JP2022501065A5 - - Google Patents

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Publication number
JP2022501065A5
JP2022501065A5 JP2021539334A JP2021539334A JP2022501065A5 JP 2022501065 A5 JP2022501065 A5 JP 2022501065A5 JP 2021539334 A JP2021539334 A JP 2021539334A JP 2021539334 A JP2021539334 A JP 2021539334A JP 2022501065 A5 JP2022501065 A5 JP 2022501065A5
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JP
Japan
Prior art keywords
seq
antibody
antigen
binding fragment
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021539334A
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English (en)
Japanese (ja)
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JP2022501065A (ja
JP7654548B2 (ja
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Priority claimed from PCT/US2019/050110 external-priority patent/WO2020060781A1/en
Publication of JP2022501065A publication Critical patent/JP2022501065A/ja
Publication of JP2022501065A5 publication Critical patent/JP2022501065A5/ja
Priority to JP2024127876A priority Critical patent/JP2024156878A/ja
Application granted granted Critical
Publication of JP7654548B2 publication Critical patent/JP7654548B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021539334A 2018-09-17 2019-09-06 抗klrg1抗体 Active JP7654548B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024127876A JP2024156878A (ja) 2018-09-17 2024-08-02 抗klrg1抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862732329P 2018-09-17 2018-09-17
US62/732,329 2018-09-17
PCT/US2019/050110 WO2020060781A1 (en) 2018-09-17 2019-09-06 Anti-klrg1 antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024127876A Division JP2024156878A (ja) 2018-09-17 2024-08-02 抗klrg1抗体

Publications (3)

Publication Number Publication Date
JP2022501065A JP2022501065A (ja) 2022-01-06
JP2022501065A5 true JP2022501065A5 (enExample) 2022-09-14
JP7654548B2 JP7654548B2 (ja) 2025-04-01

Family

ID=69887899

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021539334A Active JP7654548B2 (ja) 2018-09-17 2019-09-06 抗klrg1抗体
JP2024127876A Pending JP2024156878A (ja) 2018-09-17 2024-08-02 抗klrg1抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024127876A Pending JP2024156878A (ja) 2018-09-17 2024-08-02 抗klrg1抗体

Country Status (13)

Country Link
US (1) US12365735B2 (enExample)
EP (1) EP3852779A4 (enExample)
JP (2) JP7654548B2 (enExample)
KR (1) KR102934267B1 (enExample)
CN (2) CN112752580B (enExample)
AU (1) AU2019344524A1 (enExample)
BR (1) BR112021004553A2 (enExample)
CA (1) CA3113069A1 (enExample)
EA (1) EA202190647A1 (enExample)
IL (2) IL281594B2 (enExample)
MX (2) MX2021003119A (enExample)
SG (1) SG11202102114UA (enExample)
WO (1) WO2020060781A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021004553A2 (pt) 2018-09-17 2021-06-08 Abcuro, Inc. anticorpos anti-klrg1
WO2022056289A1 (en) * 2020-09-11 2022-03-17 National Jewish Health Methods and compositions for treating respiratory diseases or conditions related to innate lymphoid cells
WO2022204529A1 (en) 2021-03-26 2022-09-29 Abcuro, Inc. Anti-klrg1 antibodies
CA3212311A1 (en) * 2021-03-26 2022-09-29 Abcuro, Inc. Anti-klrg1 antibodies
WO2024072872A2 (en) * 2022-09-27 2024-04-04 The Brigham And Women's Hospital, Inc. Klrg1 signalling therapy for infectious disease

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
GB9809951D0 (en) 1998-05-08 1998-07-08 Univ Cambridge Tech Binding molecules
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
TWI380996B (zh) 2004-09-17 2013-01-01 Hoffmann La Roche 抗ox40l抗體
WO2006047350A2 (en) 2004-10-21 2006-05-04 Xencor, Inc. IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION
AU2005335714B2 (en) 2004-11-10 2012-07-26 Macrogenics, Inc. Engineering Fc antibody regions to confer effector function
AU2005304624B2 (en) 2004-11-12 2010-10-07 Xencor, Inc. Fc variants with altered binding to FcRn
EP1858925A2 (en) 2005-01-12 2007-11-28 Xencor, Inc. Antibodies and fc fusion proteins with altered immunogenicity
KR101523391B1 (ko) 2006-12-27 2015-05-27 에모리 유니버시티 감염 및 종양 치료를 위한 조성물 및 방법
KR20160070165A (ko) 2008-02-08 2016-06-17 메디뮨 엘엘씨 Fc 리간드 친화성이 감소된 항-IFNAR1 항체
WO2011016238A1 (en) 2009-08-06 2011-02-10 Immunas Pharma, Inc. Antibodies that specifically bind to a beta oligomers and use thereof
US10053513B2 (en) 2009-11-30 2018-08-21 Janssen Biotech, Inc. Antibody Fc mutants with ablated effector functions
SG188285A1 (en) * 2010-09-02 2013-04-30 Vaccinex Inc Anti-cxcl13 antibodies and methods of using the same
ES2692268T5 (en) 2011-03-29 2025-02-26 Roche Glycart Ag Antibody fc variants
JP6152090B2 (ja) 2011-04-21 2017-06-21 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド,ア ボディー コーポレイトTHE REGENTS OF THE UNIVERSITY OF COLORADO,a body corporate 視神経脊髄炎を処置するための組成物および方法
DK3424953T3 (en) 2011-06-06 2020-11-02 Novo Nordisk As Terapeutiske antistoffer
JPWO2012176765A1 (ja) 2011-06-24 2015-02-23 株式会社ペルセウスプロテオミクス 抗ヒトp−カドへリン(cdh3)遺伝子組み換え抗体
WO2014177459A2 (en) 2013-04-29 2014-11-06 F. Hoffmann-La Roche Ag Fc-receptor binding modified asymmetric antibodies and methods of use
JP2017518958A (ja) 2014-03-19 2017-07-13 マッカイ メディカル ファウンデイション ザ プレスビテリアン チャーチ イン タイワン マッカイ メモリアル ホスピタルMackay Medical Foundation The Presbyterian Church In Taiwan Mackay Memorial Hospital 免疫原性グリコペプチドに対する抗体、それを含む組成物、及びそれらの使用
WO2016009487A1 (ja) 2014-07-14 2016-01-21 三菱電機株式会社 空気調和装置
HUE068868T2 (hu) 2015-07-30 2025-02-28 Macrogenics Inc PD-1-hez kötõdõ molekulák és alkalmazásukra szolgáló eljárások
WO2017053469A2 (en) 2015-09-21 2017-03-30 Aptevo Research And Development Llc Cd3 binding polypeptides
AU2016334623A1 (en) 2015-10-07 2018-02-15 F. Hoffmann-La Roche Ag Bispecific antibodies with tetravalency for a costimulatory TNF receptor
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
WO2017152102A2 (en) 2016-03-04 2017-09-08 Alector Llc Anti-trem1 antibodies and methods of use thereof
JP2019518791A (ja) 2016-06-03 2019-07-04 ザ・ブリガム・アンド・ウィメンズ・ホスピタルThe Brigham and Women’s Hospital Klrg1シグナリングセラピー
AU2017326003A1 (en) 2016-09-16 2019-04-11 Children's Medical Center Corporation KLRG1 depletion therapy
US20190336615A1 (en) 2017-01-27 2019-11-07 Silverback Therapeutics, Inc. Tumor targeting conjugates and methods of use thereof
CA3059938A1 (en) 2017-04-14 2018-10-18 Kodiak Sciences Inc. Complement factor d antagonist antibodies and conjugates thereof
CN111093702A (zh) 2017-06-22 2020-05-01 财团法人生物技术开发中心 靶细胞依赖性T细胞的接合和活化型不对称异二聚Fc-ScFv融合抗体形式用于癌症治疗
WO2019169229A1 (en) 2018-03-01 2019-09-06 Nextcure, Inc. Klrg1 binding compositions and methods of use thereof
BR112021004553A2 (pt) 2018-09-17 2021-06-08 Abcuro, Inc. anticorpos anti-klrg1
AU2020272939A1 (en) 2019-04-09 2021-11-11 Abcuro, Inc. Killer cell lectin-like receptor subfamily G member 1 (KLRG1) depleting antibodies
CA3212311A1 (en) 2021-03-26 2022-09-29 Abcuro, Inc. Anti-klrg1 antibodies

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