JP2022111148A5 - - Google Patents
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- Publication number
- JP2022111148A5 JP2022111148A5 JP2022084854A JP2022084854A JP2022111148A5 JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5 JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5
- Authority
- JP
- Japan
- Prior art keywords
- icos
- bispecific antibody
- monomer
- antibody
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381239P | 2016-08-30 | 2016-08-30 | |
| US62/381,239 | 2016-08-30 | ||
| US201762456033P | 2017-02-07 | 2017-02-07 | |
| US62/456,033 | 2017-02-07 | ||
| US201762479723P | 2017-03-31 | 2017-03-31 | |
| US62/479,723 | 2017-03-31 | ||
| US15/623,314 | 2017-06-14 | ||
| US15/623,314 US10787518B2 (en) | 2016-06-14 | 2017-06-14 | Bispecific checkpoint inhibitor antibodies |
| JP2019511464A JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| PCT/US2017/049497 WO2018045110A1 (en) | 2016-08-30 | 2017-08-30 | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Division JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022111148A JP2022111148A (ja) | 2022-07-29 |
| JP2022111148A5 true JP2022111148A5 (enExample) | 2023-02-20 |
Family
ID=65632988
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| JP2022084854A Pending JP2022111148A (ja) | 2016-08-30 | 2022-05-24 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP3507306B1 (enExample) |
| JP (2) | JP7080219B2 (enExample) |
| KR (2) | KR102575681B1 (enExample) |
| CN (1) | CN110267990B (enExample) |
| AU (1) | AU2017321625A1 (enExample) |
| CA (1) | CA3035343A1 (enExample) |
| DK (1) | DK3507306T3 (enExample) |
| IL (1) | IL265046B2 (enExample) |
| MX (1) | MX2023006786A (enExample) |
| SG (1) | SG11201901712YA (enExample) |
| ZA (1) | ZA201901752B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112016004437A2 (pt) * | 2013-09-13 | 2017-10-17 | Genentech Inc | métodos de imunoteste e de seleção de linhagem de células, anticorpos e kit |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| AU2019371223B2 (en) * | 2018-10-31 | 2022-03-17 | Bioatla, Inc. | Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| CA3171597A1 (en) * | 2020-04-14 | 2021-10-21 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer |
| CN115698075A (zh) * | 2020-04-14 | 2023-02-03 | 葛兰素史密斯克莱知识产权发展有限公司 | 涉及抗icos和抗pd1抗体，任选地进一步涉及抗tim3抗体的癌症的组合治疗 |
| JP2023541853A (ja) * | 2020-09-08 | 2023-10-04 | ユーティレックス カンパニー リミテッド | Ｐｄ－１ポリペプチド変異体 |
| CN114195900B (zh) * | 2020-09-17 | 2024-02-23 | 普米斯生物技术(珠海)有限公司 | 一种抗4-1bb/pd-l1双特异性抗体及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8546543B2 (en) * | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| WO2010077634A1 (en) * | 2008-12-09 | 2010-07-08 | Genentech, Inc. | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| US8637024B2 (en) * | 2010-11-12 | 2014-01-28 | The Rockefeller University | Fusion antibodies for HIV therapy |
| AR091649A1 (es) * | 2012-07-02 | 2015-02-18 | Bristol Myers Squibb Co | Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos |
| HRP20191865T1 (hr) * | 2013-01-14 | 2020-01-10 | Xencor, Inc. | Novi heterodimerni proteini |
| CA3093606A1 (en) * | 2013-03-15 | 2014-09-18 | Xencor, Inc. | Heterodimeric proteins for induction of t cells |
| EP3587448B1 (en) * | 2013-03-15 | 2021-05-19 | Xencor, Inc. | Heterodimeric proteins |
| CA2918795A1 (en) * | 2013-07-25 | 2015-01-29 | Cytomx Therapeutics, Inc. | Multispecific antibodies, multispecific activatable antibodies and methods of using the same |
| ES2923641T3 (es) | 2013-12-30 | 2022-09-29 | Epimab Biotherapeutics Inc | Inmunoglobulina con Fabs en tándem y usos de la misma |
| MX389663B (es) * | 2014-10-14 | 2025-03-20 | Novartis Ag | Moleculas de anticuerpo que se unen a pd-l1 y usos de las mismas. |
| HRP20201756T8 (hr) * | 2014-11-21 | 2021-08-20 | Bristol-Myers Squibb Company | Antitijela koja sadrže modificirane regije teškog lanca |
| EP3223907A2 (en) * | 2014-11-26 | 2017-10-04 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and cd38 |
| HRP20191824T1 (hr) * | 2015-01-08 | 2020-01-24 | BioNTech SE | Agonistička sredstva za vezivanje tnf receptora |
| JP2018503399A (ja) * | 2015-01-14 | 2018-02-08 | コンパス セラピューティクス リミテッド ライアビリティ カンパニー | 多特異性免疫調節抗原結合構築物 |
| MA41414A (fr) * | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
-
2017
- 2017-08-30 JP JP2019511464A patent/JP7080219B2/ja active Active
- 2017-08-30 KR KR1020197009280A patent/KR102575681B1/ko active Active
- 2017-08-30 EP EP17765002.5A patent/EP3507306B1/en active Active
- 2017-08-30 KR KR1020237029969A patent/KR20230130174A/ko not_active Ceased
- 2017-08-30 AU AU2017321625A patent/AU2017321625A1/en not_active Abandoned
- 2017-08-30 CA CA3035343A patent/CA3035343A1/en active Pending
- 2017-08-30 CN CN201780060900.7A patent/CN110267990B/zh active Active
- 2017-08-30 IL IL265046A patent/IL265046B2/en unknown
- 2017-08-30 SG SG11201901712YA patent/SG11201901712YA/en unknown
- 2017-08-30 DK DK17765002.5T patent/DK3507306T3/da active
-
2019
- 2019-02-27 MX MX2023006786A patent/MX2023006786A/es unknown
- 2019-03-20 ZA ZA2019/01752A patent/ZA201901752B/en unknown
-
2022
- 2022-05-24 JP JP2022084854A patent/JP2022111148A/ja active Pending