JP2025118688A5 - - Google Patents

Info

Publication number
JP2025118688A5
JP2025118688A5 JP2025069830A JP2025069830A JP2025118688A5 JP 2025118688 A5 JP2025118688 A5 JP 2025118688A5 JP 2025069830 A JP2025069830 A JP 2025069830A JP 2025069830 A JP2025069830 A JP 2025069830A JP 2025118688 A5 JP2025118688 A5 JP 2025118688A5
Authority
JP
Japan
Prior art keywords
seq
antigen
humanized antibody
binding fragment
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025069830A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025118688A (ja
Filing date
Publication date
Priority claimed from JP2022518775A external-priority patent/JP7754506B2/ja
Application filed filed Critical
Publication of JP2025118688A publication Critical patent/JP2025118688A/ja
Publication of JP2025118688A5 publication Critical patent/JP2025118688A5/ja
Pending legal-status Critical Current

Links

JP2025069830A 2019-10-08 2025-04-21 ポリオウイルス受容体(pvr)に対する抗体およびその使用 Pending JP2025118688A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962912534P 2019-10-08 2019-10-08
US62/912,534 2019-10-08
JP2022518775A JP7754506B2 (ja) 2019-10-08 2020-10-07 ポリオウイルス受容体(pvr)に対する抗体およびその使用
PCT/IL2020/051082 WO2021070181A1 (en) 2019-10-08 2020-10-07 Antibodies against the poliovirus receptor (pvr) and uses thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022518775A Division JP7754506B2 (ja) 2019-10-08 2020-10-07 ポリオウイルス受容体(pvr)に対する抗体およびその使用

Publications (2)

Publication Number Publication Date
JP2025118688A JP2025118688A (ja) 2025-08-13
JP2025118688A5 true JP2025118688A5 (enExample) 2025-12-05

Family

ID=73038283

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022518775A Active JP7754506B2 (ja) 2019-10-08 2020-10-07 ポリオウイルス受容体(pvr)に対する抗体およびその使用
JP2025069830A Pending JP2025118688A (ja) 2019-10-08 2025-04-21 ポリオウイルス受容体(pvr)に対する抗体およびその使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022518775A Active JP7754506B2 (ja) 2019-10-08 2020-10-07 ポリオウイルス受容体(pvr)に対する抗体およびその使用

Country Status (11)

Country Link
US (1) US20220372161A1 (enExample)
EP (1) EP4041392A1 (enExample)
JP (2) JP7754506B2 (enExample)
KR (1) KR20220082007A (enExample)
CN (2) CN114502595B (enExample)
AU (1) AU2020363041B2 (enExample)
BR (1) BR112022006620A2 (enExample)
CA (1) CA3156983A1 (enExample)
IL (1) IL291540A (enExample)
MX (1) MX2022004194A (enExample)
WO (1) WO2021070181A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024011278A (es) 2022-03-15 2024-09-25 Compugen Ltd Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer.
KR102615797B1 (ko) * 2022-04-28 2023-12-19 가톨릭대학교 산학협력단 T 세포에 의한 교모세포종 치료 효과의 유효성 예측 방법
KR20250058747A (ko) 2022-09-04 2025-04-30 넥틴 테라퓨틱스 리미티드 인간화 항 pvr 항체의 약물 접합체
TW202515608A (zh) 2023-06-26 2025-04-16 以色列商坎布根有限公司 Il—18bp拮抗抗體及其於癌症治療之單一療法及組合療法的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
DE3883899T3 (de) 1987-03-18 1999-04-22 Sb2, Inc., Danville, Calif. Geänderte antikörper.
EP0940468A1 (en) 1991-06-14 1999-09-08 Genentech, Inc. Humanized antibody variable domain
WO1994029351A2 (en) 1993-06-16 1994-12-22 Celltech Limited Antibodies
KR101077001B1 (ko) 1999-01-15 2011-10-26 제넨테크, 인크. 효과기 기능이 변화된 폴리펩티드 변이체
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
EP1481993A1 (en) 2003-05-28 2004-12-01 Xerion Pharmaceuticals AG Modulation of the poliovirus receptor function
JP6296650B2 (ja) 2013-03-13 2018-03-20 国立大学法人 筑波大学 免疫疾患に対する医薬組成物
JP6180663B2 (ja) * 2014-12-23 2017-08-16 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Tigitに対する抗体
JP5995117B2 (ja) 2015-01-26 2016-09-21 国立大学法人 筑波大学 可溶型cd155タンパク質を用いた癌の検出方法
US20180251548A1 (en) 2015-09-14 2018-09-06 Compass Therapeutics Llc Compositions and methods for treating cancer via antagonism of the cd155/tigit pathway and tgf-beta
EP4043492A1 (en) * 2016-03-01 2022-08-17 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Antibodies specific to human poliovirus receptor (pvr)

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