JP2022507519A5 - - Google Patents

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Publication number
JP2022507519A5
JP2022507519A5 JP2021526521A JP2021526521A JP2022507519A5 JP 2022507519 A5 JP2022507519 A5 JP 2022507519A5 JP 2021526521 A JP2021526521 A JP 2021526521A JP 2021526521 A JP2021526521 A JP 2021526521A JP 2022507519 A5 JP2022507519 A5 JP 2022507519A5
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JP
Japan
Prior art keywords
substituted
group
moiety
tacn
macrocyclic complex
Prior art date
Application number
JP2021526521A
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English (en)
Japanese (ja)
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JPWO2020102820A5 (https=
JP2022507519A (ja
JP7582942B2 (ja
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Priority claimed from PCT/US2019/062077 external-priority patent/WO2020102820A1/en
Publication of JP2022507519A publication Critical patent/JP2022507519A/ja
Publication of JP2022507519A5 publication Critical patent/JP2022507519A5/ja
Publication of JPWO2020102820A5 publication Critical patent/JPWO2020102820A5/ja
Priority to JP2024163405A priority Critical patent/JP2024178308A/ja
Application granted granted Critical
Publication of JP7582942B2 publication Critical patent/JP7582942B2/ja
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JP2021526521A 2018-11-16 2019-11-18 アニオン性ペンダントおよび補助基を含む、鉄（ｉｉｉ）ｍｒｉ造影剤として使用するための化合物 Active JP7582942B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024163405A JP2024178308A (ja) 2018-11-16 2024-09-20 アニオン性ペンダントおよび補助基を含む、鉄（ｉｉｉ）ｍｒｉ造影剤として使用するための化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862768823P 2018-11-16 2018-11-16
US62/768,823 2018-11-16
PCT/US2019/062077 WO2020102820A1 (en) 2018-11-16 2019-11-18 Compounds for use as iron (iii) mri contrast agents containing anionic pendents and ancillary groups

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024163405A Division JP2024178308A (ja) 2018-11-16 2024-09-20 アニオン性ペンダントおよび補助基を含む、鉄（ｉｉｉ）ｍｒｉ造影剤として使用するための化合物

Publications (4)

Publication Number Publication Date
JP2022507519A JP2022507519A (ja) 2022-01-18
JP2022507519A5 true JP2022507519A5 (https=) 2022-09-29
JPWO2020102820A5 JPWO2020102820A5 (https=) 2022-09-29
JP7582942B2 JP7582942B2 (ja) 2024-11-13

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ID=70730921

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021526521A Active JP7582942B2 (ja) 2018-11-16 2019-11-18 アニオン性ペンダントおよび補助基を含む、鉄（ｉｉｉ）ｍｒｉ造影剤として使用するための化合物
JP2024163405A Pending JP2024178308A (ja) 2018-11-16 2024-09-20 アニオン性ペンダントおよび補助基を含む、鉄（ｉｉｉ）ｍｒｉ造影剤として使用するための化合物

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JP2024163405A Pending JP2024178308A (ja) 2018-11-16 2024-09-20 アニオン性ペンダントおよび補助基を含む、鉄（ｉｉｉ）ｍｒｉ造影剤として使用するための化合物

Country Status (7)

Country Link
US (1) US11344635B2 (https=)
EP (1) EP3880257A4 (https=)
JP (2) JP7582942B2 (https=)
KR (1) KR20210114932A (https=)
CN (1) CN113646009A (https=)
AU (1) AU2019381793B2 (https=)
WO (1) WO2020102820A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019381793B2 (en) * 2018-11-16 2025-02-27 The Research Foundation For The State University Of New York Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups
US20240228524A1 (en) * 2021-03-20 2024-07-11 The Research Foundation For The State University Of New York Iron(iii) macrocyclic complexes with mixed hyroxyl pendants as mri contrast agents
WO2024097160A1 (en) * 2022-10-31 2024-05-10 Yale University Transition metal complexes for mri applications and methods of use
CN121698848A (zh) * 2026-02-09 2026-03-20 浙江大学衢州研究院 一种具有三氮杂环壬烷大环骨架的铁配合物及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2091251T3 (es) * 1989-11-27 1996-11-01 Concat Ltd Perfeccionamiento de la imagen en la mri del hueso y del tejido emparentado utilizando complejos de cationes paramagneticos y ligandos polifosfonato.
US5236695A (en) 1989-11-27 1993-08-17 Concat, Ltd. MRI image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands
US5409689A (en) 1993-08-13 1995-04-25 Concat, Ltd. MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms
EP0955044B1 (en) * 1995-06-26 2005-11-16 Chelator LLC Method of inhibiting bacterial or fungal growth using a complexing agent
US6264966B1 (en) 2000-02-22 2001-07-24 Concat, Ltd. Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury
US20050112066A1 (en) 2003-11-26 2005-05-26 Concat Lp, A California Limited Partnership Complexes of cyclic polyaza chelators with cations of alkaline earth metals for enhanced biological activity
WO2012027727A2 (en) * 2010-08-26 2012-03-01 Kunyuan Cui Lipomacrocycles and uses thereof
WO2013060793A1 (en) 2011-10-25 2013-05-02 Technische Universität München Bifunctional ligands for radiometals
US10960088B2 (en) * 2013-09-12 2021-03-30 The Research Foundation For The State University Of New York Macrocycles, cobalt and iron complexes of same, and methods of making and using same
CN104119402B (zh) 2014-08-01 2016-08-24 南京大学 具有单分子磁行为和荧光精细结构的有机膦酸镝配合物
EP3624859A4 (en) * 2017-05-19 2021-03-03 The Research Foundation for The State University of New York Compounds for use as iron(iii) mri contrast agents
AU2019381793B2 (en) * 2018-11-16 2025-02-27 The Research Foundation For The State University Of New York Compounds for use as iron (III) MRI contrast agents containing anionic pendents and ancillary groups

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