IL319327A - Methods of administering corticosteroids - Google Patents
Methods of administering corticosteroidsInfo
- Publication number
- IL319327A IL319327A IL319327A IL31932725A IL319327A IL 319327 A IL319327 A IL 319327A IL 319327 A IL319327 A IL 319327A IL 31932725 A IL31932725 A IL 31932725A IL 319327 A IL319327 A IL 319327A
- Authority
- IL
- Israel
- Prior art keywords
- urinary
- dose
- hsd
- inhibitor
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862769932P | 2018-11-20 | 2018-11-20 | |
| PCT/US2019/046449 WO2020106337A1 (en) | 2018-11-20 | 2019-08-14 | Methods for administering corticosteroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL319327A true IL319327A (en) | 2025-05-01 |
Family
ID=70774135
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL319327A IL319327A (en) | 2018-11-20 | 2019-08-14 | Methods of administering corticosteroids |
| IL283069A IL283069B2 (en) | 2018-11-20 | 2019-08-14 | Methods of administering corticosteroids |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL283069A IL283069B2 (en) | 2018-11-20 | 2019-08-14 | Methods of administering corticosteroids |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12220412B2 (enExample) |
| EP (1) | EP3883578A4 (enExample) |
| JP (2) | JP7472122B2 (enExample) |
| CN (1) | CN113329754A (enExample) |
| AU (2) | AU2019384074B2 (enExample) |
| BR (1) | BR112021009653A2 (enExample) |
| CA (1) | CA3120339A1 (enExample) |
| IL (2) | IL319327A (enExample) |
| MX (2) | MX2021005801A (enExample) |
| WO (1) | WO2020106337A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022076398A1 (en) * | 2020-10-07 | 2022-04-14 | Surface Ophthalmics, Inc. | Pharmaceutical kits and their use for treating dry eye disease |
| MX2021005801A (es) | 2018-11-20 | 2021-08-05 | Sparrow Pharmaceuticals Inc | Metodos para administrar corticosteroides. |
| MX2021007709A (es) | 2018-12-27 | 2021-12-15 | Surface Ophthalmics Inc | Composiciones farmacéuticas oftálmicas y procedimientos para el tratamiento de las enfermedades de la superficie ocular. |
| BR112021015481A2 (pt) * | 2019-02-08 | 2021-12-07 | Sanofi Sa | Otimização biotecnológica de micro-organismos para a 1,2-desidrogenação de esteroides |
| CN117979951A (zh) | 2021-05-10 | 2024-05-03 | 瑟菲斯眼科股份有限公司 | 一种用于缓解眼部疼痛的硫酸软骨素的用途 |
| US12440510B2 (en) | 2021-05-10 | 2025-10-14 | Surface Ophthalmics, Inc. | Use of chondroitin sulfate for relieving ocular pain |
| WO2023225507A1 (en) * | 2022-05-16 | 2023-11-23 | Sparrow Pharmaceuticals, Inc. | Methods and compositions for treating glucocorticoid excess |
| IL316907A (en) | 2022-05-16 | 2025-01-01 | Sparrow Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR TREATING GLUCOCORTICOD EXCESS |
| WO2025072521A1 (en) * | 2023-09-27 | 2025-04-03 | Sparrow Pharmaceuticals, Inc. | Methods and compositions for treating glucocorticoid-mediated diseases |
| GB202408335D0 (en) | 2024-06-11 | 2024-07-24 | Astrazeneca Ab | Therapies for wound treatment |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907821A (en) | 1974-11-20 | 1975-09-23 | Upjohn Co | 2-{8 3-{8 1-(DIMETHYLAMINO)CYCLOPROPYL{8 -4H-1,2,4-triazol-4-yl{8 {0 benzophenone |
| US4577020A (en) | 1983-01-25 | 1986-03-18 | The Upjohn Company | Aminoalkyl and aminoalkenyl triazoles as anti-psychotic agents |
| IL84093A (en) | 1986-10-09 | 1992-09-06 | Ciba Geigy Ag | Aralkyl-4h-1,2,4-triazole derivatives,their preparation and pharmaceutical compositions containing them |
| GB0101447D0 (en) * | 2001-01-19 | 2001-03-07 | Univ Edinburgh | Regulation of glucocorticoid concentration |
| GB0107383D0 (en) * | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
| AUPR878201A0 (en) | 2001-11-09 | 2001-12-06 | Fujisawa Pharmaceutical Co., Ltd. | New compounds |
| WO2003059267A2 (en) | 2001-12-21 | 2003-07-24 | Rhode Island Hospital | SELECTIVE 11β-HSD INHIBITORS AND METHODS FOR USE THEREOF |
| WO2003065983A2 (en) | 2002-02-01 | 2003-08-14 | Merck & Co., Inc. | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia |
| AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
| RU2352568C9 (ru) | 2002-08-09 | 2009-06-27 | Астразенека Аб | [1,2,4]оксадиазолы (варианты), способ их получения, фармацевтическая композиция и способ ингибирования активации метаботропных глютаматных рецепторов-5 |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| DE602004027171D1 (de) | 2003-04-11 | 2010-06-24 | High Point Pharmaceuticals Llc | Verbindungen mit Aktivität an der 11Beta-Hydroxasteroiddehydrogenase |
| WO2004089367A1 (en) | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | Pharmaceutical use of substituted 1,2,4-triazoles |
| WO2004089380A2 (en) | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | Pharmaceutical use of fused 1,2,4-triazoles |
| US20060094699A1 (en) * | 2003-04-11 | 2006-05-04 | Kampen Gita Camilla T | Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist to minimize the side effects associated with glucocorticoid receptor agonist therapy |
| JP4499106B2 (ja) | 2003-05-29 | 2010-07-07 | メルク・シャープ・エンド・ドーム・コーポレイション | 11−ベータ−水酸化ステロイド脱水素酵素−1の阻害剤としてのトリアゾール誘導体 |
| EP1680114A4 (en) | 2003-10-28 | 2008-09-24 | Amgen Inc | TRIAZOL COMPOUNDS AND RELEVANT PROCEDURES |
| JP2005170939A (ja) | 2003-11-20 | 2005-06-30 | Takeda Chem Ind Ltd | 糖尿病の予防・治療剤 |
| JP2007514731A (ja) | 2003-12-19 | 2007-06-07 | ファイザー インコーポレイテッド | 糖尿病及び肥満症の治療のための11−ベータ−ヒドロキシステロイドデヒドロゲナーゼ1型(11−β−hsd−1)の阻害剤としてのベンゼンスルホニルアミノ−ピリジン−2−イル誘導体及び関連化合物 |
| US7507832B2 (en) | 2003-12-22 | 2009-03-24 | Eli Lilly And Company | Triazole PPAR modulators |
| JP2007530690A (ja) | 2004-03-29 | 2007-11-01 | メルク エンド カムパニー インコーポレーテッド | 11−β−ヒドロキシステロイドデヒドロゲナーゼ−1の阻害剤としてのジアリールトリアゾール |
| US8415354B2 (en) * | 2004-04-29 | 2013-04-09 | Abbott Laboratories | Methods of use of inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme |
| US7880001B2 (en) * | 2004-04-29 | 2011-02-01 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme |
| WO2006013948A1 (ja) | 2004-08-04 | 2006-02-09 | Taisho Pharmaceutical Co., Ltd. | トリアゾール誘導体 |
| EP1790641A4 (en) | 2004-09-16 | 2009-08-26 | Astellas Pharma Inc | DERIVATIVE OF TRIAZOLE OR SALT OF SAID DERIVATIVE |
| EP1812407A2 (en) | 2004-11-02 | 2007-08-01 | Pfizer, Inc. | Novel compounds of substituted and unsubstituted adamantyl amides |
| WO2006068199A1 (ja) | 2004-12-22 | 2006-06-29 | Mochida Pharmaceutical Co., Ltd. | 代謝的に安定な3-オキシ-1,2,4-トリアゾール誘導体 |
| WO2006080533A1 (ja) | 2005-01-31 | 2006-08-03 | Mochida Pharmaceutical Co., Ltd. | 3-アミノ-1,2,4-トリアゾール誘導体 |
| WO2006134481A1 (en) | 2005-06-16 | 2006-12-21 | Pfizer Inc. | Inhibitors of 11-beta hydroxysteroid dehydrogenase type 1 |
| DE602006010546D1 (de) | 2005-06-16 | 2009-12-31 | Pfizer | N-(pyridin-2-yl)sulfonamidderivate |
| CN101198605A (zh) | 2005-06-16 | 2008-06-11 | 辉瑞大药厂 | N-(吡啶-2-基)-磺酰胺衍生物 |
| JPWO2007007688A1 (ja) | 2005-07-08 | 2009-01-29 | 持田製薬株式会社 | 3,5−ジアミノ−1,2,4−トリアゾール誘導体 |
| EP1922068A4 (en) | 2005-08-16 | 2010-08-11 | Icagen Inc | INHIBITORS OF VOLTAGE-CONTROLLED SODIUM CHANNELS |
| AR058807A1 (es) | 2005-09-29 | 2008-02-27 | Astrazeneca Ab | 5-(fenilisoxazoletoxi)-triazol-3-il piridinas sustituidas, para el tratamiento de trastornos mediados por el receptor mglur5 |
| US20090082367A1 (en) | 2006-03-16 | 2009-03-26 | Astellas Pharma Inc. | Triazole derivative or a salt thereof |
| US20070224298A1 (en) | 2006-03-23 | 2007-09-27 | Talbott Shawn M | Inhibiting 11(beta)-hsd1 with citrus flavonoids |
| US7435833B2 (en) | 2006-04-07 | 2008-10-14 | Abbott Laboratories | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme |
| SMT201700154T1 (it) | 2008-07-03 | 2017-05-08 | Astellas Pharma Inc | Derivato di triazolo o suo sale |
| EP2243494A1 (en) * | 2009-04-22 | 2010-10-27 | OntoChem GmbH | Pharmaceutical composition, comprising a steroid-dehydrogenase-reductase inhibitor, and a mineralocorticoid receptor antagonist. |
| WO2011068927A2 (en) | 2009-12-04 | 2011-06-09 | Abbott Laboratories | 11-β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11B-HSD1) INHIBITORS AND USES THEREOF |
| GB201003734D0 (en) * | 2010-03-05 | 2010-04-21 | Univ Strathclyde | Delayed prolonged drug delivery |
| UA112418C2 (uk) * | 2010-09-07 | 2016-09-12 | Астеллас Фарма Інк. | Терапевтичний болезаспокійливий засіб |
| WO2013135769A1 (en) * | 2012-03-13 | 2013-09-19 | Abbvie Inc. | Method for selecting or identifying a subject for v1b antagonist therapy |
| CN106659723A (zh) * | 2014-07-09 | 2017-05-10 | 爱普制药有限责任公司 | 用于治疗神经病症的方法 |
| MA41083A1 (fr) | 2015-04-07 | 2018-05-31 | Intercept Pharmaceuticals Inc | Compositions pharmaceutiques pour thérapie combinée |
| US10648506B2 (en) | 2016-07-07 | 2020-05-12 | Raul Mendoza | Walking rig creeper interface |
| WO2018117063A1 (ja) | 2016-12-20 | 2018-06-28 | アステラス製薬株式会社 | 焦燥性興奮治療剤 |
| MX2021005801A (es) | 2018-11-20 | 2021-08-05 | Sparrow Pharmaceuticals Inc | Metodos para administrar corticosteroides. |
| EP3821892A1 (en) | 2019-11-12 | 2021-05-19 | University of Leeds | (s)-2-(1-(5-(cyclohexylcarbamoyl)-6-(propylthio)pyridin-2-yl)piperidin-3-yl) acetic acid for use in treating wounds |
| EP3878446A1 (en) | 2020-03-09 | 2021-09-15 | Universite De Geneve | Hsd11b1 inhibitors for use in immunotherapy and uses thereof |
| WO2023225507A1 (en) | 2022-05-16 | 2023-11-23 | Sparrow Pharmaceuticals, Inc. | Methods and compositions for treating glucocorticoid excess |
| IL316907A (en) | 2022-05-16 | 2025-01-01 | Sparrow Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR TREATING GLUCOCORTICOD EXCESS |
-
2019
- 2019-08-14 MX MX2021005801A patent/MX2021005801A/es unknown
- 2019-08-14 WO PCT/US2019/046449 patent/WO2020106337A1/en not_active Ceased
- 2019-08-14 CA CA3120339A patent/CA3120339A1/en active Pending
- 2019-08-14 US US17/289,516 patent/US12220412B2/en active Active
- 2019-08-14 IL IL319327A patent/IL319327A/en unknown
- 2019-08-14 BR BR112021009653-1A patent/BR112021009653A2/pt unknown
- 2019-08-14 IL IL283069A patent/IL283069B2/en unknown
- 2019-08-14 AU AU2019384074A patent/AU2019384074B2/en active Active
- 2019-08-14 JP JP2021525303A patent/JP7472122B2/ja active Active
- 2019-08-14 EP EP19886299.7A patent/EP3883578A4/en active Pending
- 2019-08-14 CN CN201980076112.6A patent/CN113329754A/zh active Pending
-
2021
- 2021-05-17 MX MX2025002836A patent/MX2025002836A/es unknown
-
2024
- 2024-04-10 JP JP2024063590A patent/JP2024098991A/ja active Pending
- 2024-12-13 US US18/980,242 patent/US20250205227A1/en active Pending
-
2025
- 2025-04-30 AU AU2025203033A patent/AU2025203033A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3883578A4 (en) | 2022-07-27 |
| MX2021005801A (es) | 2021-08-05 |
| JP2024098991A (ja) | 2024-07-24 |
| US20210393622A1 (en) | 2021-12-23 |
| CN113329754A (zh) | 2021-08-31 |
| CA3120339A1 (en) | 2020-05-28 |
| WO2020106337A1 (en) | 2020-05-28 |
| EP3883578A1 (en) | 2021-09-29 |
| JP2022507103A (ja) | 2022-01-18 |
| IL283069A (en) | 2021-06-30 |
| US20250205227A1 (en) | 2025-06-26 |
| US12220412B2 (en) | 2025-02-11 |
| MX2025002836A (es) | 2025-04-02 |
| JP7472122B2 (ja) | 2024-04-22 |
| AU2019384074B2 (en) | 2025-04-10 |
| AU2025203033A1 (en) | 2025-05-22 |
| AU2019384074A1 (en) | 2021-06-03 |
| BR112021009653A2 (pt) | 2021-08-17 |
| IL283069B1 (en) | 2025-05-01 |
| IL283069B2 (en) | 2025-09-01 |
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