|
US3907821A
(en)
|
1974-11-20 |
1975-09-23 |
Upjohn Co |
2-{8 3-{8 1-(DIMETHYLAMINO)CYCLOPROPYL{8 -4H-1,2,4-triazol-4-yl{8 {0 benzophenone
|
|
US4577020A
(en)
|
1983-01-25 |
1986-03-18 |
The Upjohn Company |
Aminoalkyl and aminoalkenyl triazoles as anti-psychotic agents
|
|
IL84093A
(en)
|
1986-10-09 |
1992-09-06 |
Ciba Geigy Ag |
Aralkyl-4h-1,2,4-triazole derivatives,their preparation and pharmaceutical compositions containing them
|
|
GB0101447D0
(en)
*
|
2001-01-19 |
2001-03-07 |
Univ Edinburgh |
Regulation of glucocorticoid concentration
|
|
GB0107383D0
(en)
*
|
2001-03-23 |
2001-05-16 |
Univ Edinburgh |
Lipid profile modulation
|
|
AUPR878201A0
(en)
|
2001-11-09 |
2001-12-06 |
Fujisawa Pharmaceutical Co., Ltd. |
New compounds
|
|
AU2002361861A1
(en)
|
2001-12-21 |
2003-07-30 |
Rhode Island Hospital |
SELECTIVE 11Beta-HSD INHIBITORS AND METHODS FOR USE THEREOF
|
|
AU2003207717B9
(en)
|
2002-02-01 |
2009-05-07 |
Merck & Co., Inc. |
11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
|
|
AR040241A1
(es)
|
2002-06-10 |
2005-03-23 |
Merck & Co Inc |
Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia
|
|
AR040847A1
(es)
|
2002-08-09 |
2005-04-20 |
Astrazeneca Ab |
1,2,4-oxadiazoles como moduladores de receptores de glutamato metabotropicos, para el tratamiento de desordenes neurologicos y psiquiatricos
|
|
JO2397B1
(en)
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
|
WO2004089367A1
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Pharmaceutical use of substituted 1,2,4-triazoles
|
|
JP2006522747A
(ja)
|
2003-04-11 |
2006-10-05 |
ノボ ノルディスク アクティーゼルスカブ |
縮合1,2,4−トリアゾールの薬学的使用
|
|
ATE482747T1
(de)
|
2003-04-11 |
2010-10-15 |
High Point Pharmaceuticals Llc |
Neue amide derivate und deren pharmazeutische verwendungen
|
|
US20060094699A1
(en)
*
|
2003-04-11 |
2006-05-04 |
Kampen Gita Camilla T |
Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist to minimize the side effects associated with glucocorticoid receptor agonist therapy
|
|
WO2004106294A2
(en)
|
2003-05-29 |
2004-12-09 |
Merck & Co., Inc. |
Triazole derivatives as inhibitors of 11-beta hydroxysteroid dehydrogenase-1
|
|
EP1680114A4
(en)
|
2003-10-28 |
2008-09-24 |
Amgen Inc |
TRIAZOL COMPOUNDS AND RELEVANT PROCEDURES
|
|
JP2005170939A
(ja)
|
2003-11-20 |
2005-06-30 |
Takeda Chem Ind Ltd |
糖尿病の予防・治療剤
|
|
BRPI0417687A
(pt)
|
2003-12-19 |
2007-04-03 |
Pfizer |
derivados de benzenossulfonilamino-piridin-2-ila e compostos relacionados como inibidores de 11-beta-hidroxiesteróide desidrogenase tipo 1 (11-beta-hsd-1) para o tratamento de diabetes e obesidade
|
|
BRPI0417947A
(pt)
|
2003-12-22 |
2007-04-17 |
Lilly Co Eli |
composto, composição farmacêutica, fabricação de um medicamento para o uso no tratamento e/ou prevenção de um metabólico distúrbio, e, formulação farmacêutica
|
|
CA2560314A1
(en)
|
2004-03-29 |
2005-10-20 |
Merck & Co., Inc. |
Diaryltriazoles as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
|
US7880001B2
(en)
*
|
2004-04-29 |
2011-02-01 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
|
US8415354B2
(en)
*
|
2004-04-29 |
2013-04-09 |
Abbott Laboratories |
Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
|
|
RU2383536C2
(ru)
|
2004-08-04 |
2010-03-10 |
Тайсо Фармасьютикал Ко., Лтд. |
Производное триазола
|
|
JP4882748B2
(ja)
|
2004-09-16 |
2012-02-22 |
アステラス製薬株式会社 |
トリアゾール誘導体またはその塩
|
|
US20090093463A1
(en)
|
2004-11-02 |
2009-04-09 |
Agouron Pharmaceuticals Inc. |
Novel compounds of substituted and unsubtituted adamantyl amides
|
|
WO2006068199A1
(ja)
|
2004-12-22 |
2006-06-29 |
Mochida Pharmaceutical Co., Ltd. |
代謝的に安定な3-オキシ-1,2,4-トリアゾール誘導体
|
|
WO2006080533A1
(ja)
|
2005-01-31 |
2006-08-03 |
Mochida Pharmaceutical Co., Ltd. |
3-アミノ-1,2,4-トリアゾール誘導体
|
|
WO2006134481A1
(en)
|
2005-06-16 |
2006-12-21 |
Pfizer Inc. |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type 1
|
|
CN101198605A
(zh)
|
2005-06-16 |
2008-06-11 |
辉瑞大药厂 |
N-(吡啶-2-基)-磺酰胺衍生物
|
|
EA200702498A1
(ru)
|
2005-06-16 |
2008-06-30 |
Пфайзер Инк. |
N-(пиридин-2-ил)сульфонамидные производные
|
|
WO2007007688A1
(ja)
|
2005-07-08 |
2007-01-18 |
Mochida Pharmaceutical Co., Ltd. |
3,5-ジアミノ-1,2,4-トリアゾール誘導体
|
|
CA2620179C
(en)
|
2005-08-16 |
2013-10-29 |
Icagen, Inc. |
Inhibitors of voltage-gated sodium channels
|
|
AR058807A1
(es)
|
2005-09-29 |
2008-02-27 |
Astrazeneca Ab |
5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5
|
|
ZA200807451B
(en)
|
2006-03-16 |
2010-01-27 |
Astellas Pharma Inc |
A triazole derivative or salt thereof
|
|
US20070224298A1
(en)
|
2006-03-23 |
2007-09-27 |
Talbott Shawn M |
Inhibiting 11(beta)-hsd1 with citrus flavonoids
|
|
US7435833B2
(en)
|
2006-04-07 |
2008-10-14 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
|
CN102076671B
(zh)
|
2008-07-03 |
2013-05-15 |
安斯泰来制药有限公司 |
三唑衍生物或其盐
|
|
EP2243494A1
(en)
*
|
2009-04-22 |
2010-10-27 |
OntoChem GmbH |
Pharmaceutical composition, comprising a steroid-dehydrogenase-reductase inhibitor, and a mineralocorticoid receptor antagonist.
|
|
WO2011068927A2
(en)
*
|
2009-12-04 |
2011-06-09 |
Abbott Laboratories |
11-β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11B-HSD1) INHIBITORS AND USES THEREOF
|
|
GB201003734D0
(en)
|
2010-03-05 |
2010-04-21 |
Univ Strathclyde |
Delayed prolonged drug delivery
|
|
UA112418C2
(uk)
|
2010-09-07 |
2016-09-12 |
Астеллас Фарма Інк. |
Терапевтичний болезаспокійливий засіб
|
|
BR112014018717A8
(pt)
*
|
2012-03-13 |
2017-07-11 |
Abbvie Inc |
Método para selecionar ou identificar um sujeito para terapia de antagonista de v1b
|
|
EP3166610B1
(en)
*
|
2014-07-09 |
2022-11-02 |
Eip Pharma, LLC |
Methods for treating neurologic disorders
|
|
US10894054B2
(en)
|
2015-04-07 |
2021-01-19 |
Intercept Pharmaceuticals, Inc. |
FXR agonist compositions for combination therapy
|
|
US10648506B2
(en)
|
2016-07-07 |
2020-05-12 |
Raul Mendoza |
Walking rig creeper interface
|
|
WO2018117063A1
(ja)
|
2016-12-20 |
2018-06-28 |
アステラス製薬株式会社 |
焦燥性興奮治療剤
|
|
CN113329754A
(zh)
|
2018-11-20 |
2021-08-31 |
麻雀制药股份有限公司 |
用于施用皮质类固醇的方法
|
|
EP3821892A1
(en)
|
2019-11-12 |
2021-05-19 |
University of Leeds |
(s)-2-(1-(5-(cyclohexylcarbamoyl)-6-(propylthio)pyridin-2-yl)piperidin-3-yl) acetic acid for use in treating wounds
|
|
EP3878446A1
(en)
|
2020-03-09 |
2021-09-15 |
Universite De Geneve |
Hsd11b1 inhibitors for use in immunotherapy and uses thereof
|
|
WO2023225507A1
(en)
|
2022-05-16 |
2023-11-23 |
Sparrow Pharmaceuticals, Inc. |
Methods and compositions for treating glucocorticoid excess
|
|
AU2023273030A1
(en)
|
2022-05-16 |
2024-11-07 |
Sparrow Pharmaceuticals, Inc. |
Methods and compositions for treating glucocorticoid excess
|