JP2022502378A5 - - Google Patents
Info
- Publication number
- JP2022502378A5 JP2022502378A5 JP2021516619A JP2021516619A JP2022502378A5 JP 2022502378 A5 JP2022502378 A5 JP 2022502378A5 JP 2021516619 A JP2021516619 A JP 2021516619A JP 2021516619 A JP2021516619 A JP 2021516619A JP 2022502378 A5 JP2022502378 A5 JP 2022502378A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- composition
- composition according
- combination
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736246P | 2018-09-25 | 2018-09-25 | |
| US62/736,246 | 2018-09-25 | ||
| PCT/US2019/052410 WO2020068657A1 (en) | 2018-09-25 | 2019-09-23 | 2'-halogenated-4'-thio-2'-deoxy-5-azacytidine analogs and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022502378A JP2022502378A (ja) | 2022-01-11 |
| JP2022502378A5 true JP2022502378A5 (https=) | 2022-09-08 |
| JP7520822B2 JP7520822B2 (ja) | 2024-07-23 |
Family
ID=68136598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021516619A Active JP7520822B2 (ja) | 2018-09-25 | 2019-09-23 | ２’－ハロゲン化－４’－チオ－２’－デオキシ－５－アザシチジンアナログおよびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20220033387A1 (https=) |
| EP (1) | EP3856754A1 (https=) |
| JP (1) | JP7520822B2 (https=) |
| CN (1) | CN112888698A (https=) |
| AU (1) | AU2019349424B2 (https=) |
| CA (1) | CA3110224A1 (https=) |
| WO (1) | WO2020068657A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3856754A1 (en) * | 2018-09-25 | 2021-08-04 | The United States of America, as represented by the Secretary, Department of Health and Human Services | 2'-halogenated-4'-thio-2'-deoxy-5-azacytidine analogs and use thereof |
| EP4138843A4 (en) * | 2020-04-23 | 2024-07-10 | Southern Research Institute | COMPOSITION FOR THE TREATMENT OF BLOOD CANCER USING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE AND USES THEREOF |
| CN114644668B (zh) * | 2020-12-18 | 2026-04-14 | 鲁南制药集团股份有限公司 | 一种合成地西他滨的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| CA1256638A (en) | 1984-07-06 | 1989-06-27 | Motoaki Tanaka | Polymer and its production |
| JP2551756B2 (ja) | 1985-05-07 | 1996-11-06 | 武田薬品工業株式会社 | ポリオキシカルボン酸エステルおよびその製造法 |
| WO1997038001A1 (en) * | 1996-04-09 | 1997-10-16 | Yamasa Corporation | 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL)CYTOSINES |
| EP2336140B1 (en) * | 2004-10-25 | 2016-01-27 | Dekk-Tec, Inc. | Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents |
| US20060128654A1 (en) | 2004-12-10 | 2006-06-15 | Chunlin Tang | Pharmaceutical formulation of cytidine analogs and derivatives |
| US7700567B2 (en) * | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
| RU2559364C2 (ru) | 2009-12-18 | 2015-08-10 | Либрамедисина, Инк. | СПОСОБ ПОЛУЧЕНИЯ ЗАМЕЩЕННЫХ 1-О-АЦИЛ-2-ДЕЗОКСИ-2-ФТОР-4-ТИО-β-D-АРАБИНОФУРАНОЗ |
| SG10201603288XA (en) | 2012-03-28 | 2016-05-30 | Fujifilm Corp | Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine |
| KR20170001722A (ko) | 2012-08-13 | 2017-01-04 | 후지필름 가부시키가이샤 | 1-(2-데옥시-2-플루오로-4-티오-β-D-아라비노푸라노실)시토신의 합성 중간체, 티오뉴클레오시드의 합성 중간체, 및 그들의 제조법 |
| CN103626765B (zh) * | 2012-08-27 | 2016-08-10 | 广东东阳光药业有限公司 | 取代的氮杂吲哚化合物及其盐、组合物和用途 |
| EP3109245B1 (en) | 2014-02-18 | 2018-01-03 | FUJIFILM Corporation | Method for producting thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate |
| JP6450356B2 (ja) | 2016-02-29 | 2019-01-09 | 富士フイルム株式会社 | 液状医薬製剤 |
| EP3746452B1 (en) | 2018-02-01 | 2023-09-13 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Stereoselective synthesis and process for the manufacturing of 2'-deoxynucleosides |
| EP3856754A1 (en) * | 2018-09-25 | 2021-08-04 | The United States of America, as represented by the Secretary, Department of Health and Human Services | 2'-halogenated-4'-thio-2'-deoxy-5-azacytidine analogs and use thereof |
-
2019
- 2019-09-23 EP EP19782886.6A patent/EP3856754A1/en not_active Withdrawn
- 2019-09-23 WO PCT/US2019/052410 patent/WO2020068657A1/en not_active Ceased
- 2019-09-23 AU AU2019349424A patent/AU2019349424B2/en not_active Ceased
- 2019-09-23 CA CA3110224A patent/CA3110224A1/en active Pending
- 2019-09-23 JP JP2021516619A patent/JP7520822B2/ja active Active
- 2019-09-23 US US17/278,625 patent/US20220033387A1/en not_active Abandoned
- 2019-09-23 CN CN201980062607.3A patent/CN112888698A/zh active Pending
-
2021
- 2021-06-09 US US17/343,350 patent/US11254662B2/en not_active Expired - Fee Related
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