JP2022166014A5 - - Google Patents
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- JP2022166014A5 JP2022166014A5 JP2022118437A JP2022118437A JP2022166014A5 JP 2022166014 A5 JP2022166014 A5 JP 2022166014A5 JP 2022118437 A JP2022118437 A JP 2022118437A JP 2022118437 A JP2022118437 A JP 2022118437A JP 2022166014 A5 JP2022166014 A5 JP 2022166014A5
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- biomarker
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- sample
- therapeutic compound
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662276700P | 2016-01-08 | 2016-01-08 | |
| US62/276,700 | 2016-01-08 | ||
| US201662404638P | 2016-10-05 | 2016-10-05 | |
| US62/404,638 | 2016-10-05 | ||
| JP2018535307A JP6880037B2 (ja) | 2016-01-08 | 2017-01-06 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
| JP2021077686A JP7113942B2 (ja) | 2016-01-08 | 2021-04-30 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021077686A Division JP7113942B2 (ja) | 2016-01-08 | 2021-04-30 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022166014A JP2022166014A (ja) | 2022-11-01 |
| JP2022166014A5 true JP2022166014A5 (https=) | 2023-02-02 |
Family
ID=59274055
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018535307A Active JP6880037B2 (ja) | 2016-01-08 | 2017-01-06 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
| JP2021077686A Active JP7113942B2 (ja) | 2016-01-08 | 2021-04-30 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
| JP2022118437A Pending JP2022166014A (ja) | 2016-01-08 | 2022-07-26 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018535307A Active JP6880037B2 (ja) | 2016-01-08 | 2017-01-06 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
| JP2021077686A Active JP7113942B2 (ja) | 2016-01-08 | 2021-04-30 | がんの治療方法と、治療法に対する臨床的感度の予測因子としてのバイオマーカーの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10648983B2 (https=) |
| EP (1) | EP3399980B1 (https=) |
| JP (3) | JP6880037B2 (https=) |
| KR (1) | KR20180095094A (https=) |
| AU (1) | AU2017205170B2 (https=) |
| CA (1) | CA3010801A1 (https=) |
| ES (1) | ES3042541T3 (https=) |
| IL (2) | IL296659A (https=) |
| MX (1) | MX390772B (https=) |
| WO (1) | WO2017120446A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL278381B2 (en) | 2013-12-06 | 2024-08-01 | Celgene Corp | Methods for determining the effectiveness of a drug for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancer |
| WO2016196580A1 (en) | 2015-06-02 | 2016-12-08 | Celgene Corporation | Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins |
| CA2999179A1 (en) | 2015-09-25 | 2017-03-30 | Celgene Corporation | Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs |
| CA3010801A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
| EP3728639B1 (en) | 2017-12-20 | 2023-05-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method of selection of an ire1-inhibitor therapy for patient suffering from cancer |
| EP3774815A1 (en) * | 2018-03-30 | 2021-02-17 | Biotheryx Inc. | Thienopyrimidinone compounds |
| BR112020023756A2 (pt) * | 2018-05-23 | 2021-02-09 | Celgene Corporation | tratamento de mieloma múltiplo e uso de biomarcadores para 4-(4-(4-(((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-4-il)oxi)metil)benzil)piperazin-1-il)-3-fluorobenzonitrila |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| WO2021047627A1 (zh) * | 2019-09-12 | 2021-03-18 | 南京明德新药研发有限公司 | 一种可降解蛋白的并环类化合物及其应用 |
| KR20220106976A (ko) * | 2019-10-28 | 2022-08-01 | 셀진 코포레이션 | 백혈병을 치료하는 방법, 및 요법에 대한 임상 민감도를 예측하기 위한 백혈병 줄기 세포 시그니처의 용도 |
| BR112022007996A2 (pt) * | 2019-10-28 | 2022-07-05 | Celgene Corp | Métodos para o tratamento e uso de biomarcadores para predizer a sensibilidade clínica à 2-(4-clorofenil)-n-((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-5-il)metil)-2,2-difluoroacetamida |
| US11031119B2 (en) * | 2019-11-13 | 2021-06-08 | Cube Click, Inc. | Dental images processed with deep learning for national security |
| AU2020396543A1 (en) * | 2019-12-06 | 2022-06-16 | Celgene Corporation | Processes for preparing 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide |
| KR102311390B1 (ko) * | 2020-03-03 | 2021-10-13 | 이화여자대학교 산학협력단 | 교모세포종 예후예측용 조성물 |
| EP4121051A4 (en) * | 2020-03-16 | 2024-04-17 | Celgene Corporation | COMBINATION THERAPY FOR ACUTE MYELOID LEUKEMIA |
| WO2021211742A1 (en) * | 2020-04-14 | 2021-10-21 | The General Hospital Corporation | Use of gcn2 inhibitors in treating mitochondrial myopathies and diseases associated with mitochondrial dysfunction |
| IL299344A (en) | 2020-06-25 | 2023-02-01 | Tolremo Therapeutics Ag | Combination of a cbp/p300 bromodomain inhibitor and a kras inhibitor for the treatment of cancer |
| WO2022066835A1 (en) | 2020-09-23 | 2022-03-31 | St. Jude Children's Research Hospital, Inc. | Substituted n-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)arylsulfonamide analogs as modulators of cereblon protein |
| EP4278014A1 (en) * | 2021-01-13 | 2023-11-22 | Monte Rosa Therapeutics, Inc. | Treatment of myc-driven cancers with gspt1 degraders |
| JP2024504932A (ja) | 2021-01-13 | 2024-02-02 | モンテ ローザ セラピューティクス， インコーポレイテッド | イソインドリノン化合物 |
| GB202104635D0 (en) * | 2021-03-31 | 2021-05-12 | Imperial College Innovations Ltd | Methods and compositions for identifying and treating GCN2-dependent cancers |
| BR112023020538A2 (pt) * | 2021-04-07 | 2024-01-23 | Tolremo Therapeutics Ag | Derivados heterocíclicos, composições farmacêuticas e seus usos no tratamento ou na melhoria de câncer |
| WO2022219412A1 (en) * | 2021-04-14 | 2022-10-20 | Monte Rosa Therapeutics Ag | Isoindolinone amide compounds useful to treat diseases associated with gspt1 |
| EP4431505A4 (en) | 2021-11-09 | 2025-09-24 | Korea Res Inst Chemical Tech | ISOINDOLINONE DERIVATIVE HAVING A GLUTARIMIDE MOTHER NUCLEUS AND ITS USE |
| KR102823538B1 (ko) | 2021-11-09 | 2025-06-23 | 한국화학연구원 | 글루타이미드 모핵을 갖는 이소인돌리논 유도체 및 이의 용도 |
| CN114660289A (zh) * | 2022-03-03 | 2022-06-24 | 中山大学附属第三医院 | 肝癌标志物及其应用 |
| WO2023201282A1 (en) * | 2022-04-14 | 2023-10-19 | Bristol-Myers Squibb Company | Novel gspt1 compounds and methods of use of the novel compounds |
| US20240115557A1 (en) * | 2022-07-29 | 2024-04-11 | The Brigham And Women's Hospital, Inc. | Inhibitors of rna-guided nucleases and uses thereof |
| CA3265653A1 (en) * | 2022-09-02 | 2024-03-07 | Deciphera Pharmaceuticals, Llc | ULK INHIBITORS AND THEIR METHODS OF USE |
| CN120322242A (zh) * | 2022-09-16 | 2025-07-15 | 联邦高等教育系统天普大学 | Bag3用于治疗心脏淀粉样变性的方法和用途 |
| KR20240066904A (ko) | 2022-11-08 | 2024-05-16 | 주식회사 온코드바이오 | 아릴시클로알킬아마이드 구조를 갖는 이소인돌리논 유도체 및 이의 용도 |
| KR20240066906A (ko) | 2022-11-08 | 2024-05-16 | 주식회사 온코드바이오 | 퀴놀린 아마이드 구조를 갖는 이소인돌리논 유도체 및 이의 용도 |
| KR102570883B1 (ko) * | 2023-04-13 | 2023-08-29 | (주) 사이러스테라퓨틱스 | 신규한 gspt1 분해제 및 이의 용도 |
| WO2025164957A1 (ko) * | 2024-01-31 | 2025-08-07 | 남부대학교산학협력단 | 인간화된 세레브론 넉인 마우스 모델 및 이를 이용한 다발성 골수종 항암화학요법의 효능 평가 방법 |
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| ES2872967T3 (es) | 2012-06-29 | 2021-11-03 | Celgene Corp | Métodos para determinar la eficacia de fármacos usando IKZF3 (AIOLOS) |
| TW201534305A (zh) | 2013-05-03 | 2015-09-16 | Celgene Corp | 使用組合療法治療癌症之方法 |
| IL278381B2 (en) | 2013-12-06 | 2024-08-01 | Celgene Corp | Methods for determining the effectiveness of a drug for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancer |
| KR20160090390A (ko) | 2013-12-06 | 2016-07-29 | 셀진 코포레이션 | 혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법 |
| US9499514B2 (en) | 2014-07-11 | 2016-11-22 | Celgene Corporation | Antiproliferative compounds and methods of use thereof |
| WO2016060702A1 (en) | 2014-10-13 | 2016-04-21 | Celgene Corporaton | Methods for treating solid tumors and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| WO2016196580A1 (en) | 2015-06-02 | 2016-12-08 | Celgene Corporation | Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins |
| WO2017024019A1 (en) | 2015-08-04 | 2017-02-09 | Celgene Corporation | Methods for treating chronic lymphocytic leukemia and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| WO2017027672A1 (en) | 2015-08-12 | 2017-02-16 | Celgene Corporation | Methods for treating solid tumors and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| CA2999179A1 (en) | 2015-09-25 | 2017-03-30 | Celgene Corporation | Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs |
| EP3399981B1 (en) * | 2016-01-08 | 2023-08-02 | Celgene Corporation | Solid forms of 2-(4-chlorophenyl)-n-((2-2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl) methyl)-2,2-difluoroacetamide, and their pharmaceutical compositions and uses |
| WO2017120437A1 (en) * | 2016-01-08 | 2017-07-13 | Celgene Corporation | Formulations of 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide |
| CA3010801A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
| BR112018075206A2 (pt) * | 2016-06-06 | 2019-03-19 | Celgene Corporation | tratamento de malignidade hematológica com 2-(4-clorofenil)-n-((2-(2,6-dioxopiperidin-3-il)-1-oxoisoindolin-5-il)metil)-2,2-difluoroacetamida |
-
2017
- 2017-01-06 CA CA3010801A patent/CA3010801A1/en active Pending
- 2017-01-06 ES ES17736415T patent/ES3042541T3/es active Active
- 2017-01-06 WO PCT/US2017/012496 patent/WO2017120446A1/en not_active Ceased
- 2017-01-06 MX MX2018008421A patent/MX390772B/es unknown
- 2017-01-06 US US15/400,766 patent/US10648983B2/en active Active
- 2017-01-06 JP JP2018535307A patent/JP6880037B2/ja active Active
- 2017-01-06 AU AU2017205170A patent/AU2017205170B2/en active Active
- 2017-01-06 KR KR1020187022882A patent/KR20180095094A/ko not_active Ceased
- 2017-01-06 IL IL296659A patent/IL296659A/en unknown
- 2017-01-06 EP EP17736415.5A patent/EP3399980B1/en active Active
-
2018
- 2018-07-03 IL IL260400A patent/IL260400B2/en unknown
-
2020
- 2020-04-03 US US16/840,299 patent/US11460471B2/en active Active
-
2021
- 2021-04-30 JP JP2021077686A patent/JP7113942B2/ja active Active
-
2022
- 2022-07-26 JP JP2022118437A patent/JP2022166014A/ja active Pending
- 2022-08-05 US US17/882,278 patent/US12474342B2/en active Active
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