JP2022501024A5 - - Google Patents

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Publication number
JP2022501024A5
JP2022501024A5 JP2021514998A JP2021514998A JP2022501024A5 JP 2022501024 A5 JP2022501024 A5 JP 2022501024A5 JP 2021514998 A JP2021514998 A JP 2021514998A JP 2021514998 A JP2021514998 A JP 2021514998A JP 2022501024 A5 JP2022501024 A5 JP 2022501024A5
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wing segment
modified oligonucleotide
nucleosides
segment
compound
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JP2021514998A
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Japanese (ja)
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JP7110485B2 (ja
JP2022501024A (ja
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Priority claimed from PCT/US2019/051743 external-priority patent/WO2020061200A1/en
Publication of JP2022501024A publication Critical patent/JP2022501024A/ja
Publication of JP2022501024A5 publication Critical patent/JP2022501024A5/ja
Priority to JP2022115413A priority Critical patent/JP7422816B2/ja
Application granted granted Critical
Publication of JP7110485B2 publication Critical patent/JP7110485B2/ja
Priority to JP2024004430A priority patent/JP2024026778A/ja
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JP2021514998A 2018-09-19 2019-09-18 Ｐｎｐｌａ３発現のモジュレーター Active JP7110485B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022115413A JP7422816B2 (ja) 2018-09-19 2022-07-20 Ｐｎｐｌａ３発現のモジュレーター
JP2024004430A JP2024026778A (ja) 2018-09-19 2024-01-16 Ｐｎｐｌａ３発現のモジュレーター

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862733152P 2018-09-19 2018-09-19
US62/733,152 2018-09-19
PCT/US2019/051743 WO2020061200A1 (en) 2018-09-19 2019-09-18 Modulators of pnpla3 expression

Related Child Applications (1)

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JP2022115413A Division JP7422816B2 (ja) 2018-09-19 2022-07-20 Ｐｎｐｌａ３発現のモジュレーター

Publications (3)

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JP2022501024A JP2022501024A (ja) 2022-01-06
JP2022501024A5 true JP2022501024A5 (enExample) 2022-03-31
JP7110485B2 JP7110485B2 (ja) 2022-08-01

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JP2021514998A Active JP7110485B2 (ja) 2018-09-19 2019-09-18 Ｐｎｐｌａ３発現のモジュレーター
JP2022115413A Active JP7422816B2 (ja) 2018-09-19 2022-07-20 Ｐｎｐｌａ３発現のモジュレーター
JP2024004430A Pending JP2024026778A (ja) 2018-09-19 2024-01-16 Ｐｎｐｌａ３発現のモジュレーター

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JP2022115413A Active JP7422816B2 (ja) 2018-09-19 2022-07-20 Ｐｎｐｌａ３発現のモジュレーター
JP2024004430A Pending JP2024026778A (ja) 2018-09-19 2024-01-16 Ｐｎｐｌａ３発現のモジュレーター

Country Status (25)

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US (4) US10774333B2 (enExample)
EP (1) EP3853365A4 (enExample)
JP (3) JP7110485B2 (enExample)
KR (2) KR102796176B1 (enExample)
CN (2) CN118576613A (enExample)
AR (1) AR114738A1 (enExample)
AU (2) AU2019345031B2 (enExample)
BR (1) BR112021004859A2 (enExample)
CA (1) CA3112036A1 (enExample)
CL (1) CL2021000650A1 (enExample)
CO (1) CO2021004141A2 (enExample)
CR (2) CR20210180A (enExample)
DO (1) DOP2021000044A (enExample)
EA (1) EA202190708A1 (enExample)
EC (1) ECSP21026021A (enExample)
IL (2) IL281492B2 (enExample)
JO (1) JOP20210050B1 (enExample)
MX (3) MX2021003170A (enExample)
MY (1) MY205135A (enExample)
NI (1) NI202100018A (enExample)
PE (1) PE20211051A1 (enExample)
PH (1) PH12021550558A1 (enExample)
SG (1) SG11202102636UA (enExample)
TW (3) TWI869213B (enExample)
WO (1) WO2020061200A1 (enExample)

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CA3065523A1 (en) 2017-06-02 2018-12-06 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
US11603532B2 (en) 2017-06-02 2023-03-14 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
JP2021521140A (ja) 2018-04-12 2021-08-26 ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． オリゴヌクレオチド組成物及びその使用方法
CA3098624A1 (en) 2018-05-11 2019-11-14 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
TWI869213B (zh) * 2018-09-19 2025-01-01 美商Ionis製藥公司 Pnpla3表現之調節劑
US20230357768A1 (en) * 2020-09-17 2023-11-09 Astrazeneca Ab Pharmaceutical compositions comprising an antisense oligonucleotide for oral administration
KR20230171431A (ko) * 2021-04-14 2023-12-20 다이서나 파마수이티컬, 인크. Pnpla3 발현을 조절하기 위한 조성물 및 방법
TW202313974A (zh) 2021-06-08 2023-04-01 瑞典商阿斯特捷利康公司 用於治療肝病之組合療法
WO2023183801A2 (en) * 2022-03-23 2023-09-28 Amgen Inc. Rnai constructs for inhibiting pnpla3 expression and methods of use thereof
JP2025542119A (ja) * 2022-12-07 2025-12-25 シャンハイ アルゴ バイオファーマシューティカル カンパニー，リミテッド パタチン様ホスホリパーゼドメイン含有３（ｐｎｐｌａ３）の発現を阻害するための組成物及び方法
TW202539705A (zh) * 2024-04-03 2025-10-16 瑞典商阿斯特捷利康公司 Ｐｎｐｌａ３表現之抑制劑的劑量依賴性投予
WO2026108959A1 (zh) * 2024-11-22 2026-05-28 苏州瑞博生物技术股份有限公司 寡核苷酸、寡核苷酸缀合物及组合物和用途

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