5 JP2022511209 A5 JP 2022511209A5 JP 2020572856 A JP2020572856 A JP 2020572856A JP 2020572856 A JP2020572856 A JP 2020572856A JP 2022511209 A5 JP2022511209 A5 JP 2022511209A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- methyl
- pyridine
- urea
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862694373P | 2018-07-05 | 2018-07-05 | |
| US62/694,373 | 2018-07-05 | ||
| PCT/US2019/040595 WO2020010252A1 (en) | 2018-07-05 | 2019-07-03 | Fused ring compound having urea structure |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022511209A JP2022511209A (ja) | 2022-01-31 |
| JP2022511209A5 true JP2022511209A5 (enExample) | 2022-07-05 |
| JP7399122B2 JP7399122B2 (ja) | 2023-12-15 |
Family
ID=67480298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020572856A Active JP7399122B2 (ja) | 2018-07-05 | 2019-07-03 | ウレア構造を有する縮合環化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11918568B2 (enExample) |
| EP (1) | EP3818053B1 (enExample) |
| JP (1) | JP7399122B2 (enExample) |
| CN (1) | CN112654608B (enExample) |
| AU (1) | AU2019297453B2 (enExample) |
| CA (1) | CA3105456A1 (enExample) |
| TW (1) | TWI812746B (enExample) |
| WO (1) | WO2020010252A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3818053B1 (en) | 2018-07-05 | 2023-03-29 | Sanford Burnham Prebys Medical Discovery Institute | Fused ring compound having urea structure |
| CA3166358A1 (en) * | 2020-02-12 | 2021-08-19 | Monali BANERJEE | Small molecule sting antagonists |
| WO2021207343A1 (en) * | 2020-04-08 | 2021-10-14 | Rheos Medicines, Inc. | Malt1 inhibitors and uses thereof |
| CN113372276B (zh) * | 2021-05-25 | 2022-04-22 | 三峡大学 | 吲唑类衍生物及其应用 |
| CN113666862B (zh) * | 2021-08-18 | 2024-05-31 | 山东大学 | 一种通过镍催化不对称硝化反应制备手性3-硝基吲哚类化合物的方法 |
| AU2023347120A1 (en) * | 2022-09-23 | 2025-03-06 | Sironax Ltd. | Nampt modulators, preparations, and uses thereof |
| AU2024218066A1 (en) * | 2023-02-10 | 2025-07-31 | Samjin Pharmaceutical Co., Ltd. | New compound and pharmaceutical composition comprising same |
| KR20260023474A (ko) * | 2024-08-09 | 2026-02-20 | 삼진제약주식회사 | Nampt 억제제 및 이를 포함하는 항체-약물 접합체 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3128280A (en) | 1959-10-23 | 1964-04-07 | Searle & Co | 1-(alkoxylated/halogenated phenyl)-3-pyridylmethylureas |
| US4001256A (en) | 1973-12-26 | 1977-01-04 | The Upjohn Company | Pyridylalkyl phenyl ureas and their n-oxides |
| WO1997024343A1 (en) | 1995-12-29 | 1997-07-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | Phenyl thiazole derivatives with anti herpes virus properties |
| TWI334868B (en) | 2003-06-03 | 2010-12-21 | Nippon Kayaku Kk | [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof |
| US7700592B2 (en) | 2005-08-25 | 2010-04-20 | Schering Corporation | α2C adrenoreceptor agonists |
| WO2007069565A1 (ja) | 2005-12-12 | 2007-06-21 | Ono Pharmaceutical Co., Ltd. | 二環式複素環化合物 |
| WO2007086584A1 (ja) * | 2006-01-30 | 2007-08-02 | Meiji Seika Kaisha, Ltd. | 新規ＦａｂＫおよびＦａｂＩ／Ｋ阻害剤 |
| EP2277881A4 (en) * | 2008-04-18 | 2011-09-07 | Shionogi & Co | HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON P13K |
| AU2011223790A1 (en) * | 2010-03-01 | 2012-08-30 | Myrexis, Inc. | Compounds and therapeutic uses thereof |
| US20130317027A1 (en) * | 2010-03-01 | 2013-11-28 | Myrexis, Inc. | Compounds and therapeutic uses thereof |
| CN103270023B (zh) | 2010-09-03 | 2016-11-02 | 福马Tm有限责任公司 | 作为用于治疗疾病诸如癌症的nampt 抑制剂的4-{[(吡啶-3-基-甲基)氨基羰基]氨基}苯-砜衍生物 |
| AR082886A1 (es) | 2010-09-03 | 2013-01-16 | Forma Therapeutics Inc | Compuestos y composiciones farmaceuticas que los contienen |
| CN102670625B (zh) | 2011-03-18 | 2014-05-28 | 中国人民解放军第二军医大学 | 一种脲类化合物的应用 |
| RU2616612C2 (ru) | 2011-05-04 | 2017-04-18 | ФОРМА ТиЭм, ЭлЭлСИ | Новые соединения и композиции для ингибирования nampt |
| EP2727920B1 (en) | 2011-07-29 | 2016-11-02 | FUJIFILM Corporation | 1,5-naphthyridine derivative or salt thereof |
| WO2013047813A1 (ja) | 2011-09-30 | 2013-04-04 | 大鵬薬品工業株式会社 | １，２，４－トリアジン－６－カルボキサミド誘導体 |
| EP2770987B1 (en) | 2011-10-27 | 2018-04-04 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
| WO2014111871A1 (en) | 2013-01-17 | 2014-07-24 | Aurigene Discovery Technologies Limited | 4,5-dihydroisoxazole derivatives as nampt inhibitors |
| CN105408331A (zh) | 2013-06-03 | 2016-03-16 | 拜耳制药股份公司 | 作为用于治疗血栓栓塞病症的凝血酶抑制剂的三唑并吡啶 |
| WO2016198698A2 (en) | 2015-06-12 | 2016-12-15 | Cnic Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | P38 inhibitors for the treatment and prophylaxis of liver cancer |
| EP3568390B1 (en) | 2017-01-10 | 2024-03-06 | Sanford Burnham Prebys Medical Discovery Institute | Small molecule activators of nicotinamide phosphoribosyltransferase (nampt) and uses thereof |
| EP3818053B1 (en) * | 2018-07-05 | 2023-03-29 | Sanford Burnham Prebys Medical Discovery Institute | Fused ring compound having urea structure |
-
2019
- 2019-07-03 EP EP19746226.0A patent/EP3818053B1/en active Active
- 2019-07-03 US US17/257,262 patent/US11918568B2/en active Active
- 2019-07-03 TW TW108123385A patent/TWI812746B/zh active
- 2019-07-03 AU AU2019297453A patent/AU2019297453B2/en active Active
- 2019-07-03 CA CA3105456A patent/CA3105456A1/en active Pending
- 2019-07-03 JP JP2020572856A patent/JP7399122B2/ja active Active
- 2019-07-03 CN CN201980058343.4A patent/CN112654608B/zh active Active
- 2019-07-03 WO PCT/US2019/040595 patent/WO2020010252A1/en not_active Ceased
-
2024
- 2024-01-23 US US18/420,446 patent/US12263159B2/en active Active
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