JP2022191257A5 - - Google Patents

Download PDF

Info

Publication number
JP2022191257A5
JP2022191257A5 JP2022150366A JP2022150366A JP2022191257A5 JP 2022191257 A5 JP2022191257 A5 JP 2022191257A5 JP 2022150366 A JP2022150366 A JP 2022150366A JP 2022150366 A JP2022150366 A JP 2022150366A JP 2022191257 A5 JP2022191257 A5 JP 2022191257A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
therapeutically effective
effective amount
amount
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022150366A
Other languages
English (en)
Japanese (ja)
Other versions
JP7402945B2 (ja
JP2022191257A (ja
Filing date
Publication date
Priority claimed from JP2019543937A external-priority patent/JP7146782B2/ja
Application filed filed Critical
Publication of JP2022191257A publication Critical patent/JP2022191257A/ja
Publication of JP2022191257A5 publication Critical patent/JP2022191257A5/ja
Application granted granted Critical
Publication of JP7402945B2 publication Critical patent/JP7402945B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022150366A 2017-02-16 2022-09-21 統合失調症を処置する方法 Active JP7402945B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762459784P 2017-02-16 2017-02-16
US62/459,784 2017-02-16
JP2019543937A JP7146782B2 (ja) 2017-02-16 2018-02-16 統合失調症を処置する方法
PCT/US2018/000078 WO2018151861A1 (en) 2017-02-16 2018-02-16 Methods of treating schizophrenia

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019543937A Division JP7146782B2 (ja) 2017-02-16 2018-02-16 統合失調症を処置する方法

Publications (3)

Publication Number Publication Date
JP2022191257A JP2022191257A (ja) 2022-12-27
JP2022191257A5 true JP2022191257A5 (US20070167479A1-20070719-C00034.png) 2023-05-25
JP7402945B2 JP7402945B2 (ja) 2023-12-21

Family

ID=61692045

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019543937A Active JP7146782B2 (ja) 2017-02-16 2018-02-16 統合失調症を処置する方法
JP2022150366A Active JP7402945B2 (ja) 2017-02-16 2022-09-21 統合失調症を処置する方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019543937A Active JP7146782B2 (ja) 2017-02-16 2018-02-16 統合失調症を処置する方法

Country Status (10)

Country Link
US (2) US11129807B2 (US20070167479A1-20070719-C00034.png)
EP (1) EP3582815A1 (US20070167479A1-20070719-C00034.png)
JP (2) JP7146782B2 (US20070167479A1-20070719-C00034.png)
KR (1) KR102605854B1 (US20070167479A1-20070719-C00034.png)
CN (2) CN116808023A (US20070167479A1-20070719-C00034.png)
AU (2) AU2018220509B2 (US20070167479A1-20070719-C00034.png)
CA (1) CA3053903A1 (US20070167479A1-20070719-C00034.png)
IL (2) IL268694B2 (US20070167479A1-20070719-C00034.png)
MX (2) MX2019009763A (US20070167479A1-20070719-C00034.png)
WO (1) WO2018151861A1 (US20070167479A1-20070719-C00034.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2707067C2 (ru) 2009-12-04 2019-11-22 Суновион Фармасьютикалз, Инк. Полициклические соединения и способы их применения
EP3490607A4 (en) 2016-07-29 2020-04-08 Sunovion Pharmaceuticals Inc. COMPOUNDS AND COMPOSITIONS, AND USES THEREOF
CN116808023A (zh) 2017-02-16 2023-09-29 桑诺维恩药品公司 治疗精神分裂症的方法
JP7191085B2 (ja) 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク イソクロマン化合物およびその使用
MX2020008537A (es) 2018-02-16 2021-01-08 Sunovion Pharmaceuticals Inc Sales, formas cristalinas y metodos de produccion de las mismas.
WO2019161236A1 (en) * 2018-02-16 2019-08-22 Sunovion Pharmaceuticals Inc. Methods of treating social function disorders
US20200179336A1 (en) * 2018-12-06 2020-06-11 Sunovion Pharmaceuticals Inc. Methods of treating neurological and psychiatric disorders
IL297248A (en) 2020-04-14 2022-12-01 Sunovion Pharmaceuticals Inc (s)-(5,4-dihydro-7h-thiano[3,2-c]pyran-7-yl)-n-methylmethanamine for the treatment of neurological and psychiatric disorders
CN115677718A (zh) * 2021-07-30 2023-02-03 武汉思瓴生物科技有限公司 甲基甲胺类衍生物制剂、药物组合物及其应用
US20230241024A1 (en) 2021-09-23 2023-08-03 Sunovion Pharmaceuticals Inc. Methods of treating metabolic disorders
CN115677719A (zh) * 2022-10-27 2023-02-03 复旦大学 一种芳基并杂环化合物及其制备方法和用途

Family Cites Families (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4021451A (en) 1972-05-16 1977-05-03 American Home Products Corporation Process for preparing polycyclic heterocycles having a pyran ring
US4036842A (en) 1972-05-16 1977-07-19 American Home Products Corporation Process for preparing polycyclic heterocycles having a pyran ring
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4021452A (en) 1975-04-23 1977-05-03 American Cyanamid Company 2,5-Dihydro-2,5-dialkoxyfuran derivatives
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4127665A (en) 1978-01-18 1978-11-28 Pfizer Inc. Thienohydantoin derivatives
FR2459239A1 (fr) 1979-06-20 1981-01-09 Logeais Labor Jacques Nouveaux derives amines du benzothiazole, leur procede de preparation et leur application en therapeutique
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
PH30676A (en) 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
NZ228331A (en) 1988-03-16 1991-10-25 Zambeletti Spa L Amine- and amido-containing heterocyclic compounds and pharmaceutical compositions
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
DE3827727A1 (de) 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8824400D0 (en) 1988-10-18 1988-11-23 Glaxo Group Ltd Chemical compounds
EP0368175A1 (de) 1988-11-06 1990-05-16 Boehringer Ingelheim Kg 3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.
GB8827479D0 (en) 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
EP0416740A3 (en) 1989-08-08 1991-08-28 Beecham Group P.L.C. Novel compounds with renin-inhibiting activity
JPH0735373B2 (ja) 1989-08-11 1995-04-19 三共株式会社 カルボン酸アミド化合物
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
GB8926560D0 (en) 1989-11-24 1990-01-17 Zambeletti Spa L Pharmaceuticals
GB8927872D0 (en) 1989-12-08 1990-02-14 Beecham Group Plc Pharmaceuticals
US5032598A (en) 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
JPH03223277A (ja) 1989-12-29 1991-10-02 Yoshitomi Pharmaceut Ind Ltd ベンゾチオフェン誘導体
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
ZA912744B (en) 1990-03-23 1992-02-26 Zambeletti Spa L Pharmaceuticals
JPH049367A (ja) 1990-04-26 1992-01-14 Zeria Pharmaceut Co Ltd アリールアルカノイル誘導体,該化合物の製造中間体及びそれらを含有する医薬
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
GB9018139D0 (en) 1990-08-17 1990-10-03 Pfizer Ltd Therapeutic agents
NZ240155A (en) 1990-10-29 1992-10-28 Ishihara Sangyo Kaisha Heterocyclyl acyl and (hexahydro) indanyl acyl substituted hydrazine derivatives, preparation thereof and pesticidal compositions
DE4104257A1 (de) 1991-02-13 1992-08-20 Boehringer Ingelheim Kg Verwendung von anellierten tetrahydropyridinessigsaeurederivaten fuer die behandlung neurologischer erkrankungen
GB9104839D0 (en) 1991-03-07 1991-04-17 Zambeletti Spa L Novel compounds
NZ243065A (en) 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
PH31294A (en) 1992-02-13 1998-07-06 Thomae Gmbh Dr K Benzimidazolyl derivatives, pharmaceutical compositions containing these compounds and process for preparing them.
JP3223277B2 (ja) 1992-04-10 2001-10-29 カシオ計算機株式会社 楽音制御装置
FR2692264B1 (fr) 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
IT1255178B (it) 1992-06-26 1995-10-20 Pierrel Spa N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica
DE59308842D1 (de) 1992-12-02 1998-09-10 Ciba Geigy Ag Selektiv-herbizides Mittel
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
TW334423B (en) 1993-10-22 1998-06-21 Hoffmann La Roche Tricyclic 1-aminoethylpyrrole-derivatives
JP3163068B2 (ja) 1993-12-27 2001-05-08 日本建工株式会社 野縁取付け金具
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
FR2723091B1 (fr) 1994-07-29 1996-11-08 Esteve Labor Dr Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
FR2734819B1 (fr) 1995-05-31 1997-07-04 Adir Nouveaux composes de la piperazine, de la piperidine et de la 1,2,5,6-tetrahydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
WO1999046237A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases
ATE308546T1 (de) 1998-03-12 2005-11-15 Novo Nordisk As Modulatoren der protein tyrosin phosphatase (ptpases)
AU6325599A (en) 1998-10-21 2000-05-08 Dr. Reddy's Research Foundation New compounds, their preparation and use
JP3454427B2 (ja) 1998-12-14 2003-10-06 藤沢薬品工業株式会社 ピペラジン誘導体
AU776276B2 (en) 1999-01-19 2004-09-02 Neurosearch A/S Fused heterocyclic compounds and their use in the treatment of neurodegenerative diseases
US6313309B1 (en) 1999-04-05 2001-11-06 Ortho-Mcneil Pharmaceutical, Inc. 4-thionaphthyl—1H—imidazoles which are usefulα22-adrenoceptoR agonists/ antagonists
AU4589800A (en) 1999-05-05 2000-11-21 Darwin Discovery Limited 9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors
AU7476800A (en) 1999-09-10 2001-04-10 Novo Nordisk A/S Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48
ATE309250T1 (de) 1999-09-10 2005-11-15 Novo Nordisk As Modulatoren der protein tyrosin phosphatase (ptpases)
AU7961200A (en) 1999-10-29 2001-05-14 Kaken Pharmaceutical Co., Ltd. Urea derivative, process for producing the same, and medicine containing the urea derivative
AR030537A1 (es) 1999-11-05 2003-08-27 Abbott Lab Acidos quinolincarboxilicos y naftiridincarboxilico antibacterianos
US7112594B2 (en) 2000-08-09 2006-09-26 Mitsubishi Pharma Corporation Fused bicyclic amide compounds and medicinal use thereof
WO2002022614A1 (fr) 2000-09-12 2002-03-21 Sankyo Company,Limited Derives de quinolizine
WO2002102387A1 (en) 2001-06-18 2002-12-27 H. Lundbeck A/S Treatment of neuropathic pain
US20040180883A1 (en) 2001-07-11 2004-09-16 Jeremy Gilmore Pharmaceutical compounds with serotonin receptor activity
WO2003006455A1 (en) 2001-07-11 2003-01-23 Eli Lilly And Company Pharmaceutical compounds with serotonin receptor activity
MXPA04003954A (es) 2001-10-26 2004-11-29 Aventis Pharma Inc Bencimidazoles.
JP2003261566A (ja) 2002-03-11 2003-09-19 Sankyo Co Ltd キノリジンを含有する医薬
TW200930291A (en) 2002-04-29 2009-07-16 Bayer Cropscience Ag Pesticidal heterocycles
US7091232B2 (en) 2002-05-21 2006-08-15 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
US7358269B2 (en) 2002-05-21 2008-04-15 Allergan, Inc. 2-((2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)methyl)-3,4-dihydronapthalen-1(2H)-one
US7323485B2 (en) 2002-05-21 2008-01-29 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
US7276522B2 (en) 2002-05-21 2007-10-02 Allergan, Inc. 4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones, 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
SE0202134D0 (sv) 2002-07-08 2002-07-08 Astrazeneca Ab Therapeutic agents
EP2156830A1 (en) 2002-10-16 2010-02-24 Isis Innovation Limited Modulators of asparaginyl hydoxylase activity of FIH
EP1587482A4 (en) 2003-01-31 2010-08-25 Technion Res & Dev Foundation ANTI-INFLAMMATORY COMPOSITIONS AND USES THEREOF
TWI422583B (zh) 2003-03-07 2014-01-11 參天製藥股份有限公司 具有以4-吡啶烷硫基為取代基之新穎化合物
JP2004269449A (ja) 2003-03-11 2004-09-30 Ishihara Sangyo Kaisha Ltd ベンズアミド誘導体、それらの製造方法及びそれらを含有する有害生物防除剤
US20070154534A1 (en) * 2003-03-12 2007-07-05 Sheitman Brian B Use of secretin in the treatment of schizophrenia
US7205318B2 (en) 2003-03-18 2007-04-17 Bristol-Myers Squibb Company Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors
US20070010671A1 (en) 2003-03-31 2007-01-11 Yoshinori Sekiguchi Novel quinazoline derivatives and methods of treatment related to the use thereof
JP2005145859A (ja) 2003-11-13 2005-06-09 Nippon Steel Chem Co Ltd 脱水素化方法及び芳香族複素環化合物の製造方法
DE10360793A1 (de) 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
WO2005072412A2 (en) 2004-01-29 2005-08-11 Elixir Pharmaceuticals, Inc. Anti-viral therapeutics
DE102004004974A1 (de) 2004-01-31 2005-08-18 Aventis Pharma Deutschland Gmbh Thieno-Iminosäure-Derivate als Inhibitoren von Matrix-Metalloproteinasen
KR100553398B1 (ko) 2004-03-12 2006-02-16 한미약품 주식회사 티에노[3,2-c]피리딘 유도체의 제조 방법 및 이에사용되는 중간체
MX2007001129A (es) 2004-07-28 2007-04-19 Irm Llc Compuestos y composiciones como moduladores de receptores nucleares de hormonas esteroidales.
SE0401970D0 (sv) 2004-08-02 2004-08-02 Astrazeneca Ab Novel compounds
SE0401971D0 (sv) 2004-08-02 2004-08-02 Astrazeneca Ab Piperidne derivatives
EP1634873A1 (en) 2004-08-27 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
FR2875230A1 (fr) 2004-09-13 2006-03-17 Sanofi Aventis Sa Derives de pyrazole condense, leur preparation et leur application en therapeutique
JP2006117568A (ja) 2004-10-20 2006-05-11 Mitsubishi Pharma Corp チオフェン環を有する新規アミド誘導体及びその医薬としての用途
WO2006053274A2 (en) 2004-11-15 2006-05-18 Bristol-Myers Squibb Company 2-amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
GT200600078A (es) 2005-02-17 2007-04-12 Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquil condensados
DE602006015297D1 (de) 2005-04-22 2010-08-19 Daiichi Sankyo Co Ltd 3-azetidincarbonsäure-derivate zur verwendung als immunsuppressiva
WO2007001939A1 (en) 2005-06-27 2007-01-04 Janssen Pharmaceutica N.V. Tetrahydro-pyranopyrazole compounds displaying cannabinoid modulating activities
EP1896515A4 (en) 2005-06-27 2010-03-10 Du Pont ELECTRICALLY CONDUCTIVE POLYMER COMPOSITIONS
US20100168102A9 (en) 2005-07-11 2010-07-01 Devgen Nv Amide Derivatives as Kinase Inhibitors
US8846742B2 (en) 2006-02-14 2014-09-30 The Trustees Of Columbia University In The City Of New York Neuronal pain pathway modulators
EP1986638A2 (en) 2006-02-21 2008-11-05 Ampla Pharmaceuticals Inc. Cb1 antagonists and inverse agonists
EP1829869A1 (en) 2006-03-02 2007-09-05 Laboratorios Del Dr. Esteve, S.A. 4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands
WO2007126041A1 (ja) 2006-04-28 2007-11-08 Eisai R & D Management Co., Ltd. ベンゾイソオキサゾール化合物
US8153664B2 (en) 2006-10-04 2012-04-10 Schering Corporation Bicyclic and tricyclic derivatives as thrombin receptor antagonists
US7960569B2 (en) 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
AU2007321720A1 (en) 2006-11-15 2008-05-22 Genetic Technologies Limited Compounds, compositions and methods for controlling invertebrate pests
WO2009008906A2 (en) 2007-02-06 2009-01-15 The Trustees Of The University Of Pennsylvania Therapeutic compounds for blocking dna synthesis of pox viruses
US7598417B2 (en) 2007-04-12 2009-10-06 Allergan, Inc. Substituted fluoroethyl ureas as alpha 2 adrenergic agents
EP1982987A1 (en) 2007-04-16 2008-10-22 Laboratorios del Dr. Esteve S.A. Spiro-pyrano-pyrazole derivatives
EP1982714A1 (en) 2007-04-16 2008-10-22 Laboratorios del Dr. Esteve S.A. Pyrano-pyrazole-amines
EP2020414A1 (en) 2007-06-20 2009-02-04 Laboratorios del Dr. Esteve S.A. spiro[piperidine-4,4'-thieno[3,2-c]pyran] derivatives and related compounds as inhibitors of the sigma receptor for the treatment of psychosis
US8338623B2 (en) 2007-07-09 2012-12-25 Abbvie Inc. Compounds as cannabinoid receptor ligands
CA2706391A1 (en) 2007-11-21 2009-05-28 Janssen Pharmaceutica N.V. Spiropiperidines for use as tryptase inhibitors
US7973051B2 (en) 2007-11-30 2011-07-05 Hoffman-La Roche Inc. Aminothiazoles as FBPase inhibitors for diabetes
WO2009072621A1 (ja) 2007-12-07 2009-06-11 Nissan Chemical Industries, Ltd. 置換ジヒドロアゾール化合物及び有害生物防除剤
WO2009085256A1 (en) 2007-12-27 2009-07-09 Panacos Pharmaceuticals, Inc. Anti-hiv compounds
CN101759710B (zh) 2008-10-06 2011-10-05 山东轩竹医药科技有限公司 含有取代的氮杂环的头孢菌素衍生物
US9776963B2 (en) 2008-11-10 2017-10-03 The Trustees Of The University Of Pennsylvania Small molecule CD4 mimetics and uses thereof
AR075442A1 (es) 2009-02-16 2011-03-30 Abbott Gmbh & Co Kg Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
TW201038569A (en) 2009-02-16 2010-11-01 Abbott Gmbh & Co Kg Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
WO2011036889A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
SI2501704T1 (sl) 2009-11-16 2013-11-29 Eli Lilly Company Spojine spiropiperidina kot antagonisti oral-1 receptorja
UA107943C2 (en) 2009-11-16 2015-03-10 Lilly Co Eli Compounds of spiropiperidines as antagonists of the orl-1 receptors
RU2707067C2 (ru) 2009-12-04 2019-11-22 Суновион Фармасьютикалз, Инк. Полициклические соединения и способы их применения
KR101778320B1 (ko) 2009-12-28 2017-09-13 잇반샤단호우징 화루마바레프로제쿠토 시엥기코우 1,3,4-옥사디아졸-2-카르복사미드 화합물
EP2377850A1 (en) 2010-03-30 2011-10-19 Pharmeste S.r.l. TRPV1 vanilloid receptor antagonists with a bicyclic portion
EP2560636A4 (en) 2010-04-23 2013-11-27 Kineta Inc ANTIVIRAL COMPOUNDS
US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
US9051280B2 (en) 2010-08-13 2015-06-09 AbbVie Deutschland GmbH & Co. KG Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
EP2683710B1 (en) 2011-03-10 2017-07-19 Boehringer Ingelheim International GmbH Soluble guanylate cyclase activators
CN102731574B (zh) 2011-03-30 2016-03-02 中国人民解放军军事医学科学院毒物药物研究所 噻吩并吡啶类α-胺基苄基膦酸酯、其制备方法及用途
WO2013010453A1 (en) 2011-07-15 2013-01-24 Abbott Laboratories Chemoking receptor antagonists
KR101920169B1 (ko) 2014-07-23 2018-11-19 샤프 가부시키가이샤 표시 장치 및 그 구동 방법
CN116808023A (zh) 2017-02-16 2023-09-29 桑诺维恩药品公司 治疗精神分裂症的方法
MX2020008537A (es) 2018-02-16 2021-01-08 Sunovion Pharmaceuticals Inc Sales, formas cristalinas y metodos de produccion de las mismas.
WO2019161236A1 (en) 2018-02-16 2019-08-22 Sunovion Pharmaceuticals Inc. Methods of treating social function disorders
US20200179336A1 (en) 2018-12-06 2020-06-11 Sunovion Pharmaceuticals Inc. Methods of treating neurological and psychiatric disorders

Similar Documents

Publication Publication Date Title
JP2022191257A5 (US20070167479A1-20070719-C00034.png)
JP2023002662A5 (US20070167479A1-20070719-C00034.png)
JP2021098728A5 (US20070167479A1-20070719-C00034.png)
JP2019203003A (ja) 腸透過性亢進を治療するための組成物及び方法
JP2018518537A5 (US20070167479A1-20070719-C00034.png)
JPWO2021121367A5 (US20070167479A1-20070719-C00034.png)
JP2009514874A5 (US20070167479A1-20070719-C00034.png)
KR20100134032A (ko) 선별적 s1p₁ 수용체 작동약에 대한 투약 섭생
JP2020534270A5 (US20070167479A1-20070719-C00034.png)
JP2013509411A5 (US20070167479A1-20070719-C00034.png)
JP2017525713A5 (US20070167479A1-20070719-C00034.png)
JP2015528501A5 (US20070167479A1-20070719-C00034.png)
JP2019533660A5 (US20070167479A1-20070719-C00034.png)
JP2013536837A5 (US20070167479A1-20070719-C00034.png)
JP2022058873A5 (US20070167479A1-20070719-C00034.png)
JP2002544227A5 (US20070167479A1-20070719-C00034.png)
JPWO2019241442A5 (US20070167479A1-20070719-C00034.png)
JP2020500868A5 (US20070167479A1-20070719-C00034.png)
JP2021503448A5 (US20070167479A1-20070719-C00034.png)
JP2023011549A5 (US20070167479A1-20070719-C00034.png)
JPWO2021211489A5 (US20070167479A1-20070719-C00034.png)
JPWO2020163268A5 (US20070167479A1-20070719-C00034.png)
JPWO2020000092A5 (US20070167479A1-20070719-C00034.png)
JP6420923B1 (ja) 医薬
JPWO2020037152A5 (US20070167479A1-20070719-C00034.png)